Publications

• 1. Scott-Hewitt NJ
  2. Folts CJ
  3. Noble MD
  Heterozygous carriers of galactocerebrosidase mutations that cause Krabbe disease have impaired microglial function and defective repair of myelin damage.; Neural regeneration research; Vol 13(3). 2018 Mar.
• 1. Scott-Hewitt NJ
  2. Folts CJ
  3. Hogestyn JM
  4. Piester G
  5. Mayer-Pröschel M
  6. Noble MD
  Heterozygote galactocerebrosidase (GALC) mutants have reduced remyelination and impaired myelin debris clearance following demyelinating injury.; Human molecular genetics. 2017 May 31.
• 1. Folts CJ
  2. Scott-Hewitt N
  3. Pröschel C
  4. Mayer-Pröschel M
  5. Noble M
  Lysosomal Re-acidification Prevents Lysosphingolipid-Induced Lysosomal Impairment and Cellular Toxicity.; PLoS biology; Vol 14(12). 2016 Dec.
• 1. Geary MB
  2. Li H
  3. Zingman A
  4. Ketz J
  5. Zuscik M
  6. De Mesy Bentley KL
  7. Noble M
  8. Elfar JC
  Erythropoietin accelerates functional recovery after moderate sciatic nerve crush injury.; Muscle & nerve. 2016 Nov 07.
• 1. Sundem L
  2. Chris Tseng KC
  3. Li H
  4. Ketz J
  5. Noble M
  6. Elfar J
  Erythropoietin Enhanced Recovery After Traumatic Nerve Injury: Myelination and Localized Effects.; The Journal of hand surgery. 2016 Sep 1.
• 1. Tseng KC
  2. Li H
  3. Clark A
  4. Sundem L
  5. Zuscik M
  6. Noble M
  7. Elfar J
  4-Aminopyridine promotes functional recovery and remyelination in acute peripheral nerve injury.; EMBO molecular medicine; Vol 8(12). 2016 Jan.
• 1. Campbell A
  2. Bushman J
  3. Munger J
  4. Noble M
  5. Pröschel C
  6. Mayer-Pröschel M
  Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia.; Glia. 2015 Oct 15.
• 1. Campbell A
  2. Krupp B
  3. Bushman J
  4. Noble M
  5. Pröschel C
  6. Mayer-Pröschel M
  A novel mouse model for Ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden.; Human molecular genetics. 2015 Aug 26.
• 1. Tanner DC
  2. Campbell A
  3. O'Banion KM
  4. Noble M
  5. Mayer-Pröschel M
  cFLIP is critical for oligodendrocyte protection from inflammation.; Cell death and differentiation. 2015 Jan 30.
• 1. Noble M
  2. Mayer-Pröschel M
  3. Li Z
  4. Dong T
  5. Cui W
  6. Pröschel C
  7. Ambeskovic I
  8. Dietrich J
  9. Han R
  10. Miranda Yang Y
  11. Folts C
  12. Stripay J
  13. Chen HY
  14. Stevens BM
  Redox biology in normal cells and cancer: Restoring function of the redox/Fyn/c-Cbl pathway in cancer cells offers new approaches to cancer treatment.; Free radical biology & medicine. 2014 Dec 3.
• 1. Stevens BM
  2. Folts CJ
  3. Cui W
  4. Bardin AL
  5. Walter K
  6. Carson-Walter E
  7. Vescovi A
  8. Noble M
  Cool-1-mediated inhibition of c-Cbl modulates multiple critical properties of glioblastomas, including the ability to generate tumors in vivo.; Stem cells (Dayton, Ohio); Vol 32(5). 2014 May.
• 1. Proschel C
  2. Stripay JL
  3. Shih CH
  4. Munger JC
  5. Noble MD
  Delayed transplantation of precursor cell-derived astrocytes provides multiple benefits in a rat model of Parkinsons.; EMBO molecular medicine; Vol 6(4). 2014 Apr.
• 1. Wang J
  2. Bushman J
  3. Wang X
  4. Mayer-Proschel M
  5. Johnson M
  6. Noble M
  Oligodendrocyte/type-2 astrocyte progenitor cells and glial-restricted precursor cells generate different tumor phenotypes in response to the identical oncogenes.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 33(42). 2013 Oct 16.
• 1. Chen HY
  2. Yang YM
  3. Han R
  4. Noble M
  MEK1/2 inhibition suppresses tamoxifen toxicity on CNS glial progenitor cells.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 33(38). 2013 Sep 18.
• 1. Noble M
  2. Mayer-Pröschel M
  3. Pröschel C
  iOPs: a new tool for studying myelin pathologies?; Cell stem cell; Vol 12(5). 2013 May 2.
• 1. Chen HY
  2. Yang YM
  3. Stevens BM
  4. Noble M
  Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells.; EMBO molecular medicine; Vol 5(5). 2013 May.
• 1. Noble M
  2. Mayer-Pröschel M
  3. Davies JE
  4. Davies SJ
  5. Pröschel C
  Cell therapies for the central nervous system: how do we identify the best candidates?; Current opinion in neurology; Vol 24(6). 2011 Dec.
• 1. Noble M
  2. Davies JE
  3. Mayer-Pröschel M
  4. Pröschel C
  5. Davies SJ
  Precursor cell biology and the development of astrocyte transplantation therapies: lessons from spinal cord injury.; Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics; Vol 8(4). 2011 Oct.
• 1. Noble M
  2. Pröschel C
  3. Mayer-Pröschel M
  Oxidative-reductionist approaches to stem and progenitor cell function.; Cell stem cell; Vol 8(1). 2011 Jan 7.
• 1. Chen R
  2. Hyrien O
  3. Noble M
  4. Mayer-Pröschel M
  A composite likelihood approach to the analysis of longitudinal clonal data on multitype cellular systems under an age-dependent branching process.; Biostatistics (Oxford, England); Vol 12(1). 2011 Jan.
• 1. Davies SJ
  2. Shih CH
  3. Noble M
  4. Mayer-Proschel M
  5. Davies JE
  6. Proschel C
  Transplantation of specific human astrocytes promotes functional recovery after spinal cord injury.; PloS one; Vol 6(3). 2011.
• 1. Hyrien O
  2. Dietrich J
  3. Noble M
  Mathematical and experimental approaches to identify and predict the effects of chemotherapy on neuroglial precursors.; Cancer research; Vol 70(24). 2010 Dec 15.
• 1. Hyrien O
  2. Chen R
  3. Mayer-Pröschel M
  4. Noble M
  Saddlepoint approximations to the moments of multitype age-dependent branching processes, with applications.; Biometrics; Vol 66(2). 2010 Jun.
• 1. Han R
  2. Yang YM
  3. Dietrich J
  4. Luebke A
  5. Mayer-Pröschel M
  6. Noble M
  Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system.; Journal of biology; Vol 7(4). 2008.
• 1. Davies JE
  2. Pröschel C
  3. Zhang N
  4. Noble M
  5. Mayer-Pröschel M
  6. Davies SJ
  Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury.; Journal of biology; Vol 7(7). 2008.
• 1. Li Z
  2. Dong T
  3. Pröschel C
  4. Noble M
  Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.; PLoS biology; Vol 5(2). 2007 Feb.
• 1. Jordan CT
  2. Guzman ML
  3. Noble M
  Cancer stem cells.; The New England journal of medicine; Vol 355(12). 2006 Sep 21.
• 1. Noble M
  Implications for CNS repair of redox modulation of cell survival, division and differentiation.; Current Alzheimer research; Vol 3(1). 2006 Feb.
• 1. Dietrich J
  2. Han R
  3. Yang Y
  4. Mayer-Pröschel M
  5. Noble M
  CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo.; Journal of biology; Vol 5(7). 2006.
• 1. Davies JE
  2. Huang C
  3. Proschel C
  4. Noble M
  5. Mayer-Proschel M
  6. Davies SJ
  Astrocytes derived from glial-restricted precursors promote spinal cord repair.; Journal of biology; Vol 5(3). 2006.
• 1. Hyrien O
  2. Ambeskovic I
  3. Mayer-Proschel M
  4. Noble M
  5. Yakovlev A
  Stochastic modeling of oligodendrocyte generation in cell culture: model validation with time-lapse data.; Theoretical biology & medical modelling; Vol 3. 2006.
• 1. Noble M
  Ethics in the trenches: a multifaceted analysis of the stem cell debate.; Stem cell reviews; Vol 1(4). 2005 Dec.
• 1. Noble M
  2. Mayer-Pröschel M
  3. Pröschel C
  Redox regulation of precursor cell function: insights and paradoxes.; Antioxidants & redox signaling; Vol 7(11-12). 2005 Nov.
• 1. Hyrien O
  2. Mayer-Pröschel M
  3. Noble M
  4. Yakovlev A
  A stochastic model to analyze clonal data on multi-type cell populations.; Biometrics; Vol 61(1). 2005 Mar.
• 1. Dietrich J
  2. Lacagnina M
  3. Gass D
  4. Richfield E
  5. Mayer-Pröschel M
  6. Noble M
  7. Torres C
  8. Pröschel C
  EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy.; Nature medicine; Vol 11(3). 2005 Mar.
• 1. Hyrien O
  2. Mayer-Pröschel M
  3. Noble M
  4. Yakovlev A
  Estimating the life-span of oligodendrocytes from clonal data on their development in cell culture.; Mathematical biosciences; Vol 193(2). 2005 Feb.
• 1. Noble M
  Neural precursor cells and toxicant action: Addressing the analysis of low-level toxicant exposure; Role of Glia in Neurotoxicity; Vol 2nd Edition, pp. 1-28. 2005 Jan 01.
• 1. Hill CE
  2. Proschel C
  3. Noble M
  4. Mayer-Proschel M
  5. Gensel JC
  6. Beattie MS
  7. Bresnahan JC
  Acute transplantation of glial-restricted precursor cells into spinal cord contusion injuries: survival, differentiation, and effects on lesion environment and axonal regeneration.; Experimental neurology; Vol 190(2). 2004 Dec.
• 1. Noble M
  2. Dietrich J
  The complex identity of brain tumors: emerging concerns regarding origin, diversity and plasticity.; Trends in neurosciences; Vol 27(3). 2004 Mar.
• 1. Noble M
  The possible role of myelin destruction as a precipitating event in Alzheimer's disease.; Neurobiology of aging; Vol 25(1). 2004 Jan.
• 1. Noble M
  2. Pröschel C
  3. Mayer-Pröschel M
  Getting a GR(i)P on oligodendrocyte development.; Developmental biology; Vol 265(1). 2004 Jan 1.
• 1. Biran R
  2. Noble MD
  3. Tresco PA
  Directed nerve outgrowth is enhanced by engineered glial substrates.; Experimental neurology; Vol 184(1). 2003 Nov.
• 1. Noble M
  2. Smith J
  3. Power J
  4. Mayer-Pröschel M
  Redox state as a central modulator of precursor cell function.; Annals of the New York Academy of Sciences; Vol 991. 2003 Jun.
• 1. Noble M
  2. Arhin A
  3. Gass D
  4. Mayer-Pröschel M
  The cortical ancestry of oligodendrocytes: common principles and novel features.; Developmental neuroscience; Vol 25(2-4). 2003 Mar.
• 1. Dietrich J
  2. Noble M
  3. Mayer-Proschel M
  Characterization of A2B5+ glial precursor cells from cryopreserved human fetal brain progenitor cells.; Glia; Vol 40(1). 2002 Oct.
• 1. Power J
  2. Mayer-Pröschel M
  3. Smith J
  4. Noble M
  Oligodendrocyte precursor cells from different brain regions express divergent properties consistent with the differing time courses of myelination in these regions.; Developmental biology; Vol 245(2). 2002 May 15.
• 1. Noble M
  2. Dietrich J
  Intersections between neurobiology and oncology: tumor origin, treatment and repair of treatment-associated damage.; Trends in neurosciences; Vol 25(2). 2002 Feb.
• 1. Gregori N
  2. Pröschel C
  3. Noble M
  4. Mayer-Pröschel M
  The tripotential glial-restricted precursor (GRP) cell and glial development in the spinal cord: generation of bipotential oligodendrocyte-type-2 astrocyte progenitor cells and dorsal-ventral differences in GRP cell function.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 22(1). 2002 Jan 1.
• 1. Mayer-Pröschel M
  2. Morath D
  3. Noble M
  Are hypothyroidism and iron deficiency precursor cell diseases?; Developmental neuroscience; Vol 23(4-5). 2001.
• 1. Noble M
  Can neural stem cells be used to track down and destroy migratory brain tumor cells while also providing a means of repairing tumor-associated damage?; Proceedings of the National Academy of Sciences of the United States of America; Vol 97(23). 2000 Nov 7.