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Looney Lab

Therapeutic Targeting of Senescent Cells in Lupus

Targeting senescent cells in patients with lupus presents a potential novel approach to disease management and improved clinical outcomes.  While it is known that lupus patients possess cells with a senescence-like phenotype, it is unknown whether these cells would respond to available senolytic drugs.  Studying the effects of these drugs in vitro using patient and lupus mouse model samples will further fundamental insights into the potential role of senolytic drugs in the treatment of lupus.

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Richard John Looney, M.D.

Richard John Looney, M.D.
Principal Investigator

May 23, 2025
AIR Research Presented at the 2025 AAI Meeting

May 23, 2025
Dr. Javier Rangel-Moreno Lecturer at the 2025 Course of Biomedicine and Immunology

January 15, 2025
ROChester Stimulating Access to Research during Residency (ROC StARR) Health and Immune Function Across the Lifespan to Begin July 1st

January 6, 2025
Jennifer Anolik Named Chief of Allergy, Immunology and Rheumatology Division

December 13, 2024
Ilana Abeles Receives Clinical Trial Investigator Award

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  Looney Lab
601 Elmwood Ave/Box 695
Rochester, NY 14642