Publications

• 1. Morais P
  2. Zhang R
  3. Yu YT
  Therapeutic Nonsense Suppression Modalities: From Small Molecules to Nucleic Acid-Based Approaches.; Biomedicines; Vol 12(6). 2024 Jun 10.
• 1. Pan Y
  2. Adachi H
  3. He X
  4. Chen JL
  5. Yu YT
  6. Boutz PL
  Updated Pseudo-seq Protocol for Transcriptome-Wide Detection of Pseudouridines.; Bio-protocol; Vol 14(9), pp. e4985. 2024 May 05.
• 1. Chen JL
  2. Leeder WM
  3. Morais P
  4. Adachi H
  5. Yu YT
  Pseudouridylation-mediated gene expression modulation.; The Biochemical journal; Vol 481(1), pp. 1-16. 2024 Jan 10.
• 1. Adachi H
  2. Pan Y
  3. He X
  4. Chen JL
  5. Klein B
  6. Platenburg G
  7. Morais P
  8. Boutz P
  9. Yu YT
  Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes.; Molecular cell. 2023 Feb 03.
• 1. Adachi H
  2. Chen JL
  3. Yin Q
  4. Morais P
  5. Yu YT
  In Vitro Reconstitution of Pseudouridylation Catalyzed by Human Box H/ACA Ribonucleoprotein Particles.; Methods in molecular biology (Clifton, N.J.); Vol 2666, pp. 177-191. 2023.
• 1. Adachi H
  2. Hengesbach M
  3. Yu YT
  4. Morais P
  From Antisense RNA to RNA Modification: Therapeutic Potential of RNA-Based Technologies.; Biomedicines; Vol 9(5). 2021 May 14.
• 1. Morais P
  2. Adachi H
  3. Yu YT
  Spliceosomal snRNA Epitranscriptomics.; Frontiers in genetics; Vol 12. 2021.
• 1. Morais P
  2. Adachi H
  3. Yu YT
  The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines.; Frontiers in cell and developmental biology; Vol 9. 2021.
• 1. Morais P
  2. Adachi H
  3. Yu YT
  Suppression of Nonsense Mutations by New Emerging Technologies.; International journal of molecular sciences; Vol 21(12). 2020 Jun 20.
• 1. Adachi H
  2. Yu YT
  Pseudouridine-mediated stop codon read-through in S. cerevisiae is sequence context-independent.; RNA (New York, N.Y.). 2020 May 20.
• 1. Adachi H
  2. DeZoysa MD
  3. Yu YT
  Detection and Quantification of Pseudouridine in RNA.; Methods in molecular biology (Clifton, N.J.); Vol 1870. 2019.
• 1. Adachi H
  2. De Zoysa MD
  3. Yu YT
  Post-transcriptional pseudouridylation in mRNA as well as in some major types of noncoding RNAs.; Biochimica et biophysica acta. Gene regulatory mechanisms. 2018 Nov 08.
• 1. De Zoysa MD
  2. Wu G
  3. Katz R
  4. Yu YT
  Guide-substrate base-pairing requirement for box H/ACA RNA-guided RNA pseudouridylation.; RNA (New York, N.Y.). 2018 Jun 05.
• 1. Zhao Y
  2. Dunker W
  3. Yu YT
  4. Karijolich J
  The Role of Noncoding RNA Pseudouridylation in Nuclear Gene Expression Events.; Frontiers in bioengineering and biotechnology; Vol 6. 2018.
• 1. Ge J
  2. Karijolich J
  3. Zhai Y
  4. Zheng J
  5. Yu YT
  5-Fluorouracil Treatment Alters the Efficiency of Translational Recoding.; Genes; Vol 8(11). 2017 Oct 31.
• 1. Poole AR
  2. Vicino I
  3. Adachi H
  4. Yu YT
  5. Hebert MD
  Regulatory RNPs: a novel class of ribonucleoproteins that potentially contribute to ribosome heterogeneity.; Biology open. 2017 Aug 14.
• 1. De Zoysa MD
  2. Yu YT
  Posttranscriptional RNA Pseudouridylation.; The Enzymes; Vol 41. 2017.
• 1. Xu C
  2. Ishikawa H
  3. Izumikawa K
  4. Li L
  5. He H
  6. Nobe Y
  7. Yamauchi Y
  8. Shahjee HM
  9. Wu XH
  10. Yu YT
  11. Isobe T
  12. Takahashi N
  13. Min J
  Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.; Genes & development; Vol 30(21). 2016 Nov 01.
• 1. Wu G
  2. Radwan MK
  3. Xiao M
  4. Adachi H
  5. Fan J
  6. Yu YT
  The TOR signaling pathway regulates starvation-induced pseudouridylation of yeast U2 snRNA.; RNA (New York, N.Y.). 2016 Jun 7.
• 1. Wu G
  2. Adachi H
  3. Ge J
  4. Stephenson D
  5. Query CC
  6. Yu YT
  Pseudouridines in U2 snRNA stimulate the ATPase activity of Prp5 during spliceosome assembly.; The EMBO journal; Vol 35(6). 2016 Mar 15.
• 1. Huang C
  2. Karijolich J
  3. Yu YT
  Detection and quantification of RNA 2'-O-methylation and pseudouridylation.; Methods (San Diego, Calif.). 2016 Feb 4.
• 1. Huang C
  2. Wu G
  3. Yu YT
  Purification and Functional Reconstitution of Box H/ACA Ribonucleoprotein Particles.; Methods in molecular biology (Clifton, N.J.); Vol 1421. 2016.
• 1. Karijolich J
  2. Yi C
  3. Yu YT
  Transcriptome-wide dynamics of RNA pseudouridylation.; Nature reviews. Molecular cell biology; Vol 16(10). 2015 Oct.
• 1. Karijolich J
  2. Yu YT
  The new era of RNA modification.; RNA (New York, N.Y.); Vol 21(4). 2015 Apr.
• 1. Wu G
  2. Huang C
  3. Yu YT
  Pseudouridine in mRNA: Incorporation, Detection, and Recoding.; Methods in enzymology; Vol 560. 2015.
• 1. Enwerem II
  2. Wu G
  3. Yu YT
  4. Hebert MD
  Cajal body proteins differentially affect the processing of box C/D scaRNPs.; PloS one; Vol 10(4). 2015.
• 1. Adachi H
  2. Yu YT
  Insight into the mechanisms and functions of spliceosomal snRNA pseudouridylation.; World journal of biological chemistry; Vol 5(4). 2014 Nov 26.
• 1. Karijolich J
  2. Yu YT
  Therapeutic suppression of premature termination codons: mechanisms and clinical considerations (review).; International journal of molecular medicine; Vol 34(2). 2014 Aug.
• 1. Lim SJ
  2. Scott A
  3. Xiong XP
  4. Vahidpour S
  5. Karijolich J
  6. Guo D
  7. Pei S
  8. Yu YT
  9. Zhou R
  10. Li WX
  Requirement for CRIF1 in RNA interference and Dicer-2 stability.; RNA biology; Vol 11(9). 2014.
• 1. Yu YT
  2. Meier UT
  RNA-guided isomerization of uridine to pseudouridine--pseudouridylation.; RNA biology; Vol 11(12). 2014.
• 1. Adachi H
  2. Yu YT
  Purification of radiolabeled RNA products using denaturing gel electrophoresis.; Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]; Vol 105. 2014.
• 1. Fernández IS
  2. Ng CL
  3. Kelley AC
  4. Wu G
  5. Yu YT
  6. Ramakrishnan V
  Unusual base pairing during the decoding of a stop codon by the ribosome.; Nature; Vol 500(7460). 2013 Aug 01.
• 1. Ge J
  2. Yu YT
  RNA pseudouridylation: new insights into an old modification.; Trends in biochemical sciences; Vol 38(4). 2013 Apr.
• 1. Huang C
  2. Yu YT
  Synthesis and labeling of RNA in vitro.; Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]; Vol Chapter 4. 2013 Apr.
• 1. Huang C
  2. Yu YT
  Synthesis and labeling of RNA in vitro.; Wiley Current Protocols in Molecular Biology. 2013 Jan 01.
• 1. Huang C
  2. Wu G
  3. Yu YT
  Inducing nonsense suppression by targeted pseudouridylation.; Nature protocols; Vol 7(4). 2012 Mar 29.
• 1. Huang C
  2. Wu G
  3. Yu YT
  Inducing nonsense suppression by targeted pseudouridylation.; Nature Protocols; Vol 7, pp. 789-800. 2012 Jan 01.
• 1. Yu AT
  2. Ge J
  3. Yu YT
  Pseudouridines in spliceosomal snRNAs.; Protein & cell; Vol 2(9). 2011 Sep.
• 1. Wu G
  2. Yu AT
  3. Kantartzis A
  4. Yu YT
  Functions and mechanisms of spliceosomal small nuclear RNA pseudouridylation.; Wiley interdisciplinary reviews. RNA; Vol 2(4). 2011 Jul.
• 1. Karijolich J
  2. Yu YT
  Converting nonsense codons into sense codons by targeted pseudouridylation.; Nature; Vol 474(7351). 2011 Jun 16.
• 1. Wu G
  2. Xiao M
  3. Yang C
  4. Yu YT
  U2 snRNA is inducibly pseudouridylated at novel sites by Pus7p and snR81 RNP.; The EMBO journal; Vol 30(1). 2011 Jan 05.
• 1. Huang C
  2. Karijolich J
  3. Yu YT
  Post-transcriptional modification of RNAs by artificial Box H/ACA and Box C/D RNPs.; Methods in molecular biology (Clifton, N.J.); Vol 718. 2011.
• 1. Wu G
  2. Yu AT
  3. Kantartzis A
  4. Yu YT
  Functions and Mechanisms of Spliceosomal snRNA pseudouridylation.; Wiley Interdisciplinary Reviews (WIREs) RNA; Vol 2, pp. 571-581. 2011 Jan 01.
• 1. Yu AT
  2. Ge J
  3. Yu YT
  Pseudouridines in spliceosomal snRNAs.; Protein & Cell; Vol 2, pp. 712-725. 2011 Jan 01.
• 1. Huang C
  2. Yu YT
  Targeted 2'-O methylation at a nucleotide within the pseudoknot of telomerase RNA reduces telomerase activity in vivo.; Molecular and cellular biology; Vol 30(18). 2010 Sep.
• 1. Chen C
  2. Zhao X
  3. Kierzek R
  4. Yu YT
  A flexible RNA backbone within the polypyrimidine tract is required for U2AF65 binding and pre-mRNA splicing in vivo.; Molecular and cellular biology; Vol 30(17). 2010 Sep.
• 1. Ge J
  2. Liu H
  3. Yu YT
  Regulation of pre-mRNA splicing in Xenopus oocytes by targeted 2'-O-methylation.; RNA (New York, N.Y.); Vol 16(5). 2010 May.
• 1. Karijolich J
  2. Yu YT
  Spliceosomal snRNA modifications and their function.; RNA biology; Vol 7(2). 2010 Mar.
• 1. Karijolich J
  2. Kantartzis A
  3. Yu YT
  RNA modifications: a mechanism that modulates gene expression.; Methods in molecular biology (Clifton, N.J.); Vol 629. 2010.
• 1. Karijolich J
  2. Kantartzis A
  3. Yu YT
  Quantitative analysis of RNA modifications.; Methods in molecular biology (Clifton, N.J.); Vol 629. 2010.