Faculty

Anolik Lab

Astapova Lab

Investigating insulin signaling in the polycystic ovarian syndrome (PCOS) ovary and the role of dietary advanced glycation end-products in PCOS using a mouse model of this syndrome. My clinical interest is in managing the symptoms and reducing the metabolic risks associated with PCOS, as well as managing other conditions of disordered sex steroids.

Calvi Lab

Cory-Slechta Lab

Defining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders. 

DeLouise Lab

Nanomaterial and microplastic toxicology focused on the skin; develop novel microphysiologic tissue chips for drug discovery and toxicity testing; investigate environmental pollutants in autoimmune disease.

Dean Lab

Elder Lab

Toxicology of inhaled particulate matter on the lung, cardiovascular, and central nervous systems

Fazal Lab

Understanding the pathogenesis of Acute Lung Injury (ALI), a life threatening pulmonary inflammatory condition

Georas Lab

Program for Advanced Immune Bioimaging

Defining molecular pathways by which inhaled allergens and particulates activate lung mucosal immunity.

Rochester Environment and Child Health (REACH) Laboratory

Defining the impact of environmental toxicants on maternal and child health, with a focus on persistent organic pollutants (PCBs and PFAS), metals, and their mixtures, and immune system development and function.

Järvinen-Seppo Lab

Effect of lifestyle, human milk, and infant microbiome of development of immune system and allergic diseases.

Kottmann Lab

Cellular and molecular mechanisms of lung fibrosis; new treatments for interstitial lung diseases

Lawrence Lab

Defining the impact of environmental exposures on immune system development and function, with emphasis on how early life exposures shape health and disease later in life.

Majewska Lab

Glia-neuron interactions during synaptic plasticity in health and disease.

Mayer-Pröschel Lab

Impact of iron deficiency on brain development and interactions with environmental toxicants and genetic factors.

Patrick Murphy Lab

The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.

O'Banion-Olschowka Labs

Defining neuro-inflammatory processes that contribute to pathology and disease progression in Alzheimer's disease, as well as late CNS effects following radiation exposure.

Wynne Center for Family Research

The mechanisms by which early stress exposures, including prenatal maternal anxiety and caregiving stress, may persistently shape children's behavioral and biological health.

O'Reilly Lab

Defining how gene environment interactions shape alveolar lung development and the risk for lung disease over the lifespan.

Onukwufor Lab

Mitochondrial Research and Innovation Group

Elucidate the molecular mechanisms of divalent metal neurotoxicity and mitochondrial dysfunction in Alzheimer's disease pathogenesis.

Pryhuber Lab

Multiple molecular modality identification of lung cell types, subtypes and states in health and disease with focus on diseases of children.

Pröschel Lab

Using primarily human pluripotent stem cell models, we examine astrocyte development in normal and pathological conditions, the role of astrocytes in modulating response to injury or stress, the role of altered RNA processing and translation in neural development, and the utility of glial precursor cells and their astrocytic progeny for cell transplantation therapy.

Arshad Rahman Lab

The mechanisms of lung vascular endothelial cell dysfunction in acute lung injury

Irfan Rahman Lab

Environmental lung diseases COPD and IPF pathogenesis and therapeutic targets: effects of lung cellular mitochondrial dysfunction, senescence, and molecular clock.

Rand Lab

Cellular and molecular mechanisms of methylmercury metabolism and toxicity in development of neural and muscular systems using invertebrate, mammalian and human models.

Rich Lab

Cardiovascular, respiratory, and pregnancy health effects of exposure to environmental agents, including ambient air pollution; accountability studies.

Robert Lab

Experimental platform using the amphibian Xenopus for research in immunotoxicology, fundamental and medical immunology.

Rowe Lab

Innate cell antiviral responses, allergic inflammation, mucosal/airway immunity, vaccine responses

Sarkar Lab

Develop a research program concentrating on identifying genetic modifiers of environmental factors in disease etiology using a combination of Drosophila genetics, cell culture, and rodent models.

Sobolewski Lab

Neurotoxicology, behavioral analysis, endocrine-epigenetic mechanisms, cumulative risk.

Susiarjo Lab

Exploring the mechanisms underlying gene-environment interactions in pregnancy; exploring the role of tryptophan catabolism in pregnancy and on the metabolic health of mother and offspring.

Program for Advanced Immune Bioimaging

Topham Lab

Immune responses to respiratory viruses and experimental vaccines

Wojtovich Lab

Mitochondrial Research and Innovation Group

Xia Lab

Molecular and signaling mechanisms of synaptic plasticity in memory formation and mental health

VanWijngaarden Lab

Environmental and nutritional influences on cognitive and neurodevelopmental outcomes.