URMC / Center for RNA Biology / Employment Opportunities
Employment Opportunities
Post-Doctoral Fellows
A postdoctoral position is available in the laboratory of Dmitri Ermolenko at the Department of Biochemistry and Biophysics & Center for RNA Biology, School of Medicine and Dentistry, University of Rochester.
We use single-molecule fluorescent microscopy and biochemical methods to study how structural dynamics of the ribosome and ribosomal ligands enable protein synthesis. In addition to studying ribosomal translation in bacteria and eukaryotes, we investigate the folding and dynamics of structured mRNA molecules, including mRNAs containing riboswitches or structural elements that induce programmed ribosome frameshifting. Applicants must have a recent Ph.D. and expertise in molecular biology/biophysics with publications in international peer-reviewed journals.
Applicants with experience in RNA biochemistry and/or single-molecule FRET are encouraged to apply. Please submit a statement of research interests and experience, and a current curriculum vitae to Dr. Dmitri Ermolenko.
Graduate Students
Our lab is currently recruiting graduate students. Motivated candidates who are interested in studying mechanisms of bacterial and eukaryotic translation using ensemble and single-molecule fluorescent methods are encouraged to email Dr. Dmitri Ermolenko.
Join the Fu Lab as a postdoc!
We are seeking a postdoctoral candidate with outstanding experience in bioinformatics and transcriptomics, especially ribosome profiling. Current projects are aimed at understanding the role of RNA modifications in human disorders using mammalian tissue culture and mouse models.
Successful candidates are expected to have:
- PhD in Molecular Biology, Computational Biology or related field.
- Expertise in RNA biochemistry coupled with deep sequencing approaches such as ribosome profiling, CLIP-seq etc.
- Strong background in transcriptomics, bioinformatics and programming
- Self-motivation and the ability to work independently as well as collaboratively
Candidates should provide the following:
- Cover letter with a short statement of research experience, interests and goals
- CV with a publication list and contact information for at least two professional references.
Please submit all application materials electronically to: dragonyfu@rochester.edu
The position is available immediately with a flexible start date.
Post-doctoral and Technical Associate Opportunities in the Kielkopf Lab at the University of Rochester: Structural Biology of Pre-mRNA Splicing in Human Disease
Positions for post-doctoral and technical associates to study the structural biology of pre-mRNA splicing in human disease are available at the University of Rochester. Projects seek to understand severe defects in pre-mRNA splicing that accompany most human hematologic malignancies and many metabolic disorders, as well as the dependence of HIV-1 and other complex retroviruses on RNA splicing for infectivity at the structural and molecular level. We use multi-pronged and innovative approaches, including X-ray crystallography, fluorescence, calorimetry, small-angle X-ray scattering, HIV-1 assays and human cell culture.
For more information on projects, please see the Kielkopf lab website or contact Dr. Kielkopf.
Interested individuals should send a C.V., including a description of past and on-going research, and the names and contact information of three references to Dr. Kielkopf.
Successful applicants should be well-equipped to contribute to a productive group of interactive lab members with diverse backgrounds and expertise.
We are always interested in hearing from highly motivated, enthusiastic individuals interested in joining our research team.
Current Graduate Students
The Lueck Lab is currently accepting rotation students. Students interested in setting up a rotation should contact Dr. Lueck with your CV and research interests.
Post-doctoral Fellows
Individuals with interest in our multidisciplinary research are encouraged to send a CV and cover letter.
Undergraduate Students
Students interested in RNA biology and their use as therapeutics and skeletal muscle ion channel biophysics should contact Dr. Lueck with your CV and future research interests. Students with backgrounds in the Biological Sciences, Biomedical Engineering or related fields are encouraged to apply.
Post-Doctoral Opportunity
A Post-Doctoral Position is open in the Maquat Lab at the University of Rochester Medical Center in Rochester, NY. Applicants should hold a PhD or MD/PhD degree(s) and have expertise in molecular, cellular, or structural biology to study one of a number of very exciting and ongoing projects, including but not limited to FMRP function in Fragile X Syndrome (FXS), newly defined effectors of nonsense-mediated mRNA decay, or the mechanistic coupling of transcription and RNA processing on chromatin and beyond. A background in neurobiology and/or stem-cell biology would facilitate the work on FXS (see, e.g., https://www.nature.com/articles/s41556-020-00618-1), and a background in computational biology would facilitate all projects, but neither is required.
Interested individuals should submit:
1) a complete curriculum vitae,
2) the names and email addresses of three references (applicants should state their relationship to each), and
3) a description of RNA research experience, including experimental approaches and technologies with which the applicant has experience.
The successful applicant will join a very productive, interactive lab and a lively, supportive RNA community that consists of 23 labs spanning the University of Rochester Medical Center and the adjacent adjacent School of Arts & Sciences and Hajim School of Engineering & Applied Sciences. The Maquat lab offers an outstanding research environment, excellent opportunities to collaborate with basic scientists and clinicians, and a strong record of training post-docs for academic positions.
Please submit applications to: Liz at elizabeth_leverenz@urmc.rochester.edu
Maquat Lab: https://www.urmc.rochester.edu/labs/Maquat-Lab/
Center for RNA Biology: http://www.urmc.rochester.edu/rna-biology/
The University of Rochester is committed to diversity and equality in education and employment. EOE Minorities/Females/Protected Veterans/Disabled.
The pay range of $55,341 - $69,000 represents the minimum and maximum compensation for this job. Individual annual salaries/hourly rates will be set within the job’s compensation range, and will be determined by considering factors including, but not limited to, market data, education, experience, qualifications, expertise of the individual, and internal equity considerations.
Lab Technician Opportunity
There is a full-time laboratory technician position available (start-time is flexible) in the Maquat and Pröschel Labs to assist in day-to-day operations. The Maquat and Pröschel Labs seek to define a novel therapeutic for fragile X syndrome, the most common single-gene cause of intellectual disability and autism spectrum disorder, by dampening the efficiency of nonsense-mediated mRNA decay. Approaches utilize mice and cultured cells, including organoids.
Responsibilities consist of mouse husbandry/analyses and standard molecular biology experiments to quantitate proteins and RNAs. Organizational skills are critical. Prior laboratory experience is optional. Associate's degree in appropriate discipline plus 2-3 years specialized experience in related field required. BA/BS in Biochemistry, Chemistry, Biology, Neuroscience, Biomedical Engineering or a related field preferred.
All staff positions are posted on University job website. All applicants must apply through the University job website.
Maquat Lab: https://www.urmc.rochester.edu/labs/maquat.aspx
Pröschel Lab: https://www.urmc.rochester.edu/labs/proschel.aspx
Center for RNA Biology: https://www.urmc.rochester.edu/rna-biology.aspx
The University of Rochester is committed to diversity and equality in education and employment. EOE Minorities/Females/Protected Veterans/Disabled.
We're looking for motivated trainees at all levels! We are also hiring a laboratory technician. If you are interested, please contact Stephano Mello.
Trainees will be exposed to a collaborative and interdisciplinary environment and will receive a broad training in cancer research, including genomics-based approaches to study cancer and the use of animal models. Trainees are expected to develop and execute an independent research plan that lead to peer-reviewed publication. We strive to create a diverse, collegial environment, while fostering collaboration and intellectual rigour.
tRNA biology in model eukaryotes
A postdoctoral position is available in the laboratory of Eric Phizicky, Dept. of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, to work in the area of tRNA biology. Research in the lab focuses on the biology of tRNA modifications and tRNA decay pathways in two model organisms: the budding yeast Saccharomyces cerevisiae and the distantly related fission yeast Schizosaccharomyces pombe. The research employs cutting edge techniques in molecular biology, genetics, genomics, and biochemistry to understand problems in tRNA biology, most recently revealing interactions between the biology of modifications and a major cellular stress response pathway. Candidates should have a Ph.D. degree, with a background in genetics, molecular biology, biochemistry, biology, chemistry, pharmacology, or microbiology. Experience with molecular biology, RNA detection/quantification, protein expression/detection, enzyme assays, statistics, or computational analysis would be an asset.
To apply, please send an email to Dr. Eric Phizicky with a curriculum vitae, names of three references, and a brief summary of previous research experience and research interests.
Postdoctoral Position
A full-time postdoctoral associate position is available in Dr. Peng Yao’s laboratory in Aab Cardiovascular Research Institute at the University of Rochester Medical Center. Research in the Yao laboratory focuses on the roles of RNA-binding proteins and noncoding RNAs in cardiovascular health and disease. We aim to understand how translational regulation of protein synthesis influence cardiac health and disease and provide new insights into discovery of novel therapeutic approaches to treat heart disease. This position represents an opportunity to join a top-rated biomedical research campus. We are looking for candidates with experiences or interest in following areas: cardiac biology, cardiovascular disease, biochemistry and molecular biology, RNA biology, bioinformatic data analysis, and genetic and disease animal models.
Full Post-Doc Position