URMC / Labs / Zhao Lab / Publications Publications Chen LHayden MSGilmore ESAlexander-Savino COleksyn DGillespie KZhao JPoligone B PKK Deletion in Basal Keratinocytes Promotes Tumorigenesis After Chemical Carcinogenesis.; Carcinogenesis. 2017 Nov 22. Oleksyn DZhao JVosoughi AZhao JCMisra RPentland APRyan DAnolik JRitchlin CLooney JAnandarajah APSchwartz GCalvi LMGeorger MMohan CSanz IChen L PKK deficiency in B cells prevents lupus development in Sle lupus mice.; Immunology letters; Vol 185. 2017 Mar 06. Chen LOleksyn DPulvino MSanz IRyan DRyan CLin CSPoligone BPentland APRitchlin CZhao J A critical role for the protein kinase PKK in the maintenance of recirculating mature B cells and the development of B1 cells.; Immunology letters; Vol 172. 2016 Apr. Pulvino MChen LOleksyn DLi JCompitello GRossi RSpence SBalakrishnan VJordan CPoligone BCasulo CBurack RShapiro JLBernstein SFriedberg JWDeshaies RJLand HZhao J Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline.; Oncotarget; Vol 6(17). 2015 Jun 20. Poligone BGilmore ESAlexander CVOleksyn DGillespie KZhao JIbrahim SFPentland APBrown MDChen L PKK suppresses tumor growth and is decreased in squamous cell carcinoma of the skin.; The Journal of investigative dermatology; Vol 135(3). 2015 Mar. Kim SWSchifano MOleksyn DJordan CTRyan DInsel RZhao JChen L Protein kinase C-associated kinase regulates NF-κB activation through inducing IKK activation.; International journal of oncology; Vol 45(4). 2014 Oct. Oleksyn DPulvino MZhao JMisra RVosoughi AJenks STipton CLund FSchwartz GGoldman BMohan CMehta KMehta MLeitgets MSanz IChen L Protein kinase Cβ is required for lupus development in Sle mice.; Arthritis and rheumatism; Vol 65(4). 2013 Apr. Pulvino MLiang YOleksyn DDeRan MVan Pelt EShapiro JSanz IChen LZhao J Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A.; Blood; Vol 120(8). 2012 Aug 23. Kim SWOleksyn DWRossi RMJordan CTSanz IChen LZhao J Protein kinase C-associated kinase is required for NF-kappaB signaling and survival in diffuse large B-cell lymphoma cells.; Blood; Vol 111(3). 2008 Feb 1. DeRan MPulvino MGreene ESu CZhao J Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition.; Molecular and cellular biology; Vol 28(1). 2008 Jan. Le XFBedrosian IMao WMurray MLu ZKeyomarsi KLee MHZhao JBast RC Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.; Cell cycle (Georgetown, Tex.); Vol 5(15). 2006 Aug. Zhao J Coordination of DNA synthesis and histone gene expression during normal cell cycle progression and after DNA damage.; Cell cycle (Georgetown, Tex.); Vol 3(6). 2004 Jun. Su CGao GSchneider SHelt CWeiss CO'Reilly MABohmann DZhao J DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway.; The EMBO journal; Vol 23(5). 2004 Mar 10. Barbie DAKudlow BAFrock RZhao JJohnson BRDyson NHarlow EKennedy BK Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit.; Molecular and cellular biology; Vol 24(2). 2004 Jan. Gao GBracken APBurkard KPasini DClasson MAttwooll CSagara MImai THelin KZhao J NPAT expression is regulated by E2F and is essential for cell cycle progression.; Molecular and cellular biology; Vol 23(8). 2003 Apr. Zhao JKennedy BKLawrence BDBarbie DAMatera AGFletcher JAHarlow E NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription.; Genes & development; Vol 14(18). 2000 Sep 15. Siwicki JHedberg YNowak RLoden MZhao JLandberg GRoos G Spontaneously immortalized IL-2 dependent T cell lines demonstrate p16 overexpression, normal pRb/p53 and upregulation of cyclins E or D2.; Exp. Gernotol.; Vol 35, pp. 375-388. 2000 Jan 01. Zhao JDynlacht BImai THori THarlow E Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry.; Genes & development; Vol 12(4). 1998 Feb 15. Wang YZhao JClapper JMartin LDDu CDeVore ERHarkins KDobbs DLBenbow RM Mimosine differentially inhibits DNA replication and cell cycle progression in somatic cells compared to embryonic cells of Xenopus laevis.; Experimental cell research; Vol 217(1). 1995 Mar. Zhao JBenbow RM Inhibition of DNA replication in cell-free extracts of Xenopus laevis eggs by extracts of Xenopus laevis oocytes.; Developmental biology; Vol 164(1). 1994 Jul. Zhao JBenbow RM An inhibitor of DNA topoisomerase I from Xenopus laevis ovaries.; Biochemistry; Vol 32(40). 1993 Oct 12. Benbow RMZhao JLarson DD On the nature of origins of DNA replication in eukaryotes.; BioEssays : news and reviews in molecular, cellular and developmental biology; Vol 14(10). 1992 Oct. Zhao JYFord CFGlatz CERougvie MAGendel SM Polyelectrolyte precipitation of beta-galactosidase fusions containing poly-aspartic acid tails.; Journal of biotechnology; Vol 14(3-4). 1990 Jun. Benbow RMPoll EHZhao JMarini NJStowers DJ DNA unwinding and strand synthesis during replication in Xenopus laevis embryos.; Papis, T.S. (ed) Gene Regulation and AIDS: Transcriptional Activation, Retroviruses, and Pathogenesis. Portfolio Publishing Company, Houston.. 1990 Jan 01. Wu YZhang SMa GSong DZhao J Biosynthesis of indigo involving transferring naphthalene-degrading plasmid DNA from Pseudomonas to E. coli. 16,; Acta Genetics Sinica; Vol 16, pp. 318-324. 1989 Jan 01. Zhang SZhao JChen YWang Z Degradation of phenanthrene by Pseudomonas sp. P12.; Acta Environmental Science Sinica; Vol 9, pp. 80-85. 1989 Jan 01. Zhu XMZhao JYLuo QXWang ZT [Analysis of degradative plasmids by pyrolysis gas liquid chromatography].; Wei sheng wu xue bao = Acta microbiologica Sinica; Vol 28(1). 1988 Mar. Zhao JWang ZJian H Isolation of a naphthalene-degrading plasmid and its in situ transfer among bacteria in a waste water treatment plant.; Acta Environmental Science Sinica; Vol 8, pp. 84-92. 1988 Jan 01.