A022101 ERASur / CRGIC23031 / Alliance / QIU
Basic Study Information
Purpose:
This phase III trial compares total ablative therapy and usual systemic therapy to
usual systemic therapy alone in treating patients with colorectal cancer that has
spread to up to 4 body sites (limited metastatic). The usual approach for patients
who are not participating in a study is treatment with intravenous (IV) (through a
vein) and/or oral medications (systemic therapy) to help stop the cancer sites from
getting larger and the spread of the cancer to additional body sites. Ablative means
that the intention of the local treatment is to eliminate the cancer at that metastatic
site. The ablative local therapy will consist of very focused, intensive radiotherapy
called stereotactic ablative radiotherapy (SABR) with or without surgical resection
and/or microwave ablation, which is a procedure where a needle is temporarily inserted
in the tumor and heat is used to destroy the cancer cells. SABR, surgical resection,
and microwave ablation have been tested for safety, but it is not scientifically proven
that the addition of these treatments are beneficial for your stage of cancer. The
addition of ablative local therapy to all known metastatic sites to the usual approach
of systemic therapy could shrink or remove the tumor(s) or prevent the tumor(s) from
returning.
Location: University of Rochester
Lead Researcher (Principal Investigator)
Lead Researcher:
Haoming Qiu
Study Contact Information
Study Contact: Clinical Trials Office
Study Location: Wilmot Cancer Institute, University of Rochester Medical Center
Study Email: WCICTOResearch@urmc.rochester.edu
Additional Study Details
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