Publications

• 1. Zhang D
  2. Xu H
  3. Qin C
  4. Cai K
  5. Zhang J
  6. Xia X
  7. Bi J
  8. Zhang L
  9. Xing L
  10. Liang Q
  11. Wang W
  Reduced expression of semaphorin 3A in osteoclasts causes lymphatic expansion in a Gorham-Stout disease (GSD) mouse model.; Journal of Zhejiang University. Science. B; Vol 25(1), pp. 38-50. 2024 Jan 15.
• 1. Wang YJ
  2. Zheng Y
  3. Cong L
  4. Wang P
  5. Zhao L
  6. Xing L
  7. Liu J
  8. Xu H
  9. Li N
  10. Zhao Y
  11. Shi Q
  12. Liang Q
  Lymphatic platelet thrombosis limits bone repair by precluding lymphatic transporting DAMPs.; Research square. 2023 Jan 14.
• 1. Peng Y
  2. Kenney HM
  3. de Mesy Bentley KL
  4. Xing L
  5. Ritchlin CT
  6. Schwarz EM
  Distinct mast cell subpopulations within and around lymphatic vessels regulate lymph flow and progression of inflammatory-erosive arthritis in TNF-transgenic mice.; Frontiers in immunology; Vol 14, pp. 1275871. 2023 Jan 14.
• 1. Lin X
  2. Zhang H
  3. Liu J
  4. Wu CL
  5. McDavid A
  6. Boyce BF
  7. Xing L
  Aged Callus Skeletal Stem/Progenitor Cells Contain an Inflammatory Osteogenic Population With Increased IRF and NF-κB Pathways and Reduced Osteogenic Potential.; Frontiers in molecular biosciences; Vol 9. 2022.
• 1. Sun S
  2. Tao J
  3. Sedghizadeh PP
  4. Cherian P
  5. Junka AF
  6. Sodagar E
  7. Xing L
  8. Boeckman RK
  9. Srinivasan V
  10. Yao Z
  11. Boyce BF
  12. Lipe B
  13. Neighbors JD
  14. Russell G
  15. McKenna CE
  16. Ebetino FH
  Bisphosphonates for delivering drugs to bone.; British journal of pharmacology. 2020 Sep 02.
• 1. Wang H
  2. Chen Y
  3. Li W
  4. Sun L
  5. Chen H
  6. Yang Q
  7. Zhang H
  8. Zhang W
  9. Yuan H
  10. Zhang H
  11. Xing L
  12. Sun W
  Effect of VEGFC on lymph flow and inflammation-induced alveolar bone loss.; The Journal of pathology; Vol 251(3). 2020 Jul.
• 1. Yuan G
  2. Yang S
  3. Ng A
  4. Fu C
  5. Oursler MJ
  6. Xing L
  7. Yang S
  RGS12 Is a Novel Critical NF-κB Activator in Inflammatory Arthritis.; iScience; Vol 23(6). 2020 Jun 26.
• 1. Lin X
  2. Zhang H
  3. Boyce BF
  4. Xing L
  Ubiquitination of interleukin-1α is associated with increased pro-inflammatory polarization of murine macrophages deficient in the E3 ligase ITCH.; The Journal of biological chemistry. 2020 Jun 25.
• 1. Xing L
  2. Ebetino FH
  3. Boeckman RK
  4. Srinivasan V
  5. Tao J
  6. Sawyer TK
  7. Li J
  8. Yao Z
  9. Boyce BF
  Targeting anti-cancer agents to bone using bisphosphonates.; Bone. 2020 Jun 22.
• 1. Chen J
  2. Wang L
  3. Xu H
  4. Xing L
  5. Zhuang Z
  6. Zheng Y
  7. Li X
  8. Wang C
  9. Chen S
  10. Guo Z
  11. Liang Q
  12. Wang Y
  Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage.; Nature communications; Vol 11(1). 2020 Jun 22.
• 1. Li J
  2. Yi X
  3. Yao Z
  4. Chakkalakal JV
  5. Xing L
  6. Boyce BF
  TNF receptor-associated factor 6 mediates TNFα-induced skeletal muscle atrophy in mice during aging.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2020 Apr 08.
• 1. Bell RD
  2. Slattery PN
  3. Wu EK
  4. Xing L
  5. Ritchlin CT
  6. Schwarz EM
  iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis.; Arthritis research & therapy; Vol 21(1). 2019 Nov 14.
• 1. Wang H
  2. Zhang H
  3. Srinivasan V
  4. Tao J
  5. Sun W
  6. Lin X
  7. Wu T
  8. Boyce BF
  9. Ebetino FH
  10. Boeckman RK
  11. Xing L
  Targeting Bortezomib to Bone Increases its Bone Anabolic Activity and Reduces Systemic Adverse Effects in Mice.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2019 Oct 14.
• 1. Liang Q
  2. Zhang L
  3. Wood RW
  4. Ji RC
  5. Boyce BF
  6. Schwarz EM
  7. Wang Y
  8. Xing L
  RelB regulates lymphatic endothelial cells during vessel maturation and is required for lymphatic vessel function in adult mice.; The American journal of pathology. 2019 Sep 17.
• 1. Li J
  2. Ayoub A
  3. Xiu Y
  4. Yin X
  5. Sanders JO
  6. Mesfin A
  7. Xing L
  8. Yao Z
  9. Boyce BF
  TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.; Nature communications; Vol 10(1). 2019 Jun 26.
• 1. Sun W
  2. Meednu N
  3. Rosenberg A
  4. Rangel-Moreno J
  5. Wang V
  6. Glanzman J
  7. Owen T
  8. Zhou X
  9. Zhang H
  10. Boyce BF
  11. Anolik JH
  12. Xing L
  B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation.; Nature communications; Vol 9(1). 2018 Dec 03.
• 1. Ye H
  2. Adane B
  3. Khan N
  4. Alexeev E
  5. Nusbacher N
  6. Minhajuddin M
  7. Stevens BM
  8. Winters AC
  9. Lin X
  10. Ashton JM
  11. Purev E
  12. Xing L
  13. Pollyea DA
  14. Lozupone CA
  15. Serkova NJ
  16. Colgan SP
  17. Jordan CT
  Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells.; Cancer cell. 2018 Sep 18.
• 1. Wang H
  2. Xiao L
  3. Tao J
  4. Srinivasan V
  5. Boyce BF
  6. Ebetino FH
  7. Oyajobi BO
  8. Boeckman RK
  9. Xing L
  Synthesis of a Bone-Targeted Bortezomib with In Vivo Anti-Myeloma Effects in Mice.; Pharmaceutics; Vol 10(3). 2018 Sep 10.
• 1. Wang W
  2. Lin X
  3. Xu H
  4. Sun W
  5. Bouta EM
  6. Zuscik MJ
  7. Chen D
  8. Schwarz EM
  9. Xing L
  Bortezomib Attenuates Joint Tissue Damage in a Mouse Model of Experimental Post-Traumatic Osteoarthritis, which is Associated with Improved Synovial Lymphatic Function.; Arthritis & rheumatology (Hoboken, N.J.). 2018 Aug 25.
• 1. Paine A
  2. Woeller CF
  3. Zhang H
  4. de la Luz Garcia-Hernandez M
  5. Huertas N
  6. Xing L
  7. Phipps RP
  8. Ritchlin CT
  Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 32(6). 2018 Jun.
• 1. Bouta EM
  2. Bell RD
  3. Rahimi H
  4. Xing L
  5. Wood RW
  6. Bingham CO
  7. Ritchlin CT
  8. Schwarz EM
  Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis.; Nature reviews. Rheumatology; Vol 14(2). 2018 Feb.
• 1. Boyce BF
  2. Li J
  3. Xing L
  4. Yao Z
  Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption.; Frontiers in immunology; Vol 9. 2018.
• 1. Zhang L
  2. Chang J
  3. Zhao Y
  4. Xu H
  5. Wang T
  6. Li Q
  7. Xing L
  8. Huang J
  9. Wang Y
  10. Liang Q
  Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis.; International journal of nanomedicine; Vol 13. 2018.
• 1. Sun W
  2. Zhang H
  3. Wang H
  4. Chiu YG
  5. Wang M
  6. Ritchlin CT
  7. Kiernan A
  8. Boyce BF
  9. Xing L
  Targeting Notch-Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 32(7). 2017 Jul.
• 1. Lawal RA
  2. Zhou X
  3. Batey K
  4. Hoffman CM
  5. Georger MA
  6. Radtke F
  7. Hilton MJ
  8. Xing L
  9. Frisch BJ
  10. Calvi LM
  The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 32(6). 2017 Jun.
• 1. Xing L
  2. Higuma T
  3. Wang Z
  4. Aguirre AD
  5. Mizuno K
  6. Takano M
  7. Dauerman HL
  8. Park SJ
  9. Jang Y
  10. Kim CJ
  11. Kim SJ
  12. Choi SY
  13. Itoh T
  14. Uemura S
  15. Lowe H
  16. Walters DL
  17. Barlis P
  18. Lee S
  19. Lerman A
  20. Toma C
  21. Tan JWC
  22. Yamamoto E
  23. Bryniarski K
  24. Dai J
  25. Zanchin T
  26. Zhang S
  27. Yu B
  28. Lee H
  29. Fujimoto J
  30. Fuster V
  31. Jang IK
  Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study.; Journal of the American College of Cardiology; Vol 69(20). 2017 May 23.
• 1. Huang QQ
  2. Birkett R
  3. Doyle RE
  4. Haines GK
  5. Perlman H
  6. Shi B
  7. Homan P
  8. Xing L
  9. Pope RM
  Association of Increased F4/80(high) Macrophages With Suppression of Serum-Transfer Arthritis in Mice With Reduced FLIP in Myeloid Cells.; Arthritis & rheumatology (Hoboken, N.J.). 2017 May 16.
• 1. Wang W
  2. Wang H
  3. Zhou X
  4. Li X
  5. Sun W
  6. Dellinger M
  7. Boyce BF
  8. Xing L
  Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 32(5). 2017 May.
• 1. Liu J
  2. Li X
  3. Zhang H
  4. Gu R
  5. Wang Z
  6. Gao Z
  7. Xing L
  Ubiquitin E3 ligase Itch negatively regulates osteoblast function by promoting proteasome degradation of osteogenic proteins.; Bone & joint research; Vol 6(3). 2017 Mar.
• 1. Li X
  2. Sun W
  3. Li J
  4. Wang M
  5. Zhang H
  6. Pei L
  7. Boyce BF
  8. Wang Z
  9. Xing L
  Clomipramine causes osteoporosis by promoting osteoclastogenesis via E3 ligase Itch, which is prevented by Zoledronic acid.; Scientific reports; Vol 7. 2017 Feb 01.
• 1. Bouta EM
  2. Kuzin I
  3. de Mesy Bentley K
  4. Wood RW
  5. Rahimi H
  6. Ji RC
  7. Ritchlin CT
  8. Bottaro A
  9. Xing L
  10. Schwarz EM
  Treatment of Tumor Necrosis Factor-Transgenic Mice With Anti-Tumor Necrosis Factor Restores Lymphatic Contractions, Repairs Lymphatic Vessels, and May Increase Monocyte/Macrophage Egress.; Arthritis & rheumatology (Hoboken, N.J.). 2017 Jan 24.
• 1. Xu H
  2. Bouta EM
  3. Wood RW
  4. Schwarz EM
  5. Wang Y
  6. Xing L
  Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis.; Bone research; Vol 5. 2017.
• 1. Li J
  2. Chen Y
  3. Zhang L
  4. Xing L
  5. Xu H
  6. Wang Y
  7. Shi Q
  8. Liang Q
  Total saponins of panaxnotoginseng promotes lymphangiogenesis by activation VEGF-C expression of lymphatic endothelial cells.; Journal of ethnopharmacology; Vol 193. 2016 Dec 04.
• 1. Huang QQ
  2. Hossain MM
  3. Sun W
  4. Xing L
  5. Pope RM
  6. Jin JP
  Deletion of calponin 2 in macrophages attenuates the severity of inflammatory arthritis in mice.; American journal of physiology. Cell physiology; Vol 311(4). 2016 Oct 01.
• 1. Rahimi H
  2. Bell R
  3. Bouta EM
  4. Wood RW
  5. Xing L
  6. Ritchlin CT
  7. Schwarz EM
  Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential.; Arthritis research & therapy; Vol 18. 2016 Sep 01.
• 1. Zhang H
  2. Sun W
  3. Li X
  4. Wang M
  5. Boyce BF
  6. Hilton MJ
  7. Xing L
  Use of Hes1-GFP reporter mice to assess activity of the Hes1 promoter in bone cells under chronic inflammation.; Bone; Vol 90. 2016 Sep.
• 1. Meednu N
  2. Zhang H
  3. Owen T
  4. Sun W
  5. Wang V
  6. Cistrone C
  7. Rangel-Moreno J
  8. Xing L
  9. Anolik JH
  Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis.; Arthritis & rheumatology (Hoboken, N.J.); Vol 68(4). 2016 Apr.
• 1. Liang Q
  2. Ju Y
  3. Chen Y
  4. Wang W
  5. Li J
  6. Zhang L
  7. Xu H
  8. Wood RW
  9. Schwarz EM
  10. Boyce BF
  11. Wang Y
  12. Xing L
  Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice.; Arthritis research & therapy; Vol 18. 2016 Mar 12.
• 1. Chen Y
  2. Li J
  3. Li Q
  4. Wang T
  5. Xing L
  6. Xu H
  7. Wang Y
  8. Shi Q
  9. Zhou Q
  10. Liang Q
  Du-Huo-Ji-Sheng-Tang Attenuates Inflammation of TNF-Tg Mice Related to Promoting Lymphatic Drainage Function.; Evidence-based complementary and alternative medicine : eCAM; Vol 2016. 2016.
• 1. Liang QQ
  2. Shi Q
  3. Wood RW
  4. Xing LP
  5. Wang YJ
  Peri-articular lymphatic system and "Bi" theory of Chinese medicine in the pathogenesis and treatment of arthritis.; Chinese journal of integrative medicine; Vol 21(9). 2015 Sep.
• 1. Shu L
  2. Beier E
  3. Sheu T
  4. Zhang H
  5. Zuscik MJ
  6. Puzas EJ
  7. Boyce BF
  8. Mooney RA
  9. Xing L
  High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment.; Calcified tissue international; Vol 96(4). 2015 Apr.
• 1. Boyce BF
  2. Xiu Y
  3. Li J
  4. Xing L
  5. Yao Z
  NF-κB-Mediated Regulation of Osteoclastogenesis.; Endocrinology and metabolism (Seoul, Korea); Vol 30(1). 2015 Mar 27.
• 1. Bouta EM
  2. Li J
  3. Ju Y
  4. Brown EB
  5. Ritchlin CT
  6. Xing L
  7. Schwarz EM
  The Role of the Lymphatic System in Inflammatory-Erosive Arthritis.; Seminars in cell & developmental biology. 2015 Jan 15.
• 1. Wang Z
  2. Wang J
  3. Li X
  4. Xing L
  5. Ding Y
  6. Shi P
  7. Zhang Y
  8. Guo S
  9. Shu X
  10. Shan B
  Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2.; International journal of oncology; Vol 45(4). 2014 Oct.
• 1. Cui HB
  2. Ge HE
  3. Bai XY
  4. Zhang W
  5. Zhang YY
  6. Wang J
  7. Li X
  8. Xing LP
  9. Guo SH
  10. Wang ZY
  Effect of neoadjuvant chemotherapy combined with hyperthermic intraperitoneal perfusion chemotherapy on advanced gastric cancer.; Experimental and therapeutic medicine; Vol 7(5). 2014 May.
• 1. Yao Z
  2. Li Y
  3. Yin X
  4. Dong Y
  5. Xing L
  6. Boyce BF
  NF-κB RelB negatively regulates osteoblast differentiation and bone formation.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 29(4). 2014 Apr.
• 1. Juneja SC
  2. Vonica A
  3. Zeiss C
  4. Lezon-Geyda K
  5. Yatsula B
  6. Sell DR
  7. Monnier VM
  8. Lin S
  9. Ardito T
  10. Eyre D
  11. Reynolds D
  12. Yao Z
  13. Awad HA
  14. Yu H
  15. Wilson M
  16. Honnons S
  17. Boyce BF
  18. Xing L
  19. Zhang Y
  20. Perkins AS
  Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.; Bone; Vol 60. 2014 Mar.
• 1. Shi J
  2. Liang Q
  3. Zuscik M
  4. Shen J
  5. Chen D
  6. Xu H
  7. Wang YJ
  8. Chen Y
  9. Wood RW
  10. Li J
  11. Boyce BF
  12. Xing L
  Distribution and alteration of lymphatic vessels in knee joints of normal and osteoarthritic mice.; Arthritis & rheumatology (Hoboken, N.J.); Vol 66(3). 2014 Mar.
• 1. Wang B
  2. Jin H
  3. Zhu M
  4. Li J
  5. Zhao L
  6. Zhang Y
  7. Tang D
  8. Xiao G
  9. Xing L
  10. Boyce BF
  11. Chen D
  Chondrocyte β-catenin signaling regulates postnatal bone remodeling through modulation of osteoclast formation in a murine model.; Arthritis & rheumatology (Hoboken, N.J.); Vol 66(1). 2014 Jan.
• 1. Brown ML
  2. Yukata K
  3. Farnsworth CW
  4. Chen DG
  5. Awad H
  6. Hilton MJ
  7. O'Keefe RJ
  8. Xing L
  9. Mooney RA
  10. Zuscik MJ
  Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus.; PloS one; Vol 9(6). 2014.