Publications

• 1. Fowell DJ
  2. Kim M
  The spatio-temporal control of effector T cell migration.; Nature reviews. Immunology. 2021 Feb 24.
• 1. Bares AJ
  2. Mejooli MA
  3. Pender MA
  4. Leddon SA
  5. Tilley S
  6. Lin K
  7. Dong J
  8. Kim M
  9. Fowell DJ
  10. Nishimura N
  11. Schaffer CB
  Hyperspectral multiphoton microscopy for in vivo visualization of multiple, spectrally overlapped fluorescent labels.; Optica; Vol 7(11). 2020 Nov 20.
• 1. Lim K
  2. Kim TH
  3. Trzeciak A
  4. Amitrano AM
  5. Reilly EC
  6. Prizant H
  7. Fowell DJ
  8. Topham DJ
  9. Kim M
  In situ neutrophil efferocytosis shapes T cell immunity to influenza infection.; Nature immunology. 2020 Aug 03.
• 1. Fernandes NRJ
  2. Reilly NS
  3. Schrock DC
  4. Hocking DC
  5. Oakes PW
  6. Fowell DJ
  CD4+ T Cell Interstitial Migration Controlled by Fibronectin in the Inflamed Skin.; Frontiers in immunology; Vol 11. 2020.
• 1. Gaylo-Moynihan A
  2. Prizant H
  3. Popović M
  4. Fernandes NRJ
  5. Anderson CS
  6. Chiou KK
  7. Bell H
  8. Schrock DC
  9. Schumacher J
  10. Capece T
  11. Walling BL
  12. Topham DJ
  13. Miller J
  14. Smrcka AV
  15. Kim M
  16. Hughson A
  17. Fowell DJ
  Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites.; Immunity. 2019 Jul 31.
• 1. Schrock DC
  2. Leddon SA
  3. Hughson A
  4. Miller J
  5. Lacy-Hulbert A
  6. Fowell DJ
  Pivotal role for αV integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation.; Proceedings of the National Academy of Sciences of the United States of America. 2019 Feb 15.
• 1. Batchu SN
  2. Dugbartey GJ
  3. Wadosky KM
  4. Mickelsen DM
  5. Ko KA
  6. Wood RW
  7. Zhao Y
  8. Yang X
  9. Fowell DJ
  10. Korshunov VA
  Innate Immune Cells Are Regulated by Axl in Hypertensive Kidney.; The American journal of pathology; Vol 188(8). 2018 Aug.
• 1. Oakes PW
  2. Fowell DJ
  CCR7 fuels and LFA-1 grips.; Nature immunology; Vol 19(6). 2018 Jun.
• 1. Ford J
  2. Hughson A
  3. Lim K
  4. Bardina SV
  5. Lu W
  6. Charo IF
  7. Lim JK
  8. Fowell DJ
  CCL7 Is a Negative Regulator of Cutaneous Inflammation Following Leishmania major Infection.; Frontiers in immunology; Vol 9. 2018.
• 1. Meli AP
  2. Fontés G
  3. Avery DT
  4. Leddon SA
  5. Tam M
  6. Elliot M
  7. Ballesteros-Tato A
  8. Miller J
  9. Stevenson MM
  10. Fowell DJ
  11. Tangye SG
  12. King IL
  The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance.; Immunity; Vol 45(4). 2016 Oct 18.
• 1. Lambert Emo K
  2. Hyun YM
  3. Reilly E
  4. Barilla C
  5. Gerber S
  6. Fowell D
  7. Kim M
  8. Topham DJ
  Live Imaging of Influenza Infection of the Trachea Reveals Dynamic Regulation of CD8+ T Cell Motility by Antigen.; PLoS pathogens; Vol 12(9). 2016 Sep.
• 1. Billroth-MacLurg AC
  2. Ford J
  3. Rosenberg A
  4. Miller J
  5. Fowell DJ
  Regulatory T Cell Numbers in Inflamed Skin Are Controlled by Local Inflammatory Cues That Upregulate CD25 and Facilitate Antigen-Driven Local Proliferation.; Journal of immunology (Baltimore, Md. : 1950). 2016 Aug 10.
• 1. Batchu SN
  2. Hughson A
  3. Wadosky KM
  4. Morrell CN
  5. Fowell DJ
  6. Korshunov VA
  Role of Axl in T-Lymphocyte Survival in Salt-Dependent Hypertension.; Arteriosclerosis, thrombosis, and vascular biology. 2016 Jun 30.
• 1. Gaylo A
  2. Schrock DC
  3. Fernandes NR
  4. Fowell DJ
  T Cell Interstitial Migration: Motility Cues from the Inflamed Tissue for Micro- and Macro-Positioning.; Frontiers in immunology; Vol 7. 2016.
• 1. Gaylo A
  2. Overstreet MG
  3. Fowell DJ
  Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis.; Journal of visualized experiments : JoVE. 2016.
• 1. Misra R
  2. Shah S
  3. Fowell D
  4. Wang H
  5. Scheible K
  6. Misra S
  7. Huyck H
  8. Wyman C
  9. Ryan RM
  10. Reynolds AM
  11. Mariani T
  12. Katzman PJ
  13. Pryhuber GS
  Preterm cord blood CD4⁺ T cells exhibit increased IL-6 production in chorioamnionitis and decreased CD4⁺ T cells in bronchopulmonary dysplasia.; Human immunology; Vol 76(5). 2015 May.
• 1. Shi G
  2. Field DJ
  3. Ko KA
  4. Ture S
  5. Srivastava K
  6. Levy S
  7. Kowalska MA
  8. Poncz M
  9. Fowell DJ
  10. Morrell CN
  Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection.; The Journal of clinical investigation; Vol 124(2). 2014 Feb.
• 1. Overstreet MG
  2. Gaylo A
  3. Angermann BR
  4. Hughson A
  5. Hyun YM
  6. Lambert K
  7. Acharya M
  8. Billroth-Maclurg AC
  9. Rosenberg AF
  10. Topham DJ
  11. Yagita H
  12. Kim M
  13. Lacy-Hulbert A
  14. Meier-Schellersheim M
  15. Fowell DJ
  Inflammation-induced interstitial migration of effector CD4⁺ T cells is dependent on integrin αV.; Nature immunology; Vol 14(9). 2013 Sep.
• 1. Batchu SN
  2. Hughson A
  3. Gerloff J
  4. Fowell DJ
  5. Korshunov VA
  Role of Axl in early kidney inflammation and progression of salt-dependent hypertension.; Hypertension; Vol 62(2). 2013 Aug.
• 1. Lazarski CA
  2. Ford J
  3. Katzman SD
  4. Rosenberg AF
  5. Fowell DJ
  IL-4 attenuates Th1-associated chemokine expression and Th1 trafficking to inflamed tissues and limits pathogen clearance.; PloS one; Vol 8(8). 2013.
• 1. Hyun YM
  2. Sumagin R
  3. Sarangi PP
  4. Lomakina E
  5. Overstreet MG
  6. Baker CM
  7. Fowell DJ
  8. Waugh RE
  9. Sarelius IH
  10. Kim M
  Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels.; The Journal of experimental medicine; Vol 209(7). 2012 Jul 2.
• 1. Huang YH
  2. Sojka DK
  3. Fowell DJ
  Cutting edge: Regulatory T cells selectively attenuate, not terminate, T cell signaling by disrupting NF-κB nuclear accumulation in CD4 T cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 188(3). 2012 Feb 1.
• 1. Mock DJ
  2. Hollenbaugh JA
  3. Daddacha W
  4. Overstreet MG
  5. Lazarski CA
  6. Fowell DJ
  7. Kim B
  Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection.; PLoS pathogens; Vol 8(4). 2012.
• 1. Sojka DK
  2. Fowell DJ
  Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10.; Proceedings of the National Academy of Sciences of the United States of America; Vol 108(45). 2011 Nov 8.
• 1. Singleton KL
  2. Gosh M
  3. Dandekar RD
  4. Au-Yeung BB
  5. Ksionda O
  6. Tybulewicz VL
  7. Altman A
  8. Fowell DJ
  9. Wülfing C
  Itk controls the spatiotemporal organization of T cell activation.; Science signaling; Vol 4(193). 2011 Oct 4.
• 1. Hughson A
  2. Bromberg I
  3. Johnson B
  4. Quataert S
  5. Jospe N
  6. Fowell DJ
  Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes.; Diabetes; Vol 60(8). 2011 Aug.
• 1. Morales-Tirado V
  2. Sojka DK
  3. Katzman SD
  4. Lazarski CA
  5. Finkelman FD
  6. Urban JF
  7. Fowell DJ
  Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function.; Blood; Vol 115(17). 2010 Apr 29.
• 1. Sahu N
  2. Morales JL
  3. Fowell D
  4. August A
  Modeling susceptibility versus resistance in allergic airway disease reveals regulation by Tec kinase Itk.; PloS one; Vol 5(6). 2010.
• 1. Sojka DK
  2. Lazarski CA
  3. Huang YH
  4. Bromberg I
  5. Hughson A
  6. Fowell DJ
  Regulation of immunity at tissue sites of inflammation.; Immunologic research; Vol 45(2-3). 2009 Dec.
• 1. Sojka DK
  2. Hughson A
  3. Fowell DJ
  CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation.; European journal of immunology; Vol 39(6). 2009 Jun.
• 1. Fowell DJ
  Signals for the execution of Th2 effector function.; Cytokine; Vol 46(1). 2009 Apr.
• 1. Lazarski CA
  2. Hughson A
  3. Sojka DK
  4. Fowell DJ
  Regulating Treg cells at sites of inflammation.; Immunity; Vol 29(4). 2008 Oct 17.
• 1. Sojka DK
  2. Huang YH
  3. Fowell DJ
  Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target.; Immunology; Vol 124(1). 2008 May.
• 1. Katzman SD
  2. Fowell DJ
  Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site.; The Journal of clinical investigation; Vol 118(2). 2008 Feb.
• 1. Zhao X
  2. Zheng B
  3. Huang Y
  4. Yang D
  5. Katzman S
  6. Chang C
  7. Fowell D
  8. Zeng WP
  Interaction between GATA-3 and the transcriptional coregulator Pias1 is important for the regulation of Th2 immune responses.; Journal of immunology (Baltimore, Md. : 1950); Vol 179(12). 2007 Dec 15.
• 1. Au-Yeung BB
  2. Fowell DJ
  A key role for Itk in both IFN gamma and IL-4 production by NKT cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 179(1). 2007 Jul 1.
• 1. Sukiennicki TL
  2. Fowell DJ
  Distinct molecular program imposed on CD4+ T cell targets by CD4+CD25+ regulatory T cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 177(10). 2006 Nov 15.
• 1. Kobie JJ
  2. Shah PR
  3. Yang L
  4. Rebhahn JA
  5. Fowell DJ
  6. Mosmann TR
  T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine.; Journal of immunology (Baltimore, Md. : 1950); Vol 177(10). 2006 Nov 15.
• 1. Au-Yeung BB
  2. Katzman SD
  3. Fowell DJ
  Cutting edge: Itk-dependent signals required for CD4+ T cells to exert, but not gain, Th2 effector function.; Journal of immunology (Baltimore, Md. : 1950); Vol 176(7). 2006 Apr 1.
• 1. Sojka DK
  2. Hughson A
  3. Sukiennicki TL
  4. Fowell DJ
  Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity.; Journal of immunology (Baltimore, Md. : 1950); Vol 175(11). 2005 Dec 1.
• 1. Morales-Tirado V
  2. Johannson S
  3. Hanson E
  4. Howell A
  5. Zhang J
  6. Siminovitch KA
  7. Fowell DJ
  Cutting edge: selective requirement for the Wiskott-Aldrich syndrome protein in cytokine, but not chemokine, secretion by CD4+ T cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 173(2). 2004 Jul 15.
• 1. Gurunathan S
  2. Stobie L
  3. Prussin C
  4. Sacks DL
  5. Glaichenhaus N
  6. Iwasaki A
  7. Fowell DJ
  8. Locksley RM
  9. Chang JT
  10. Wu CY
  11. Seder RA
  Requirements for the maintenance of Th1 immunity in vivo following DNA vaccination: a potential immunoregulatory role for CD8+ T cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 165(2). 2000 Jul 15.
• 1. Pippig SD
  2. Peña-Rossi C
  3. Long J
  4. Godfrey WR
  5. Fowell DJ
  6. Reiner SL
  7. Birkeland ML
  8. Locksley RM
  9. Barclay AN
  10. Killeen N
  Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40).; Journal of immunology (Baltimore, Md. : 1950); Vol 163(12). 1999 Dec 15.
• 1. Heath VL
  2. Hutchings P
  3. Fowell DJ
  4. Cooke A
  5. Mason DW
  Peptides derived from murine insulin are diabetogenic in both rats and mice, but the disease-inducing epitopes are different: evidence against a common environmental cross-reactivity in the pathogenicity of type 1 diabetes.; Diabetes; Vol 48(11). 1999 Nov.
• 1. Fowell DJ
  2. Shinkai K
  3. Liao XC
  4. Beebe AM
  5. Coffman RL
  6. Littman DR
  7. Locksley RM
  Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells.; Immunity; Vol 11(4). 1999 Oct.
• 1. Fowell DJ
  2. Locksley RM
  Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases.; BioEssays : news and reviews in molecular, cellular and developmental biology; Vol 21(6). 1999 Jun.
• 1. Pingel S
  2. Launois P
  3. Fowell DJ
  4. Turck CW
  5. Southwood S
  6. Sette A
  7. Glaichenhaus N
  8. Louis JA
  9. Locksley RM
  Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope.; The Journal of experimental medicine; Vol 189(7). 1999 Apr 5.
• 1. Locksley RM
  2. Pingel S
  3. Lacy D
  4. Wakil AE
  5. Bix M
  6. Fowell DJ
  Susceptibility to infectious diseases: Leishmania as a paradigm.; The Journal of infectious diseases; Vol 179 Suppl 2. 1999 Mar.
• 1. Wakil AE
  2. Wang ZE
  3. Ryan JC
  4. Fowell DJ
  5. Locksley RM
  Interferon gamma derived from CD4(+) T cells is sufficient to mediate T helper cell type 1 development.; The Journal of experimental medicine; Vol 188(9). 1998 Nov 2.
• 1. Fowell DJ
  2. Bix M
  3. Shinkai K
  4. Lacy D
  5. Locksley RM
  Disease susceptibility and development of the cytokine repertoire in the murine Leishmania major model.; European cytokine network; Vol 9(3 Suppl). 1998 Sep.