Faculty
Signaling transduction mechanisms in the vascular system
Epidemiology and pathogenesis of respiratory viruses (influenza, RSV, COVID). Vaccine development. Immunology.
Defining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders.
Environmental epidemiology on the effect of air pollution on respiratory health
Toxicology of inhaled particulate matter on the lung, cardiovascular, and central nervous systems
Understanding the pathogenesis of Acute Lung Injury (ALI), a life threatening pulmonary inflammatory condition
Defining molecular pathways by which inhaled allergens and particulates activate lung mucosal immunity.
Effect of lifestyle, human milk, and infant microbiome of development of immune system and allergic diseases.
Cancer immunotherapy/Host immune response to influenza infection/ Inflammation biology of sepsis
Cellular and molecular mechanisms of lung fibrosis; new treatments for interstitial lung diseases
Improve and provide access to care for patients with pulmonary vascular disease
Defining the impact of environmental exposures on immune system development and function, with emphasis on how early life exposures shape health and disease later in life.
Investigates prenatal and early life nutritional and environmental exposures that impact the development of asthma and affect lung growth.
Genetic and environmental susceptibility to developmental lung injury.
In vitro models of human lung and vascular barriers during inflammation.
Airway epithelial stem cells in chemical inhalation exposures.
Platelets in vascular injury and inflammation
Defining how gene environment interactions shape alveolar lung development and the risk for lung disease over the lifespan.
Team approaches to patient-centered, clinical and translational investigation in sepsis and critical illness
Multiple molecular modality identification of lung cell types, subtypes and states in health and disease with focus on diseases of children.
The mechanisms of lung vascular endothelial cell dysfunction in acute lung injury
Environmental lung diseases COPD and IPF pathogenesis and therapeutic targets: effects of lung cellular mitochondrial dysfunction, senescence, and molecular clock.
Cardiovascular, respiratory, and pregnancy health effects of exposure to environmental agents, including ambient air pollution; accountability studies.
Early detection of lung cancer, toxicities caused by therapies in lung cancer, and the prevalence of lung cancer in women
Innate cell antiviral responses, allergic inflammation, mucosal/airway immunity, vaccine responses
Specificity and role of CD4 T cells in response to vaccination and infection
Molecular determinants of and clinical outcomes related to normal and abnormal development of the adaptive immune system in human infants.
Cellular and molecular mechanisms of heart development, disease, and regeneration; Transcriptional regulation of fibroblast plasticity and cardiac fibrosis
Environmental health applications, models for multiple outcomes, multiple exposure models, measurement error, Bayesian inference.
Immune responses to respiratory viruses and experimental vaccines
Thrombosis and platelet activation in vascular pathology of pulmonary hypertension; clinical trial design in pulmonary hypertension