Faculty

Signaling transduction mechanisms in the vascular system

Basal ganglia and degenerative diseases

Understanding the mechanisms by which the extracellular matrix protein, fibronectin, affects cell and tissue functions that are critical for wound repair. We study both the structural mechanisms and intracellular signaling events that mediate cell and tissue responses to matrix fibronectin. In turn, we are using this information to develop novel technologies for tissue engineering, and therapeutic approaches to promote tissue regeneration in chronic wounds.

Synaptic pharmaco-physiology of vestibular efferent-afferent interactions

Molecular mechanisms of Neurodegeneration

Cancer immunotherapy/Host immune response to influenza infection/ Inflammation biology of sepsis

Mechanotransduction of musculoskeletal cells and associated human disease; Physiology and pathophysiology of mechanosensitive ion channels

Mechanisms of neurotransmitter receptor function

Environmental lung diseases COPD and IPF pathogenesis and therapeutic targets: effects of lung cellular mitochondrial dysfunction, senescence, and molecular clock.

Thrombosis and platelet activation in vascular pathology of pulmonary hypertension; clinical trial design in pulmonary hypertension

Molecular and signaling mechanisms of synaptic plasticity in memory formation and mental health