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Research

  • Dr. Clauden Louis

    Dr. Clauden Louis

  • Dr. Bart Simon

    Dr. Bart Simon

  • Dr. Amber Melvin with Dr. Hicks

    Dr. Amber Melvin with Dr. Hicks

  • Dr. Bart Simon

    Dr. Bart Simon

  • Dr. Katherine Wood

    Dr. Katherine Wood

Resident Research

The divisions of Cardiac and Thoracic/Foregut Surgery offer a wide range of research projects for residents to choose from. Projects are available through the Cardiovascular Research Institute, our large animal research lab, the Thoracic Esophageal Motility Lab, or collaboration projects with medical device industry. We are very flexible and allow residents to pursue research in Cardiothoracic Surgery that will enhance their surgical training. Residents are encouraged to participate in research and publish with the faculty. For those interested in spending a dedicated year in academic pursuits, a full year in the lab is possible to enhance the trainee's academic growth.

Recent Resident Research Activities

Manuscripts

  • Centennial Meeting Boston MA May 1, 2017
    Modified Repair of Type I and II Truncus Arteriosus Limits Early Right Ventricular Outflow Tract Re-operation 
    Louis C, Swartz MF, Simon BV, Cholette JM, Atallah-Yunes N, Wang H, Gensini F, Alfieris GM. (Oral Presentation AATS, Manuscript Seminars in Thoracic and Cardiovascular Surgery)
  • Current Opinion in Cardiology January 2018
    Hereditary arrhythmias and cardiomyopathies: decision-making about genetic testing 
    Louis C., Calamaro E., Vinocur J. (Manuscript
  • NASS The 33rd Annual Meeting Los Angeles, CA, September 26-29, 2018
    CT imaging of the spine in pediatric trauma patients: Prevalence of fractures and mechanisms of injury 
    Baldwin A, Louis C, Moses JT, Mesfin A (Oral Presentation NASS)
  • American College of CHEST Physicians October 9, 2018
    Prognosis of patients implanted with left ventricle assist device (LVAD) due to acute cardiogenic shock 
    Louis C, Daimee, U., Gosev I., Prasad S., Kutyifa, V., Alexis, J. (Oral Presentation, First Place Award)
  • Pediatric Trauma Society (PTS) November 8-10, 2018
    Evaluation of CT imaging revealing axial fractures in the pediatric population following traumatic injury.
    Baldwin A, Louis C, Jefferson J, Mesfin A, Wakeman D (Oral Presentation PTS)
  • HeartMate 3 Pump Exchange via Sternal-Sparing Bilateral Mini-Thoracotomies
    Journal of Cardiac Surgery
    Louis C, Ayers B, Barrus B, Prasad S, Alexis J, Bernstein WK, Cheyne CA, Gosev I (Manuscript)
  • Development and Evolution of the Thoracic Surgery Residents Association
    Lou X, , Brescia A, Louis C, Han J, Blitzer D, Mehaffey JH
    (Annals of Thoracic Surgery Manuscript Accepted)

Poster Presentations

  • American Heart Association Resuscitation Science Symposium November 16-17, 2019
    Risk of Adverse Events with Left Ventricular Assist Device in Cardiogenic Shock Patients
    Louis C (Poster Presentation AHA)
  • ECTSS Opal Sands Clearwater Florida October 19, 2018
    Recapturing a Non-recapturable Transcatheter Aortic Valve Status-post Mal-deployment: A Case 
    Louis C, Allphin C, Bernstein W (Poster Presentation ECTSS)
  • ECTSS Opal Sands Clearwater Florida October 19, 2018
    Persistent Left SVC with Absent Right SVC in a Patient with a Secundum Atrial Septal Defect 
    Cifuentes R, Louis C, Cardarelli F (Poster Presentation ECTSS)
  • ECTSS Opal Sands Clearwater Florida October 19, 2018
    Percutaneous device closure of rare large pseudoaneurysm following in situ reconstruction of infected prosthetic aorta using cryopreserved cadaveric allograft 
    Robinson DA, Ling F, Louis C, Wood KL, Johnson Jr. CA and Knight PA (Poster Presentation ECTSS)
  • ISHLT Nice, France April 13, 2018
    Prognosis of patients implanted with left ventricle assist device (LVAD) due to acute cardiogenic shock
    Louis C, Daimee, U., Gosev I., Prasad S., Kutyifa, V., Alexis, J. (Poster Presentation ISHLT)
  • University of Rochester Medical Center Resident Research Fair April 5, 2018
    Prognosis of patients implanted with left ventricle assist device (LVAD) due to acute cardiogenic shock
    Louis C, Daimee, U., Gosev I., Prasad S., Kutyifa, V., Alexis, J. (Poster Presentation URMC)
  • ISMICS Italy Rome June 7-10, 2017
    Minimally Invasive Subaortic Membrane Resection of Atrial Myxoma with Patent Foramen Ovale with Embolic Phenomenon. 
    Louis C., Knight P (Poster ISMICS)
  • AATS Mitral Conclave New York, NY April 27, 2017
    Strenuous Exercise Activity Leading to Acute Mitral Valve Regurgitation 
    Siordia JA, Louis C, Knight P. (Poster Mitral Conclave)
  • AATS Mitral Conclave New York, NY April 27, 2017
    Successful Repeat Mitral Valve Replacement in the Setting of Concomitant Aortic and Tricuspid Valve Replacement and Repair: A Case Report.
    Louis C, Knight P (Poster Mitral Conclave)
  • HVS Monaco FR March 2-4, 2017
    A rare case of bioprosthetic mitral valve endocarditis due to C. parapsilopsis: A Case Report Literature Review
    Louis C, Siordia JA, Prasad SM (Poster Heart Valve Society)
  • HVS Monaco FR March 2-4, 2017
    Subaortic membrane with congenital absence of pericardium and persistent left superior vena cava corrected with mini-thoracotomy incision
    Siordia JA, Louis C, Knight P (Poster Heart Valve Society)

Book Chapters

  • Thoracoabdominal Aortic Aneurysm Repair: Current Discoveries and Operative Management (2016). 
    Horizons in World Cardiovascular Research. Volume 12. Hauppage, NY: NOVA Science Publishers
    Siordia J, Louis C.
  • TSRA Decision Algorithms in Cardiothoracic Surgery: STEMI (7/2019)
    Ragalie WS, Louis C, Banharash P
  • TSRA Decision Algorithms in Cardiothoracic Surgery: Cardiogenic Shock Post-STEMI (7/2019)
    Louis C, Luc JGY, Prasad S
  • TSRA Decision Algorithms in Cardiothoracic Surgery: Mitral Stenosis (7/2019)
    Louis C, Prasad S
  • TSRA Decision Algorithms in Cardiothoracic Surgery: Interstitial Lung Disease (7/2019)
    Louis C, Peyre C
  • TSRA Decision Algorithms in Cardiothoracic Surgery: Lung Volume Reduction Surgery (7/2019)
    Louis C, Peyre C
  • TSRA Clinical Scenarios Decision: Minimally Invasive Cardiac Surgery Pending Publication (8/2020)
    Louis C, Ziazedeh D, Knight P
  • TSRA Clinical Scenarios Decision: Mechanical Circulatory Support Pending Publication (8/2020)
    Ziazedeh D, Louis C, Prasad S
  • TSRA Clinical Scenarios Decision: Arrhythmia Surgery Publication (8/2020)
    Louis C, Ziazedeh D, Knight P
  • TSRA Clinical Scenarios Decision: Left Ventricular Assist Device Publication (8/2020)
    Louis C, Ziazedeh D, Gosev I

Textbook Editor

  • TSRA Decision Algorithms in Cardiothoracic Surgery: Publication 7/2019 (Best Seller)
    Louis C, Vardas P, Chen P, Dixon J, Amin P
  • TSRA Clinical Scenarios Decision: Publication 8/2020
    Watson J, Louis C, Brescia A, Bloom J, Coyan G

Cardiothoracic Surgery Residency Awards

 
  • 1/2020 - 2020 Thoracic Surgery Resident Association (TSRA)/ Society of Thoracic Surgeons (STS) Global Fellowship Award Recipient $5,000
  • 12/2019 - Cardiothoracic Ethics Forum Scholarship Recipient Society of Thoracic Surgeons (STS)/American Association Thoracic Surgery (AATS) $2,500
  • 11/2019 - Dartmouth National Implementation Science Program Scholar Recipient (NISP) in Cardiac Surgery
  • 7/2019 - Society of Thoracic Surgeons (STS): 2019 Advocacy Scholarship $500
  • 3/2019 - American College Surgeons (ACS): 2019 Leadership Advocacy Scholarship $500
  • 11/2018 - 2018 CHEST Society Alfred Soffer Research Award: First Place Oral Presentation $500

Publications

  • Bartholomew V. Simon MD, Gisela Beutner PhD, Michael F. Swartz PhD, George M. Alfieris MD, George A. Porter, Jr. MD, PhD
    Poor Myocardial Protection Decreases Electron Transport Chain Monomers and Tetramers: Early Results from an Ovine Model of Neonatal Cardiac Surgery
    University of Rochester Department of Surgery Research Symposium Poster  
  • Bartholomew V. Simon MD, Michael F. Swartz PhD, Nader Atallah-Yunes MD, Jill M. Cholette MD, George M. Alfieris MD
    Five-Year Outcomes after Regionalizing Pediatric Cardiac Surgery Centers
    University of Rochester Department of Surgery Research Symposium Poster  
  • Bartholomew V. Simon MD, Gisela Beutner PhD, Michael F. Swartz PhD, George M. Alfieris MD, George A. Porter Jr. MD, PhD
    Cardioplegia-Induced Myocyte Arrest Alters Electron Transport Chain Assembly During Neonatal Cardiac Surgery
    Eastern Society for Pediatric Research Annual Meeting. Philadelphia, PA. 
    Platform- Young Investigator Award Finalist  
  • Bartholomew V. Simon MD, Gisela Beutner PhD, Michael F. Swartz PhD, George M. Alfieris MD, George A. Porter Jr. MD, PhD
    Cardioplegia-Induced Myocyte Arrest Alters ATP Synthase Multimer Assembly During Neonatal Cardiac Surgery
    Pediatric Academic Societies Annual Meeting. Toronto, ON.
    Platform- Travel Award Winner  
  • Bartholomew V. Simon MD, Subhashini Subramanian MD, Michael F. Swartz PhD, Nader Atallah-Yunes MD, George M. Alfieris MD
    Thirty Year Serial Follow-up of Two Surgical Strategies for the Repair of Tetralogy of Fallot.
    American Association for Thoracic Surgery Annual Meeting. San Diego, CA.
    Congenital Moderated Poster Competition
  • Simon BV, Gu Y, Wyrobek JA, Narins CR, Prasad SM. Direct right ventricular Impella LD implantation enables postoperative ambulation and may avoid sternal re-entry. J Card Surg. 2020; 35(7): 1700-1702. PMID 32400015
  • Simon BV, Swartz MF, Orie JM, Adams HR, Seltzer LE, Angona RE, Atallah-Yunes NH, Alfieris GM. Neurodevelopmental Delay following the Neonatal Repair of Coarctation and Arch Obstruction. Ann Thorac Surg. 2019; 108(5): 1416-1422. PMID 31207245
  • Swartz MF, Makhija P, Rubenstein J, Henrichs KF, Simon BV, Wang H, Powers KS, Alfieris GM, Blumberg N, Cholette JM. Met-hemoglobin is a Biomarker for Poor Oxygen Delivery in Infants Following Surgical Palliation. World J Pediatr Congenit Heart Surg. 2019; 10(4): 485-491. PMID 31142197
  • Simon BV, Subramanian S, Swartz MF, Wang H, Atallah-Yunes N, Alfieris GM. Serial Follow-Up of Two Surgical Strategies for the Repair of Tetralogy of Fallot. Semin Thorac Cardiovasc Surg. 2019; 31(3): 515-523. PMID 30616004
  • Simon BV, Swartz MF, Alfieris GM. Damus-Kaye-Stansel procedure avoids coronary obstruction in complex D-transposition. J Card Surg. 2018; 33(11): 756-758. PMID 30360013
  • Swartz MF, Orie JM, Egan M, Atallah-Yunes NH, Cholette JM, Simon BV, Smith FC, Wang H, Lipshultz SE, Alfieris GM. Five-year outcomes after regionalizing pediatric cardiac surgery centers. Prog Pediatr Cardiol. 2018; 50: 4-11.
  • Louis C, Swartz MF, Simon BV, Cholette JM,  Atallah-Yunes N, Wang H, Gensini F, Alfieris GM. Modified Repair of Type I and II Truncus Arteriosus Limits Early Right Ventricular Outflow Tract Reoperation. Semin Thorac Cardiovasc Surg. 2018; 30(2): 199-204. PMID 29428623
  • Simon BV, Swartz MF, Egan M, Cholette JM, Gensini F, Alfieris GM. Use of a Dacron Annular Sparing Versus Limited Transannular Patch With Nominal Pulmonary Annular Expansion in Infants With Tetralogy of Fallot. Ann Thorac Surg. 2017; 103(1): 186-192. PMID 27476822
  • Swartz MF, Simon B, Atallah-Yunes N, Cholette JM, Orie J, Gensini F, Alfieris GM. Distal Transverse Arch to Left Carotid Artery Ratio Helps to Identify Infants With Aortic Arch Hypoplasia. Ann Thorac Surg. 2015; 100(3): 1004-11; discussion 1011-2. PMID 26212512

Platform Presentations

  • Simon BV, Swartz MF, Beutner G, Westcott R, Belmont K, Porter GA, Alfieris GM. Dysregulation of Mitochondrial ATP Synthase: A Possible Mechanism for Cardiac Dysfunction following Neonatal Myocyte Arrest. AATS Annual Meeting. Toronto, ON. 2019.
    Winner, Congenital Mini Oral Competition
  • Simon BV, Swartz MF, Orie JM, Adams HR, Seltzer LE, Angona RE, Atallah-Yunes NH, Alfieris GM. Neurodevelopmental Delay following the Neonatal Repair of Coarctation and Arch Obstruction. STS Annual Meeting. San Diego, CA. 2019.
  • Simon BV, Beutner G, Swartz MF, Alfieris GM, Porter GA. Cardioplegia-Induced Myocyte Arrest Alters ATP Synthase Assembly During Neonatal Cardiac Surgery. PAS Annual Meeting. Toronto, ON. 2018.
  • Simon BV, Beutner G, Swartz MF, Alfieris GM, Porter GA. Cardioplegia-Induced Myocyte Arrest Alters Electron Transport Chain Assembly During Neonatal Cardiac Surgery. ESPR Annual Meeting. Philadelphia, PA. 2018.
    Finalist Presentation, Young Investigator Award
  • Simon BV, Swartz MF, Egan M, Cholette JM, Gensini F, Alfieris GM. Use of a Dacron Annular Sparing Versus Limited Transannular Patch With Nominal Pulmonary Annular Expansion in Infants With Tetralogy of Fallot. STS 52nd Annual Meeting. Phoenix, AZ. 2016.
  • Simon BV, Roztocil E, Kumar NG, Caliste XA, Doyle AJ, Bandyopadhyay G, Miller-Graziano C, Gillespie DL, Cullen JP. Carotid Artery Atherosclerosis: Biomarkers of Plaque Instability. Vascular Research Initiatives Conference. Orlando, FL. 2013.

Poster Presentations

  • Simon BV, Swartz MF, Atallah-Yunes N, Cholette JM, Alfieris GM. Five Year Outcomes after Regionalizing Pediatric Cardiac Surgery Centers. University of Rochester Department of Surgery Research Symposium. Rochester, NY. 2018.
    Winner, Best Translational Poster
  • Simon BV, Beutner G, Swartz MF, Alfieris GM, Porter GA. Poor Myocardial Protection Decreases Electron Transport Chain Monomers and Tetramers: Early Results from an Ovine Model of Neonatal Cardiac Surgery. University of Rochester Department of Surgery Research Symposium. Rochester, NY. 2018.
  • Simon BV, Subramanian S, Swartz MF, Atallah-Yunes N, Alfieris GM. Serial Follow-Up of Two Surgical Strategies for the Repair of Tetralogy of Fallot. AATS Annual Meeting Congenital Moderated Poster Competition. San Diego, CA. 2018.
  • Simon BV, Swartz MF, Atallah-Yunes N, Alfieris GM. Long Term Follow-Up after Limited Ventriculotomy in the Repair of Tetralogy of Fallot. University of Rochester Department of Surgery Research Symposium. Rochester, NY. 2017.
  • Simon BV, Swartz MF, Egan M, Cholette JM, Gensini F, Alfieris GM. Use of a Dacron Annular Sparing Versus Limited Transannular Patch With Nominal Pulmonary Annular Expansion in Infants With Tetralogy of Fallot. STS 52nd Annual Meeting. Phoenix, AZ. 2016.
  • Simon BV, Roztocil E, Kumar NG, Caliste XA, Doyle AJ, Bandyopadhyay G, Miller-Graziano C, Gillespie DL, Cullen JP. Carotid Artery Atherosclerosis: Biomarkers of Plaque Instability. Atherosclerosis, Thrombosis, and Vascular Biology Meeting. Orlando, FL. 2013.
  • Simon BV, Czaplicki C, Hogan E. Resveratrol Enhances Neurite Outgrowth by Affecting Microtubule Distribution in Growth Cones. American Society for Cell Biology Meeting. Philadelphia, PA. 2010.

Book Chapters

  • Simon BV, Swartz MF, Alfieris GM (2019). Congential Pulmonary Vein Anomalies. In TSRA Decision Algorithms in Cardiothoracic Surgery. Chicago, IL: Thoracic Surgery Residents Association.
  • Simon BV, Swartz MF, Alfieris GM (2019). Functional Single Ventricle Palliation. In TSRA Decision Algorithms in Cardiothoracic Surgery. Chicago, IL: Thoracic Surgery Residents Association.

Peer Review Publications

  • Ziazadeh D, Matar R, Himelhoch B, Borgman A2 Parker JL, Willekes CL, Timek TA. “Single-dose del Nido Cardioplegia in Minimally Invasive Aortic Valve Surgery.” Semin Thorac Cardiovasc Surg. 2017; 2017 Nov 2; PMID: 29104016
  • Ziazadeh D, Kumar N, Prasad S, Barrus B, Gosev I. “Images in Cardiothoracic Surgery: Retained ECMO Wire in CentriMag Pump.” Annals of Thoracic Surgery. Submitted. 2018; 2018 May 23rd

Abstracts

  • Timek, T., Willekes, C.L., Beute, T.A., Ziazadeh, D.R., Matar, R.N., Parker, J.L., Goehler, M.R., Fanning, F.S., Boeve, T., Murphy, E.T., Heiser, J.C., “Del Nido Cardioplegia in Adult Coronary Artery Bypass Grafting Surgery.” STS 54th Annual Meeting, Fort Lauderdale, FL, January 27-31 2018.

Presentations

  • Timek, T., Willekes, C.L., Beute, T.A., Ziazadeh, D.R., Matar, R.N., Parker, J.L., Goehler, M.R., Fanning, F.S., Boeve, T., Murphy, E.T., Heiser, J.C., “Del Nido Cardioplegia in Adult Coronary Artery Bypass Grafting Surgery.” Abstract accepted for podium presentation. STS 54th Annual Meeting, Fort Lauderdale, FL, January 27-31 2018.
  • Case Presentation: Ziazadeh, D.R. Redo Paraesophageal Hernia Repair – An Interesting Case. Intern Teaching Rounds with Dr. David Linehan – Chair Department of Surgery – University of Rochester Medical Center. 2017 October 19th; Rochester, NY.
  • Lecture: Ziazadeh, D.R. Paraesophageal Hernia Repair. Thoracic Indications Conference – University of Rochester Medical Center. 2017 October 19th; Rochester, NY.
  • Lecture: Ziazadeh, D.R. Right VATS Upper Lobectomy. Thoracic Indications Conference – University of Rochester Medical Center. 2017 November 2nd; Rochester, NY.
  • Case Presentation: Ziazadeh, D.R. Two Cases of Rare Cardiac Tumors. Cardiology Cath/CT Surgery Case Conference – University of Rochester Medical Center. 2018 April 18th; Rochester, NY.
  • Invited Talk: Ziazadeh, D.R. Lines, Tubes, and Drains. MS4 Intern Boot Camp – University of Rochester Medical Center. 2018 May 3rd; Rochester, NY.
  • Visiting Professor Case Presentation: Ziazadeh, D.R. Double CoreValve - TAVR. Dr. William Baumgartner - Vincent L. Gott Professor of Cardiac Surgery; Vice Dean for Clinical Affairs; President, Clinical Practice Association; and Associate Director, Cardiac Surgery Research Lab at Johns Hopkins University School of Medicine – University of Rochester Medical Center. 2018 May 11th; Rochester, NY.
  • Visiting Professor Case Presentation: Ziazadeh, D.R. Aortic Insufficiency after TAVR. Dr. George Sarosi - Vice-Chairman for Education, and Surgery Residency Program Director; Robert H. Hux, MD Professor of Surgery; Medical Director, UF Health & Shands Center for Experiential Learning; Assistant Chief of the Surgical Service; Director of Surgical Quality at No. Florida/So. Georgia VAMC; University of Florida College of Medicine – University of Rochester Medical Center. 2018 May 24th; Rochester, NY.