Pediatrics / Steiner Lab / Publications Publications McGrath KEKoniski ADMurphy KGetman MAn HHSchulz VPKim ARZhang BSchofield TLPapoin JBlanc LKingsley PDWesthoff CMGallagher PGChou STSteiner LAPalis J BMI1 regulates human erythroid self-renewal through both gene repression and gene activation.; bioRxiv : the preprint server for biology. 2024 Feb 06. Lv XMurphy KMurphy ZGetman MRRahman NFNakamura YBlanc LGallagher PGPalis JMohandas NSteiner LA HEXIM1 is an Essential Transcription Regulator During Human Erythropoiesis.; Blood. 2023 Sep 22. Papoin JYan HLeduc MLe Gall MNarla APalis JSteiner LAGallagher PGHillyer CDGautier EFMohandas NBlanc L Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways.; American journal of hematology. 2023 Jan 06. Guo BFriedland SCAlexander WMyers JAWang WO'Dell MRGetman MWhitney-Miller CLAgostini-Vulaj DHuber ARMello SSVertino PMLand HKSteiner LAHezel AF Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma.; Cell reports; Vol 40(9), pp. 111253. 2022 Aug 30. Michard FThiele RHSaugel BJoosten AFlick MKhanna AK Wireless wearables for postoperative surveillance on surgical wards: a survey of 1158 anaesthesiologists in Western Europe and the USA.; BJA open; Vol 1, pp. 100002. 2022 Feb 23. Dulmovits BMTang YPapoin JHe MLi JYang HAddorisio MEKennedy LKhan MBrindley ECAshley RJAckert-Bicknell CHale JKurita RKNakamura YDiamond BBarnes BJHermine OGallagher PGSteiner LALipton JMTaylor NMohandas NAndersson UAl-Abed YTracey KJBlanc L HMGB1-Mediated Restriction of EPO Signaling Contributes to Anemia of Inflammation.; Blood. 2022 Jan 18. Alkhunaizi EMartin NJelin ACRosner MBailey DJSteiner LALakhani SJi WKatzman PJForster KRJarinova OShannon PChitayat D Fetal akinesia deformation sequence syndrome associated with recessive TTN variants.; American journal of medical genetics. Part A. 2022 Jan 10. Murphy ZMurphy KMyers JAGetman MRCouch TSchulz VLezon-Geyda KPalumbo CYan HNarla MGallagher PGSteiner LA Regulation of RNA Polymerase II Activity is Essential for Terminal Erythroid Maturation.; Blood. 2021 Jun 01. Murphy ZCGetman MRMyers JAVillar KNBLeshen EKurita RNakamura YSteiner LA Codanin-1 Mutations Engineered in Human Erythroid Cells Demonstrate Role of CDAN1 in Terminal Erythroid Maturation.; Experimental hematology. 2020 Oct 16. Myers JACouch TMurphy ZMalik JGetman MSteiner LA The histone methyltransferase Setd8 alters the chromatin landscape and regulates the expression of key transcription factors during erythroid differentiation.; Epigenetics & chromatin; Vol 13(1). 2020 Mar 16. Steiner LAGetman MSchiralli Lester GMIqbal MAKatzman PSzafranski PStankiewicz PBhattacharya SMariani TPryhuber GLin XYoung JLDean DAScheible K Disruption of normal patterns of FOXF1 expression in a lethal disorder of lung development.; Journal of medical genetics. 2019 Oct 29. Couch TMurphy ZGetman MKurita RNakamura YSteiner LA Human Erythroblasts with c-Kit Activating Mutations Have Reduced Cell Culture Costs and Remain Capable of Terminal Maturation.; Experimental hematology. 2019 Apr 17. Wang WFriedland SCGuo BO'Dell MRAlexander WBWhitney-Miller CLAgostini-Vulaj DHuber ARMyers JRAshton JMDunne RFSteiner LAHezel AF ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas.; Gut. 2018 Sep 18. Malik JLillis JACouch TGetman MSteiner LA The Methyltransferase Setd8 Is Essential for Erythroblast Survival and Maturation.; Cell reports; Vol 21(9). 2017 Nov 28. Li YSchulz VPDeng CLi GShen YTusi BKMa GStees JQiu YSteiner LAZhou LZhao KBungert JGallagher PGHuang S Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation.; Nucleic acids research. 2016 May 3. Steiner LASchulz VMakismova YLezon-Geyda KGallagher PG CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells.; PloS one; Vol 11(5). 2016. Malik JGetman MSteiner LA Histone methyltransferase Setd8 represses Gata2 expression and regulates erythroid maturation.; Molecular and cellular biology; Vol 35(12). 2015 Jun. Getman MEngland SJMalik JPeterson KPalis JSteiner LA Extensively self-renewing erythroblasts derived from transgenic β-yac mice is a novel model system for studying globin switching and erythroid maturation.; Experimental hematology; Vol 42(7). 2014 Jul. Su MYSteiner LABogardus HMishra TSchulz VPHardison RCGallagher PG Identification of biologically relevant enhancers in human erythroid cells.; The Journal of biological chemistry; Vol 288(12). 2013 Mar 22. Yocum AOSteiner LASeidel NECline APRout EDLin JYWong CGarrett LJGallagher PGBodine DM A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter.; Blood; Vol 120(17). 2012 Oct 25. Steiner LASchulz VPMaksimova YWong CGallagher PG Patterns of histone H3 lysine 27 monomethylation and erythroid cell type-specific gene expression.; The Journal of biological chemistry; Vol 286(45). 2011 Nov 11. Pilon AMAjay SSKumar SASteiner LACherukuri PFWincovitch SAnderson SMMullikin JCGallagher PGHardison RCMargulies EHBodine DM Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation.; Blood; Vol 118(17). 2011 Oct 27. Li XWang SLi YDeng CSteiner LAXiao HWu CBungert JGallagher PGFelsenfeld GQiu YHuang S Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.; Blood; Vol 118(5). 2011 Aug 4. Hopewell BSteiner LAEhrenkranz RABizzarro MJGallagher PG Partial exchange transfusion for polycythemia hyperviscosity syndrome.; American journal of perinatology; Vol 28(7). 2011 Aug. Steiner LAEhrenkranz RAPeterec SMSteiner RDReyes-Múgica MGallagher PG Perinatal onset mevalonate kinase deficiency.; Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society; Vol 14(4). 2011 Jul. Gallagher PGSteiner LALiem RIOwen ANCline APSeidel NEGarrett LJBodine DM Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis.; The Journal of clinical investigation; Vol 120(12). 2010 Dec. Laflamme KOwen ANDevlin EEYang MQWong CSteiner LAGarrett LJElnitski LGallagher PGBodine DM Functional analysis of a novel cis-acting regulatory region within the human ankyrin gene (ANK-1) promoter.; Molecular and cellular biology; Vol 30(14). 2010 Jul. Steiner LAMaksimova YSchulz VWong CRaha DMahajan MCWeissman SMGallagher PG Chromatin architecture and transcription factor binding regulate expression of erythrocyte membrane protein genes.; Molecular and cellular biology; Vol 29(20). 2009 Oct. Di Terlizzi RGallagher PGMohandas NSteiner LADolce KSGuo XWilkerson MJStockham SL Canine elliptocytosis due to a mutant beta-spectrin.; Veterinary clinical pathology / American Society for Veterinary Clinical Pathology; Vol 38(1). 2009 Mar. Gallagher PGNilson DGSteiner LAMaksimova YDLin JYBodine DM An insulator with barrier-element activity promotes alpha-spectrin gene expression in erythroid cells.; Blood; Vol 113(7). 2009 Feb 12. Steiner LAGallagher PG Erythrocyte disorders in the perinatal period.; Seminars in perinatology; Vol 31(4). 2007 Aug. Steiner LABizzarro MJEhrenkranz RAGallagher PG A decline in the frequency of neonatal exchange transfusions and its effect on exchange-related morbidity and mortality.; Pediatrics; Vol 120(1). 2007 Jul. Steiner LAVan Hoff JKutlar FGallagher PG Aplastic crisis revealing the diagnosis of Hb Evans [alpha62(E11)Val-->Met, GTG-->ATG (alpha2)] in a Hispanic kindred: case report and review.; Hemoglobin; Vol 31(4). 2007.