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Biochemistry PhD Program

Education / Graduate Education / PhD Programs / Biochemistry & Molecular Biology / Faculty & Students / Faculty

 

Faculty

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Affiliated Faculty

Brian Altman, Ph.D.
Brian Altman, Ph.D.

Altman Lab

Biomedical Genetics
Research Interest:

Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism. 


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Xin Bi, Ph.D.
Xin Bi, Ph.D.

Bi Lab

Biology
Research Interest: Chromatin-mediated regulation of gene expression in eukaryotes.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Paul Boutz, Ph.D.
Paul Boutz, Ph.D.

Boutz Lab

Biochemistry & Biophysics
Research Interest: Regulation of pre-mRNA splicing and polyadenylation in healthy and diseased states; the contribution of RNA processing to cancer biology; effects of small molecule drugs on RNA processing and gene expression.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Paul Brookes, Ph.D.
Paul Brookes, Ph.D.

Brookes Lab

Mitochondrial Research and Innovation Group

Anesthesiology and Perioperative Medicine
Pharmacology & Physiology
Research Interest: Cardioprotection against ischemia-reperfusion (IR) injury. Role of Mitochondria and metabolism in ischemic preconditioning and anesthetic preconditioning.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Michael Bulger, Ph.D.
Michael Bulger, Ph.D.

Bulger Lab

Pediatrics
Biochemistry & Biophysics
Research Interest: Chromatin domains and long-range activation by enhancers

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Gloria Culver, Ph.D.
Gloria Culver, Ph.D.

Culver Lab

Biology
Biochemistry & Biophysics
Research Interest: Assembly of the E. coli 30S ribosomal subunit, which is essential for cellular growth, so as to understand how infections might be controlled through selective inhibition of specific assembly control points.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Ian Dickerson, Ph.D.
Ian Dickerson, Ph.D.

Dickerson Lab

Pharmacology & Physiology
Neuroscience
Biomedical Engineering
Research Interest: Molecular mechanisms of neuropeptide signal transduction

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Mark Dumont, Ph.D.
Mark Dumont, Ph.D.

Dumont Lab

Pediatrics
Biochemistry & Biophysics
Research Interest: Signal transduction; membrane protein structure, yeast molecular biology

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Dmitri Ermolenko, Ph.D.
Dmitri Ermolenko, Ph.D.

Ermolenko Lab

Biology
Biochemistry & Biophysics
Research Interest:

Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Sina Ghaemmaghami, Ph.D.
Sina Ghaemmaghami, Ph.D.

Ghaemmaghami Lab

Biology
Research Interest: Molecular mechanisms of prion propagation and pathogenesis

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Vera Gorbunova, Ph.D.
Vera Gorbunova, Ph.D.

Gorbunova & Seluanov Lab

Biology
Research Interest:

Mechanisms of aging and the role of DNA repair and genomic instability in the aging process.


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Elizabeth Grayhack, Ph.D.
Elizabeth Grayhack, Ph.D.

Grayhack Lab

Biochemistry & Biophysics
Research Interest: Role of the genetic code in regulating protein synthesis and mRNA metabolism in Saccharomyces cerevisiae.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Alan Grossfield, Ph.D.
Alan Grossfield, Ph.D.

Grossfield Lab

Biochemistry & Biophysics
Research Interest:

Investigating membranes and membrane proteins via computer simulation


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Isaac Harris, Ph.D.
Isaac Harris, Ph.D.

Harris Lab

Mitochondrial Research and Innovation Group

Biomedical Genetics
Research Interest:

Understanding the roles of antioxidants in disease


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Jeffrey Hayes, Ph.D.
Jeffrey Hayes, Ph.D.
Director

William A. Bernhard Memorial Lab

Hayes Lab

Biochemistry & Biophysics
Research Interest: Regulation of transcription, nuclear processes, related to chromatin structure and function

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Clara Kielkopf, Ph.D.
Clara Kielkopf, Ph.D.

Kielkopf Lab

Biochemistry & Biophysics
Research Interest: Splicing defects in hematologic malignancies; roles of human pre-mRNA splicing factors in HIV-1 infectivity; development of engineered splicing factors for correction of splicing defects; splice sites and their associated proteins as therapeutic targets.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Hartmut Land, Ph.D.
Hartmut Land, Ph.D.

Land Lab

Biochemistry & Biophysics
Biomedical Genetics
Research Interest: Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell Metabolism

Mentor for Biochemistry & Molecular Biology Ph.D. Program
John Lueck, Ph.D.
John Lueck, Ph.D.

Lueck Lab

Pharmacology & Physiology
Neurology
Research Interest: Determining the therapeutic promise of engineered tRNAs for treatment of nonsense associated diseases and investigating the pathomechanisms of skeletal muscle weakness and wasting in myotonic dystrophy

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Lynne Maquat, Ph.D.
Lynne Maquat, Ph.D.

Maquat Lab

Biochemistry & Biophysics
Research Interest:

RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases.


Mentor for Biochemistry & Molecular Biology Ph.D. Program
David Mathews, M.D., Ph.D.
David Mathews, M.D., Ph.D.

Mathews Lab

Biochemistry & Biophysics
Research Interest: Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Margot Mayer-Pröschel, Ph.D.
Margot Mayer-Pröschel, Ph.D.

Mayer-Pröschel Lab

Neuroscience
Biomedical Genetics
Research Interest: Identification of different stem and precursor cell pools in CNS that may be critical for cell replacement therapies or are targets of insults that lead to developmental pathologies.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Stephano Mello, Ph.D.
Stephano Mello, Ph.D.

Mello Lab

Biomedical Genetics
Research Interest: Understanding how nuclear proteins and non-coding RNAs (ncRNAs) regulate gene transcription in pancreatic preneoplastic lesions, gaining knowledge of the process of cellular transformation and tumor initiation.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Anne Meyer, Ph.D.
Anne Meyer, Ph.D.

Meyer Lab

Biology
Research Interest: Bacterial stress response; 3D Printing of Bacteria; Biomaterials

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Benjamin Miller, Ph.D.
Benjamin Miller, Ph.D.

Benjamin Miller Lab

Biochemistry & Biophysics
Biomedical Engineering
Dermatology
Research Interest:

Carbohydrate and protein recognition, molecular design, and biomolecular sensing


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Joshua Munger, Ph.D.
Joshua Munger, Ph.D.
Director

Munger Lab

Biochemistry & Biophysics
Microbiology & Immunology
Research Interest: Mechanisms of metabolic network manipulation induced by viral infection and oncogenic mutation.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Patrick Murphy, Ph.D.
Patrick Murphy, Ph.D.

Patrick Murphy Lab

Biomedical Genetics
Research Interest:

The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Mitchell O'Connell, Ph.D.
Mitchell O'Connell, Ph.D.

O'Connell Lab

Biochemistry & Biophysics
Research Interest: Biochemical mechanisms of RNA-mediated gene regulation; RNA-targeting CRISPR tool development

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Eric Phizicky, Ph.D.
Eric Phizicky, Ph.D.

Phizicky Lab

Biochemistry & Biophysics
Research Interest: tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Marlies Rossmann, M.D., Ph.D.
Marlies Rossmann, M.D., Ph.D.

Rossmann Lab

Mitochondrial Research and Innovation Group

Biomedical Genetics
Microbiology & Immunology
Research Interest:

The role of metabolism in lineage differentiation


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Elaine Sia, Ph.D.
Elaine Sia, Ph.D.

Sia Lab

Biology
Research Interest: Mutagenesis and repair of the mitochondrial genome.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Laurie Steiner, M.D.
Laurie Steiner, M.D.

Steiner Lab

Pediatrics
Medicine
Research Interest:

Understanding how regulation of RNA Polymerase II activity regulates cellular differentiation, with a focus on erythropoiesis. Delineating epigenetic control of normal erythropoiesis; determining the contribution of disrupted epigenetic regulation to inherited anemias.


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Paula Vertino, Ph.D.
Paula Vertino, Ph.D.

Vertino Lab

Biomedical Genetics
Research Interest: Cancer epigenetics: the role of DNA methylation and chromatin in driving cancer phenotypes and as a target for therapeutic intervention

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Eric Wagner, Ph.D.
Eric Wagner, Ph.D.

Wagner Lab

Biochemistry & Biophysics
Research Interest:

Mechanism and physiological importance of alternative polyadenylation; Integrator Complex and transcriptional control, development and application of next-generation sequencing technologies


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Ning Wang, PhD
Ning Wang, PhD

Ning-Wang Lab

Biology
Research Interest:

Cell biology, biochemistry, and molecular genetics; Organelle biogenesis; Organelle degradation through selective autophagy; Organelle aging and neurodegeneration; Cellular stress response


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Joseph Wedekind, Ph.D.
Joseph Wedekind, Ph.D.

Wedekind Lab

Biochemistry & Biophysics
Research Interest: Structure and function analysis of gene regulation by non-protein-coding (nc)RNAs as a basis for therapeutic development.

Mentor for Biochemistry & Molecular Biology Ph.D. Program
Peng Yao, Ph.D.
Peng Yao, Ph.D.

Yao Lab

Mitochondrial Research and Innovation Group

Biochemistry & Biophysics
Medicine
Research Interest:

Pathophysiological function and molecular mechanism of new non-coding RNAs and RNA-binding proteins and translational control in cardiac system and cardiovascular disease


Mentor for Biochemistry & Molecular Biology Ph.D. Program
Yi-Tao Yu, Ph.D.
Yi-Tao Yu, Ph.D.

Yu Lab

Biochemistry & Biophysics
Research Interest: RNA modification; pre-mRNA splicing; snRNP biogenesis; telomerase RNA modification and aging; nonsense-disease therapeutics.

Mentor for Biochemistry & Molecular Biology Ph.D. Program