Publications

• 1. Martin AT
  2. Giri S
  3. Safronova A
  4. Eliseeva SI
  5. Kwok SF
  6. Yarovinsky F
  Parasite-induced IFN-γ regulates host defense via CD115 and mTOR-dependent mechanism of tissue-resident macrophage death.; PLoS pathogens; Vol 20(2), pp. e1011502. 2024 Feb 20.
• 1. Araujo A
  2. Safronova A
  3. Burger E
  4. López-Yglesias A
  5. Giri S
  6. Camanzo ET
  7. Martin AT
  8. Grivennikov S
  9. Yarovinsky F
  IFN-γ mediates Paneth cell death via suppression of mTOR.; eLife; Vol 10. 2021 Oct 11.
• 1. López-Yglesias AH
  2. Burger E
  3. Camanzo E
  4. Martin AT
  5. Araujo AM
  6. Kwok SF
  7. Yarovinsky F
  T-bet-dependent ILC1- and NK cell-derived IFN-γ mediates cDC1-dependent host resistance against Toxoplasma gondii.; PLoS pathogens; Vol 17(1). 2021 Jan 19.
• 1. Coombs RS
  2. Blank ML
  3. English ED
  4. Adomako-Ankomah Y
  5. Urama IS
  6. Martin AT
  7. Yarovinsky F
  8. Boyle JP
  Immediate interferon gamma induction determines murine host compatibility differences between Toxoplasma gondii and Neospora caninum.; Infection and immunity. 2020 Feb 03.
• 1. López-Yglesias AH
  2. Camanzo E
  3. Martin AT
  4. Araujo AM
  5. Yarovinsky F
  TLR11-independent inflammasome activation is critical for CD4+ T cell-derived IFN-γ production and host resistance to Toxoplasma gondii.; PLoS pathogens; Vol 15(6). 2019 Jun 13.
• 1. Safronova A
  2. Araujo A
  3. Camanzo ET
  4. Moon TJ
  5. Elliott MR
  6. Beiting DP
  7. Yarovinsky F
  Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii.; Nature immunology. 2018 Nov 19.
• 1. Burger E
  2. Araujo A
  3. López-Yglesias A
  4. Rajala MW
  5. Geng L
  6. Levine B
  7. Hooper LV
  8. Burstein E
  9. Yarovinsky F
  Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation.; Cell host & microbe; Vol 23(2). 2018 Feb 14.
• 1. López-Yglesias AH
  2. Burger E
  3. Araujo A
  4. Martin AT
  5. Yarovinsky F
  T-bet-independent Th1 response induces intestinal immunopathology during Toxoplasma gondii infection.; Mucosal immunology. 2018 Jan 03.
• 1. Burger E
  2. Araujo A
  3. López-Yglesias A
  4. Rajala MW
  5. Geng L
  6. Levine B
  7. Hooper LV
  8. Burstein E
  9. Yarovinsky F
  Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation; Cell Host & Microbe. 2018 Jan 01.
• 1. Song J
  2. Wilhelm CL
  3. Wangdi T
  4. Maira-Litran T
  5. Lee SJ
  6. Raetz M
  7. Sturge CR
  8. Mirpuri J
  9. Pei J
  10. Grishin NV
  11. McSorley SJ
  12. Gewirtz AT
  13. Bäumler AJ
  14. Pier GB
  15. Galán JE
  16. Yarovinsky F
  Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi.; Cell; Vol 164(5). 2016 Feb 25.
• 1. Sturge CR
  2. Burger E
  3. Raetz M
  4. Hooper LV
  5. Yarovinsky F
  Cutting Edge: Developmental Regulation of IFN-γ Production by Mouse Neutrophil Precursor Cells.; Journal of immunology (Baltimore, Md. : 1950); Vol 195(1). 2015 Jul 01.
• 1. Oh JZ
  2. Ravindran R
  3. Chassaing B
  4. Carvalho FA
  5. Maddur MS
  6. Bower M
  7. Hakimpour P
  8. Gill KP
  9. Nakaya HI
  10. Yarovinsky F
  11. Sartor RB
  12. Gewirtz AT
  13. Pulendran B
  TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination.; Immunity; Vol 41(3). 2014 Sep 18.
• 1. Wilhelm CL
  2. Yarovinsky F
  Apicomplexan infections in the gut.; Parasite immunology; Vol 36(9). 2014 Sep.
• 1. Sturge CR
  2. Yarovinsky F
  Complex immune cell interplay in the gamma interferon response during Toxoplasma gondii infection.; Infection and immunity; Vol 82(8). 2014 Aug.
• 1. Li H
  2. Chan L
  3. Bartuzi P
  4. Melton SD
  5. Weber A
  6. Ben-Shlomo S
  7. Varol C
  8. Raetz M
  9. Mao X
  10. Starokadomskyy P
  11. van Sommeren S
  12. Mokadem M
  13. Schneider H
  14. Weisberg R
  15. Westra HJ
  16. Esko T
  17. Metspalu A
  18. Kumar V
  19. Faubion WA
  20. Yarovinsky F
  21. Hofker M
  22. Wijmenga C
  23. Kracht M
  24. Franke L
  25. Aguirre V
  26. Weersma RK
  27. Gluck N
  28. van de Sluis B
  29. Burstein E
  Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.; Gastroenterology; Vol 147(1). 2014 Jul.
• 1. Yarovinsky F
  Innate immunity to Toxoplasma gondii infection.; Nature reviews. Immunology; Vol 14(2). 2014 Feb.
• 1. Mirpuri J
  2. Raetz M
  3. Sturge CR
  4. Wilhelm CL
  5. Benson A
  6. Savani RC
  7. Hooper LV
  8. Yarovinsky F
  Proteobacteria-specific IgA regulates maturation of the intestinal microbiota.; Gut microbes; Vol 5(1). 2014 Jan.
• 1. Raetz M
  2. Kibardin A
  3. Sturge CR
  4. Pifer R
  5. Li H
  6. Burstein E
  7. Ozato K
  8. Larin S
  9. Yarovinsky F
  Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin.; Journal of immunology (Baltimore, Md. : 1950); Vol 191(9). 2013 Nov 01.
• 1. Sturge CR
  2. Benson A
  3. Raetz M
  4. Wilhelm CL
  5. Mirpuri J
  6. Vitetta ES
  7. Yarovinsky F
  TLR-independent neutrophil-derived IFN-γ is important for host resistance to intracellular pathogens.; Proceedings of the National Academy of Sciences of the United States of America; Vol 110(26). 2013 Jun 25.
• 1. Raetz M
  2. Hwang SH
  3. Wilhelm CL
  4. Kirkland D
  5. Benson A
  6. Sturge CR
  7. Mirpuri J
  8. Vaishnava S
  9. Hou B
  10. Defranco AL
  11. Gilpin CJ
  12. Hooper LV
  13. Yarovinsky F
  Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells.; Nature immunology; Vol 14(2). 2013 Feb.
• 1. Hwang SH
  2. Lee H
  3. Yamamoto M
  4. Jones LA
  5. Dayalan J
  6. Hopkins R
  7. Zhou XJ
  8. Yarovinsky F
  9. Connolly JE
  10. Curotto de Lafaille MA
  11. Wakeland EK
  12. Fairhurst AM
  B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice.; Journal of immunology (Baltimore, Md. : 1950); Vol 189(12). 2012 Dec 15.
• 1. Grivennikov SI
  2. Wang K
  3. Mucida D
  4. Stewart CA
  5. Schnabl B
  6. Jauch D
  7. Taniguchi K
  8. Yu GY
  9. Osterreicher CH
  10. Hung KE
  11. Datz C
  12. Feng Y
  13. Fearon ER
  14. Oukka M
  15. Tessarollo L
  16. Coppola V
  17. Yarovinsky F
  18. Cheroutre H
  19. Eckmann L
  20. Trinchieri G
  21. Karin M
  Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.; Nature; Vol 491(7423). 2012 Nov 08.
• 1. Kirkland D
  2. Benson A
  3. Mirpuri J
  4. Pifer R
  5. Hou B
  6. DeFranco AL
  7. Yarovinsky F
  B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage.; Immunity; Vol 36(2). 2012 Feb 24.
• 1. Benson A
  2. Murray S
  3. Divakar P
  4. Burnaevskiy N
  5. Pifer R
  6. Forman J
  7. Yarovinsky F
  Microbial infection-induced expansion of effector T cells overcomes the suppressive effects of regulatory T cells via an IL-2 deprivation mechanism.; Journal of immunology (Baltimore, Md. : 1950); Vol 188(2). 2012 Jan 15.
• 1. Mirpuri J
  2. Yarovinsky F
  IL-6 signaling SOCS critical for IL-12 host response to Toxoplasma gondii.; Future microbiology; Vol 7(1). 2012 Jan.
• 1. Mirpuri J
  2. Sotnikov I
  3. Myers L
  4. Denning TL
  5. Yarovinsky F
  6. Parkos CA
  7. Denning PW
  8. Louis NA
  Lactobacillus rhamnosus (LGG) regulates IL-10 signaling in the developing murine colon through upregulation of the IL-10R2 receptor subunit.; PloS one; Vol 7(12). 2012.
• 1. Broadhurst MJ
  2. Ardeshir A
  3. Kanwar B
  4. Mirpuri J
  5. Gundra UM
  6. Leung JM
  7. Wiens KE
  8. Vujkovic-Cvijin I
  9. Kim CC
  10. Yarovinsky F
  11. Lerche NW
  12. McCune JM
  13. Loke P
  Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.; PLoS pathogens; Vol 8(11). 2012.
• 1. McFadden N
  2. Bailey D
  3. Carrara G
  4. Benson A
  5. Chaudhry Y
  6. Shortland A
  7. Heeney J
  8. Yarovinsky F
  9. Simmonds P
  10. Macdonald A
  11. Goodfellow I
  Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4.; PLoS pathogens; Vol 7(12). 2011 Dec.
• 1. Butcher BA
  2. Fox BA
  3. Rommereim LM
  4. Kim SG
  5. Maurer KJ
  6. Yarovinsky F
  7. Herbert DR
  8. Bzik DJ
  9. Denkers EY
  Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.; PLoS pathogens; Vol 7(9). 2011 Sep.
• 1. Pifer R
  2. Yarovinsky F
  Innate responses to Toxoplasma gondii in mice and humans.; Trends in parasitology; Vol 27(9). 2011 Sep.
• 1. Ismail AS
  2. Severson KM
  3. Vaishnava S
  4. Behrendt CL
  5. Yu X
  6. Benjamin JL
  7. Ruhn KA
  8. Hou B
  9. DeFranco AL
  10. Yarovinsky F
  11. Hooper LV
  Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface.; Proceedings of the National Academy of Sciences of the United States of America; Vol 108(21). 2011 May 24.
• 1. Pifer R
  2. Benson A
  3. Sturge CR
  4. Yarovinsky F
  UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii.; The Journal of biological chemistry; Vol 286(5). 2011 Feb 04.
• 1. Hou B
  2. Benson A
  3. Kuzmich L
  4. DeFranco AL
  5. Yarovinsky F
  Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors.; Proceedings of the National Academy of Sciences of the United States of America; Vol 108(1). 2011 Jan 04.
• 1. Becker AM
  2. Blevins JS
  3. Tomson FL
  4. Eitson JL
  5. Medeiros JJ
  6. Yarovinsky F
  7. Norgard MV
  8. van Oers NS
  Invariant NKT cell development requires a full complement of functional CD3 zeta immunoreceptor tyrosine-based activation motifs.; Journal of immunology (Baltimore, Md. : 1950); Vol 184(12). 2010 Jun 15.
• 1. Wilson MS
  2. Feng CG
  3. Barber DL
  4. Yarovinsky F
  5. Cheever AW
  6. Sher A
  7. Grigg M
  8. Collins M
  9. Fouser L
  10. Wynn TA
  Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections.; Journal of immunology (Baltimore, Md. : 1950); Vol 184(8). 2010 Apr 15.
• 1. Bailey D
  2. Karakasiliotis I
  3. Vashist S
  4. Chung LM
  5. Rees J
  6. Reese J
  7. McFadden N
  8. Benson A
  9. Yarovinsky F
  10. Simmonds P
  11. Goodfellow I
  Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence.; Journal of virology; Vol 84(6). 2010 Mar.
• 1. Sassi A
  2. Brichacek B
  3. Hieny S
  4. Yarovinsky F
  5. Golding H
  6. Grivel JC
  7. Sher A
  8. Margolis L
  Toxoplasma gondii inhibits R5 HIV-1 replication in human lymphoid tissues ex vivo.; Microbes and infection; Vol 11(14-15). 2009 Dec.
• 1. Benson A
  2. Pifer R
  3. Behrendt CL
  4. Hooper LV
  5. Yarovinsky F
  Gut commensal bacteria direct a protective immune response against Toxoplasma gondii.; Cell host & microbe; Vol 6(2). 2009 Aug 20.
• 1. Sanders CJ
  2. Franchi L
  3. Yarovinsky F
  4. Uematsu S
  5. Akira S
  6. Núñez G
  7. Gewirtz AT
  Induction of adaptive immunity by flagellin does not require robust activation of innate immunity.; European journal of immunology; Vol 39(2). 2009 Feb.
• 1. Yarovinsky F
  2. Hieny S
  3. Sher A
  Recognition of Toxoplasma gondii by TLR11 prevents parasite-induced immunopathology.; Journal of immunology (Baltimore, Md. : 1950); Vol 181(12). 2008 Dec 15.
• 1. Yarovinsky F
  Toll-like receptors and their role in host resistance to Toxoplasma gondii.; Immunology letters; Vol 119(1-2). 2008 Aug 15.
• 1. Pepper M
  2. Dzierszinski F
  3. Wilson E
  4. Tait E
  5. Fang Q
  6. Yarovinsky F
  7. Laufer TM
  8. Roos D
  9. Hunter CA
  Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines.; Journal of immunology (Baltimore, Md. : 1950); Vol 180(9). 2008 May 01.
• 1. Plattner F
  2. Yarovinsky F
  3. Romero S
  4. Didry D
  5. Carlier MF
  6. Sher A
  7. Soldati-Favre D
  Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response.; Cell host & microbe; Vol 3(2). 2008 Feb 14.
• 1. Yarovinsky F
  2. Kanzler H
  3. Hieny S
  4. Coffman RL
  5. Sher A
  Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response.; Immunity; Vol 25(4). 2006 Oct.
• 1. Yarovinsky F
  2. Sher A
  Toll-like receptor recognition of Toxoplasma gondii.; International journal for parasitology; Vol 36(3). 2006 Mar.
• 1. Golding H
  2. Khurana S
  3. Yarovinsky F
  4. King LR
  5. Abdoulaeva G
  6. Antonsson L
  7. Owman C
  8. Platt EJ
  9. Kabat D
  10. Andersen JF
  11. Sher A
  CCR5 N-terminal region plays a critical role in HIV-1 inhibition by Toxoplasma gondii-derived cyclophilin-18.; The Journal of biological chemistry; Vol 280(33). 2005 Aug 19.
• 1. Yarovinsky F
  2. Zhang D
  3. Andersen JF
  4. Bannenberg GL
  5. Serhan CN
  6. Hayden MS
  7. Hieny S
  8. Sutterwala FS
  9. Flavell RA
  10. Ghosh S
  11. Sher A
  TLR11 activation of dendritic cells by a protozoan profilin-like protein.; Science (New York, N.Y.); Vol 308(5728). 2005 Jun 10.
• 1. Kurosaka K
  2. Chen Q
  3. Yarovinsky F
  4. Oppenheim JJ
  5. Yang D
  Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.; Journal of immunology (Baltimore, Md. : 1950); Vol 174(10). 2005 May 15.
• 1. Yarovinsky F
  2. Andersen JF
  3. King LR
  4. Caspar P
  5. Aliberti J
  6. Golding H
  7. Sher A
  Structural determinants of the anti-HIV activity of a CCR5 antagonist derived from Toxoplasma gondii.; The Journal of biological chemistry; Vol 279(51). 2004 Dec 17.
• 1. Abe K
  2. Yarovinsky FO
  3. Murakami T
  4. Shakhov AN
  5. Tumanov AV
  6. Ito D
  7. Drutskaya LN
  8. Pfeffer K
  9. Kuprash DV
  10. Komschlies KL
  11. Nedospasov SA
  Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo.; Blood; Vol 101(4). 2003 Feb 15.