Recent Publications

• 1. Franchini L
  2. Porter JJ
  3. Lueck JD
  4. Orlandi C
  Gz Enhanced Signal Transduction assaY (G Z ESTY) for GPCR deorphanization.; bioRxiv : the preprint server for biology. 2024 Jul 26.
• 1. Porter JJ
  2. Lueck JD
  A cystic fibrosis gene editing approach that is on target.; Molecular therapy. Nucleic acids; Vol 35(2), pp. 102197. 2024 May 08.
• 1. Cisco LA
  2. Sipple MT
  3. Edwards KM
  4. Thornton CA
  5. Lueck JD
  Verapamil mitigates chloride and calcium bi-channelopathy in a myotonic dystrophy mouse model.; The Journal of clinical investigation; Vol 134(1). 2024 Jan 02.
• 1. Cisco LA
  2. Sipple MT
  3. Edwards KM
  4. Thornton CA
  5. Lueck JD
  Combinatorial chloride and calcium channelopathy in myotonic dystrophy.; bioRxiv : the preprint server for biology. 2023 Jun 01.
• 1. Allaire NE
  2. Griesenbach U
  3. Kerem B
  4. Lueck JD
  5. Stanleigh N
  6. Oren YS
  Gene, RNA, and ASO-based therapeutic approaches in Cystic Fibrosis.; Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 2023 Jan 17.
• 1. Rook ML
  2. McCullock TW
  3. Couch T
  4. Lueck JD
  5. MacLean DM
  Photomodulation of the ASIC1a acidic pocket destabilizes the open state.; Protein science : a publication of the Protein Society. 2023 Jan 08.
• 1. Ko W
  2. Porter JJ
  3. Sipple MT
  4. Edwards KM
  5. Lueck JD
  Efficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs.; Molecular therapy. Nucleic acids; Vol 28. 2022 Jun 14.
• 1. Porter JJ
  2. Heil CS
  3. Lueck JD
  Therapeutic promise of engineered nonsense suppressor tRNAs.; Wiley interdisciplinary reviews. RNA. 2021 Feb 10.
• 1. Rook ML
  2. Williamson A
  3. Lueck JD
  4. Musgaard M
  5. Maclean DM
  β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery.; eLife; Vol 9. 2020 Feb 07.
• 1. Lueck JD
  2. Yoon JS
  3. Perales-Puchalt A
  4. Mackey AL
  5. Infield DT
  6. Behlke MA
  7. Pope MR
  8. Weiner DB
  9. Skach WR
  10. McCray PB
  11. Ahern CA
  Engineered transfer RNAs for suppression of premature termination codons.; Nature communications; Vol 10(1). 2019 Feb 18.
• 1. Molinarolo S
  2. Lee S
  3. Leisle L
  4. Lueck JD
  5. Granata D
  6. Carnevale V
  7. Ahern CA
  Cross-kingdom auxiliary subunit modulation of a voltage-gated sodium channel.; The Journal of biological chemistry; Vol 293(14). 2018 Apr 06.
• 1. Infield DT
  2. Lueck JD
  3. Galpin JD
  4. Galles GD
  5. Ahern CA
  Orthogonality of Pyrrolysine tRNA in the Xenopus oocyte.; Scientific reports; Vol 8(1). 2018 Mar 26.
• 1. Leisle L
  2. Chadda R
  3. Lueck JD
  4. Infield DT
  5. Galpin JD
  6. Krishnamani V
  7. Robertson JL
  8. Ahern CA
  Cellular encoding of Cy dyes for single-molecule imaging.; eLife; Vol 5. 2016 Jan 12.
• 1. Lueck JD
  2. Mackey AL
  3. Infield DT
  4. Galpin JD
  5. Li J
  6. Roux B
  7. Ahern CA
  Atomic mutagenesis in ion channels with engineered stoichiometry.; eLife; Vol 5. 2016 Jan 06.
• 1. Beedle AM
  2. Turner AJ
  3. Saito Y
  4. Lueck JD
  5. Foltz SJ
  6. Fortunato MJ
  7. Nienaber PM
  8. Campbell KP
  Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy.; The Journal of clinical investigation; Vol 122(9). 2012 Sep.
• 1. Loy RE
  2. Lueck JD
  3. Mostajo-Radji MA
  4. Carrell EM
  5. Dirksen RT
  Allele-specific gene silencing in two mouse models of autosomal dominant skeletal myopathy.; PloS one; Vol 7(11). 2012.
• 1. Han R
  2. Frett EM
  3. Levy JR
  4. Rader EP
  5. Lueck JD
  6. Bansal D
  7. Moore SA
  8. Ng R
  9. Beltrán-Valero de Bernabé D
  10. Faulkner JA
  11. Campbell KP
  Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient mice.; The Journal of clinical investigation; Vol 120(12). 2010 Dec.
• 1. Lueck JD
  2. Rossi AE
  3. Thornton CA
  4. Campbell KP
  5. Dirksen RT
  Sarcolemmal-restricted localization of functional ClC-1 channels in mouse skeletal muscle.; The Journal of general physiology; Vol 136(6). 2010 Dec.
• 1. Wheeler TM
  2. Sobczak K
  3. Lueck JD
  4. Osborne RJ
  5. Lin X
  6. Dirksen RT
  7. Thornton CA
  Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA.; Science (New York, N.Y.); Vol 325(5938). 2009 Jul 17.
• 1. Kimura T
  2. Lueck JD
  3. Harvey PJ
  4. Pace SM
  5. Ikemoto N
  6. Casarotto MG
  7. Dirksen RT
  8. Dulhunty AF
  Alternative splicing of RyR1 alters the efficacy of skeletal EC coupling.; Cell calcium; Vol 45(3). 2009 Mar.
• 1. Wheeler TM
  2. Lueck JD
  3. Swanson MS
  4. Dirksen RT
  5. Thornton CA
  Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy.; The Journal of clinical investigation; Vol 117(12). 2007 Dec.
• 1. Lueck JD
  2. Lungu C
  3. Mankodi A
  4. Osborne RJ
  5. Welle SL
  6. Dirksen RT
  7. Thornton CA
  Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1.; American journal of physiology. Cell physiology; Vol 292(4). 2007 Apr.
• 1. Lueck JD
  2. Mankodi A
  3. Swanson MS
  4. Thornton CA
  5. Dirksen RT
  Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy.; The Journal of general physiology; Vol 129(1). 2007 Jan.
• 1. Chelu MG
  2. Goonasekera SA
  3. Durham WJ
  4. Tang W
  5. Lueck JD
  6. Riehl J
  7. Pessah IN
  8. Zhang P
  9. Bhattacharjee MB
  10. Dirksen RT
  11. Hamilton SL
  Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 20(2). 2006 Feb.
• 1. Kimura T
  2. Nakamori M
  3. Lueck JD
  4. Pouliquin P
  5. Aoike F
  6. Fujimura H
  7. Dirksen RT
  8. Takahashi MP
  9. Dulhunty AF
  10. Sakoda S
  Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.; Human molecular genetics; Vol 14(15). 2005 Aug 1.