Pediatrics / Fazal Lab / Publications Publications Leonard ASu PYYule DIRahman AFazal F Critical Role of Mortalin/GRP75 In Endothelial Cell Dysfunction Associated With Acute Lung Injury.; Shock (Augusta, Ga.). 2019 Sep 04. Leonard AMillar MWSlavin SABijli KMDionisio Santos DADean DAFazal FRahman A Critical role of autophagy regulator Beclin1 in endothelial cell inflammation and barrier disruption.; Cellular signalling. 2019 May 01. Leonard AGrose VPaton AWPaton JCYule DIRahman AFazal F Selective Inactivation of Intracellular BiP/GRP78 Attenuates Endothelial Inflammation and Permeability in Acute Lung Injury.; Scientific reports; Vol 9(1). 2019 Feb 14. Leonard ARahman AFazal F Importins α and β signaling mediates endothelial cell inflammation and barrier disruption.; Cellular signalling. 2018 Jan 10. Jain SVKollisch-Singule MSatalin JSearles QDombert LAbdel-Razek OYepuri NLeonard AGruessner AAndrews PFazal FMeng QWang GGatto LAHabashi NMNieman GF The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model.; Intensive care medicine experimental; Vol 5(1). 2017 Dec. Slavin SALeonard AGrose VFazal FRahman A Autophagy Inhibitor 3-Methyladenine Protects against Endothelial Cell Barrier Dysfunction in Acute Lung Injury.; American journal of physiology. Lung cellular and molecular physiology. 2017 Oct 26. Barnett RCLin XBarravecchia MNorman RAde Mesy Bentley KLFazal FYoung JLDean DA Featured Article: Electroporation-mediated gene delivery of surfactant protein B (SP-B) restores expression and improves survival in mouse model of SP-B deficiency.; Experimental biology and medicine (Maywood, N.J.); Vol 242(13). 2017 Jul. Bijli KMFazal FSlavin SALeonard AGrose VAlexander WBSmrcka AVRahman A Phospholipase C Epsilon Signaling Mediates Endothelial Cell Inflammation and Barrier Disruption in Acute Lung Injury.; American journal of physiology. Lung cellular and molecular physiology. 2016 Jul 1. Bijli KMKanter BGMinhajuddin MLeonard AXu LFazal FRahman A Regulation of endothelial cell inflammation and lung polymorphonuclear lymphocyte infiltration by transglutaminase 2.; Shock (Augusta, Ga.); Vol 42(6). 2014 Dec. Leonard APaton AWEl-Quadi MPaton JCFazal F Preconditioning with endoplasmic reticulum stress ameliorates endothelial cell inflammation.; PloS one; Vol 9(10). 2014. Leonard AMarando CRahman AFazal F Thrombin selectively engages LIM kinase 1 and slingshot-1L phosphatase to regulate NF-κB activation and endothelial cell inflammation.; American journal of physiology. Lung cellular and molecular physiology; Vol 305(9). 2013 Nov 1. Fazal FBijli KMMurrill MLeonard AMinhajuddin MAnwar KNFinkelstein JNWatterson DMRahman A Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN infiltration.; PloS one; Vol 8(3). 2013. Bijli KMFazal FRahman A Regulation of Rela/p65 and endothelial cell inflammation by proline-rich tyrosine kinase 2.; American journal of respiratory cell and molecular biology; Vol 47(5). 2012 Nov. Rahman AFazal F Blocking NF-κB: an inflammatory issue.; Proceedings of the American Thoracic Society; Vol 8(6). 2011 Nov. Yang LChen GMohanty SScott GFazal FRahman ABegum SHynes ROXu L GPR56 Regulates VEGF production and angiogenesis during melanoma progression.; Cancer research; Vol 71(16). 2011 Aug 15. Fazal FBijli KMMinhajuddin MRein TFinkelstein JNRahman A Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells.; The Journal of biological chemistry; Vol 284(31). 2009 Jul 31. Rahman AFazal F Hug tightly and say goodbye: role of endothelial ICAM-1 in leukocyte transmigration.; Antioxidants & redox signaling; Vol 11(4). 2009 Apr. Minhajuddin MBijli KMFazal FSassano ANakayama KIHay NPlatanias LCRahman A Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells.; The Journal of biological chemistry; Vol 284(7). 2009 Feb 13. Bijli KMFazal FMinhajuddin MRahman A Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.; The Journal of biological chemistry; Vol 283(21). 2008 May 23. Fazal FMinhajuddin MBijli KMMcGrath JLRahman A Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells.; The Journal of biological chemistry; Vol 282(6). 2007 Feb 9. Bijli KMMinhajuddin MFazal FO'Reilly MAPlatanias LCRahman A c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.; American journal of physiology. Lung cellular and molecular physiology; Vol 292(2). 2007 Feb. Fazal FGu LIhnatovych IHan YHu WAntic NCarreira FBlomquist JFHope TJUcker DSde Lanerolle P Inhibiting myosin light chain kinase induces apoptosis in vitro and in vivo.; Molecular and cellular biology; Vol 25(14). 2005 Jul. Minhajuddin MFazal FBijli KMAmin MRRahman A Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 174(9). 2005 May 1. Anwar KNFazal FMalik ABRahman A RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65.; Journal of immunology (Baltimore, Md. : 1950); Vol 173(11). 2004 Dec 1. Nobe HNobe KFazal FDe Lanerolle PPaul RJ Rho kinase mediates serum-induced contraction in fibroblast fibers independent of myosin LC20 phosphorylation.; American journal of physiology. Cell physiology; Vol 284(3). 2003 Mar. Adami CPooley JGlomb JStecker EFazal FFleming JOBaker SC Evolution of mouse hepatitis virus (MHV) during chronic infection: quasispecies nature of the persisting MHV RNA.; Virology; Vol 209(2). 1995 Jun 01.