Publications

• 1. Jing X
  2. Kotelsky A
  3. Zhang Y
  4. Dirksen R
  5. Mannava S
  6. Buckley M
  7. Lee W
  Mechano-adaptation: Exercise-driven Piezo1 & Piezo2 augmentation and chondroprotection in articular cartilage.; bioRxiv : the preprint server for biology. 2024 Aug 06.
• 1. Anderson DE
  2. Broun KG
  3. Kundu P
  4. Jing X
  5. Tang X
  6. Lu C
  7. Kotelsky A
  8. Mannava S
  9. Lee W
  PIEZO1 is downregulated in glenohumeral chondrocytes in early cuff tear arthropathy following a massive rotator cuff tear in a mouse model.; Frontiers in bioengineering and biotechnology; Vol 11, pp. 1244975. 2023 Sep 05.
• 1. Wise BC
  2. Mora KE
  3. Lee W
  4. Buckley MR
  Murine Hind Limb Explant Model for Studying the Mechanobiology of Achilles Tendon Impingement.; Journal of visualized experiments : JoVE. 2023 Jan 08.
• 1. Fraser D
  2. Nguyen T
  3. Kotelsky A
  4. Lee W
  5. Buckley M
  6. Benoit DSW
  Hydrogel Swelling-Mediated Strain Induces Cell Alignment at Dentin Interfaces.; ACS biomaterials science & engineering. 2022 Jul 06.
• 1. Gao W
  2. Hasan H
  3. Anderson DE
  4. Lee W
  The Role of Mechanically-Activated Ion Channels Piezo1, Piezo2, and TRPV4 in Chondrocyte Mechanotransduction and Mechano-Therapeutics for Osteoarthritis.; Frontiers in cell and developmental biology; Vol 10. 2022.
• 1. Lee W
  2. Nims RJ
  3. Savadipour A
  4. Zhang Q
  5. Leddy HA
  6. Liu F
  7. McNulty AL
  8. Chen Y
  9. Guilak F
  10. Liedtke WB
  Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis.; Proceedings of the National Academy of Sciences of the United States of America; Vol 118(13). 2021 Mar 30.
• 1. Kotelsky A
  2. Elahi A
  3. Nejat Yigit C
  4. Proctor A
  5. Mannava S
  6. Pröschel C
  7. Lee W
  Effect of knee joint loading on chondrocyte mechano-vulnerability and severity of post-traumatic osteoarthritis induced by ACL-injury in mice.; Osteoarthritis and cartilage open; Vol 4(1), pp. 100227. 2021 Jan 15.
• 1. Kanju P
  2. Chen Y
  3. Lee W
  4. Yeo M
  5. Lee SH
  6. Romac J
  7. Shahid R
  8. Fan P
  9. Gooden DM
  10. Simon SA
  11. Spasojevic I
  12. Mook RA
  13. Liddle RA
  14. Guilak F
  15. Liedtke WB
  Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.; Scientific reports; Vol 6. 2016 Jun 01.
• 1. Chen Y
  2. Kanju P
  3. Fang Q
  4. Lee SH
  5. Parekh PK
  6. Lee W
  7. Moore C
  8. Brenner D
  9. Gereau RW
  10. Wang F
  11. Liedtke W
  TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor.; Pain; Vol 155(12). 2014 Dec.
• 1. Lee W
  2. Leddy HA
  3. Chen Y
  4. Lee SH
  5. Zelenski NA
  6. McNulty AL
  7. Wu J
  8. Beicker KN
  9. Coles J
  10. Zauscher S
  11. Grandl J
  12. Sachs F
  13. Guilak F
  14. Liedtke WB
  Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage.; Proceedings of the National Academy of Sciences of the United States of America; Vol 111(47). 2014 Nov 25.
• 1. Lee W
  2. Strümpfer J
  3. Bennett V
  4. Schulten K
  5. Marszalek PE
  Mutation of conserved histidines alters tertiary structure and nanomechanics of consensus ankyrin repeats.; The Journal of biological chemistry; Vol 287(23). 2012 Jun 01.
• 1. Lee W
  2. Zeng X
  3. Rotolo K
  4. Yang M
  5. Schofield CJ
  6. Bennett V
  7. Yang W
  8. Marszalek PE
  Mechanical anisotropy of ankyrin repeats.; Biophysical journal; Vol 102(5). 2012 Mar 07.
• 1. Lee W
  2. Zeng X
  3. Zhou HX
  4. Bennett V
  5. Yang W
  6. Marszalek PE
  Full reconstruction of a vectorial protein folding pathway by atomic force microscopy and molecular dynamics simulations.; The Journal of biological chemistry; Vol 285(49). 2010 Dec 03.
• 1. Kim M
  2. Abdi K
  3. Lee G
  4. Rabbi M
  5. Lee W
  6. Yang M
  7. Schofield CJ
  8. Bennett V
  9. Marszalek PE
  Fast and forceful refolding of stretched alpha-helical solenoid proteins.; Biophysical journal; Vol 98(12). 2010 Jun 16.
• 1. Serquera D
  2. Lee W
  3. Settanni G
  4. Marszalek PE
  5. Paci E
  6. Itzhaki LS
  Mechanical unfolding of an ankyrin repeat protein.; Biophysical journal; Vol 98(7). 2010 Apr 07.
• 1. Jiang Y
  2. Rabbi M
  3. Kim M
  4. Ke C
  5. Lee W
  6. Clark RL
  7. Mieczkowski PA
  8. Marszalek PE
  UVA generates pyrimidine dimers in DNA directly.; Biophysical journal; Vol 96(3). 2009 Feb.
• 1. Rivera M
  2. Lee W
  3. Ke C
  4. Marszalek PE
  5. Cole DG
  6. Clark RL
  Minimizing pulling geometry errors in atomic force microscope single molecule force spectroscopy.; Biophysical journal; Vol 95(8). 2008 Oct.