Recent Publications

• 1. Kroesbergen E
  2. Riesselmann LV
  3. Gomolka RS
  4. Plá V
  5. Esmail T
  6. Stenmo VH
  7. Kovács ER
  8. Nielsen ES
  9. Goldman SA
  10. Nedergaard M
  11. Weikop P
  12. Mori Y
  Glymphatic clearance is enhanced during sleep.; bioRxiv : the preprint server for biology. 2024 Sep 15.
• 1. Kaag Rasmussen M
  2. Møllgård K
  3. Bork PAR
  4. Weikop P
  5. Esmail T
  6. Drici L
  7. Wewer Albrechtsen NJ
  8. Carlsen JF
  9. Huynh NPT
  10. Ghitani N
  11. Mann M
  12. Goldman SA
  13. Mori Y
  14. Chesler AT
  15. Nedergaard M
  Trigeminal ganglion neurons are directly activated by influx of CSF solutes in a migraine model.; Science (New York, N.Y.); Vol 385(6704), pp. 80-86. 2024 Jul 04.
• 1. Mariani JN
  2. Mansky B
  3. Madsen PM
  4. Salinas D
  5. Kesmen D
  6. Huynh NPT
  7. Kuypers NJ
  8. Kesel ER
  9. Bates J
  10. Payne C
  11. Chandler-Militello D
  12. Benraiss A
  13. Goldman SA
  Repression of developmental transcription factor networks triggers aging-associated gene expression in human glial progenitor cells.; Nature communications; Vol 15(1), pp. 3873. 2024 May 08.
• 1. Franklin RJM
  2. Bodini B
  3. Goldman SA
  Remyelination in the Central Nervous System.; Cold Spring Harbor perspectives in biology. 2024 Feb 05.
• 1. Patel KS
  2. Tessema KK
  3. Kawaguchi R
  4. Dudley L
  5. Alvarado AG
  6. Muthukrishnan SD
  7. Perryman T
  8. Hagiwara A
  9. Swarup V
  10. Liau LM
  11. Wang AC
  12. Yong W
  13. Geschwind DH
  14. Nakano I
  15. Goldman SA
  16. Everson RG
  17. Ellingson BM
  18. Kornblum HI
  Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma.; Neuro-oncology advances; Vol 6(1), pp. vdae005. 2024 Jan 25.
• 1. Zhao L
  2. Qiu Z
  3. Yang Z
  4. Xu L
  5. Pearce TM
  6. Wu Q
  7. Yang K
  8. Li F
  9. Saulnier O
  10. Fei F
  11. Yu H
  12. Gimple RC
  13. Varadharajan V
  14. Liu J
  15. Hendrikse LD
  16. Fong V
  17. Wang W
  18. Zhang J
  19. Lv D
  20. Lee D
  21. Lehrich BM
  22. Jin C
  23. Ouyang L
  24. Dixit D
  25. Wu H
  26. Wang X
  27. Sloan AE
  28. Wang X
  29. Huan T
  30. Mark Brown J
  31. Goldman SA
  32. Taylor MD
  33. Zhou S
  34. Rich JN
  Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.; Nature cancer. 2024 Jan 03.
• 1. Goldman SA
  2. Franklin RJM
  3. Osorio J
  Stem and progenitor cell-based therapy of myelin disorders.; Handbook of clinical neurology; Vol 205, pp. 283-295. 2024.
• 1. Takasugi M
  2. Ohtani N
  3. Takemura K
  4. Emmrich S
  5. Zakusilo FT
  6. Yoshida Y
  7. Kutsukake N
  8. Mariani JN
  9. Windrem MS
  10. Chandler-Militello D
  11. Goldman SA
  12. Satoh J
  13. Ito S
  14. Seluanov A
  15. Gorbunova V
  CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.; Cell reports; Vol 42(9), pp. 113130. 2023 Sep 13.
• 1. Vieira R
  2. Mariani JN
  3. Huynh NPT
  4. Stephensen HJT
  5. Solly R
  6. Tate A
  7. Schanz S
  8. Cotrupi N
  9. Mousaei M
  10. Sporring J
  11. Benraiss A
  12. Goldman SA
  Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain.; Nature biotechnology. 2023 Jul 17.
• 1. Villanueva CB
  2. Stephensen HJT
  3. Mokso R
  4. Benraiss A
  5. Sporring J
  6. Goldman SA
  Astrocytic engagement of the corticostriatal synaptic cleft is disrupted in a mouse model of Huntington's disease.; Proceedings of the National Academy of Sciences of the United States of America; Vol 120(24), pp. e2210719120. 2023 Jun 06.
• 1. Stogsdill JA
  2. Harwell CC
  3. Goldman SA
  Astrocytes as master modulators of neural networks: Synaptic functions and disease-associated dysfunction of astrocytes.; Annals of the New York Academy of Sciences. 2023 May 23.
• 1. Khakh BS
  2. Goldman SA
  Astrocytic contributions to Huntington's disease pathophysiology.; Annals of the New York Academy of Sciences; Vol 1522(1), pp. 42-59. 2023 Mar 02.
• 1. Hussain R
  2. Tithof J
  3. Wang W
  4. Cheetham-West A
  5. Song W
  6. Peng W
  7. Sigurdsson B
  8. Kim D
  9. Sun Q
  10. Peng S
  11. Plá V
  12. Kelley DH
  13. Hirase H
  14. Castorena-Gonzalez JA
  15. Weikop P
  16. Goldman SA
  17. Davis MJ
  18. Nedergaard M
  Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema.; Nature. 2023 Jan 15.
• 1. Alvarado AG
  2. Tessema K
  3. Muthukrishnan SD
  4. Sober M
  5. Kawaguchi R
  6. Laks DR
  7. Bhaduri A
  8. Swarup V
  9. Nathanson DA
  10. Geschwind DH
  11. Goldman SA
  12. Kornblum HI
  Pathway-based approach reveals differential sensitivity to E2F1 inhibition in glioblastoma.; Cancer research communications; Vol 2(9), pp. 1049-1060. 2022 Sep 22.
• 1. Wang X
  2. Delle C
  3. Asiminas A
  4. Akther S
  5. Vittani M
  6. Brøgger P
  7. Kusk P
  8. Vo CT
  9. Radovanovic T
  10. Konno A
  11. Hirai H
  12. Fukuda M
  13. Weikop P
  14. Goldman SA
  15. Nedergaard M
  16. Hirase H
  Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation.; Cell reports methods; Vol 2(10), pp. 100302. 2022 Sep 21.
• 1. Benraiss A
  2. Mariani JN
  3. Tate A
  4. Madsen PM
  5. Clark KM
  6. Welle KA
  7. Solly R
  8. Capellano L
  9. Bentley K
  10. Chandler-Militello D
  11. Goldman SA
  A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice.; Cell reports; Vol 40(9), pp. 111291. 2022 Aug 30.
• 1. Rosser AE
  2. Busse ME
  3. Gray WP
  4. Badin RA
  5. Perrier AL
  6. Wheelock V
  7. Cozzi E
  8. Martin UP
  9. Salado-Manzano C
  10. Mills LJ
  11. Drew C
  12. Goldman SA
  13. Canals JM
  14. Thompson LM
  Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder.; Brain : a journal of neurology; Vol 145(5). 2022 Jun 03.
• 1. Muthukrishnan SD
  2. Kawaguchi R
  3. Nair P
  4. Prasad R
  5. Qin Y
  6. Johnson M
  7. Wang Q
  8. VanderVeer-Harris N
  9. Pham A
  10. Alvarado AG
  11. Condro MC
  12. Gao F
  13. Gau R
  14. Castro MG
  15. Lowenstein PR
  16. Deb A
  17. Hinman JD
  18. Pajonk F
  19. Burns TC
  20. Goldman SA
  21. Geschwind DH
  22. Kornblum HI
  P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells.; Nature communications; Vol 13(1), pp. 6202. 2022 Jan 19.
• 1. Ghochani Y
  2. Muthukrishnan SD
  3. Sohrabi A
  4. Kawaguchi R
  5. Condro MC
  6. Bastola S
  7. Gao F
  8. Qin Y
  9. Mottahedeh J
  10. Iruela-Arispe ML
  11. Rao N
  12. Laks DR
  13. Liau LM
  14. Mathern GW
  15. Goldman SA
  16. Carmichael ST
  17. Nakano I
  18. Coppola G
  19. Seidlits SK
  20. Kornblum HI
  A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration.; Cell reports; Vol 41(3), pp. 111511. 2022 Jan 18.
• 1. Osorio MJ
  2. Mariani JN
  3. Zou L
  4. Schanz SJ
  5. Heffernan K
  6. Cornwell A
  7. Goldman SA
  Glial progenitor cells of the adult human white and grey matter are contextually distinct.; Glia. 2022 Jan 05.
• 1. Benraiss A
  2. Mariani JN
  3. Osipovitch M
  4. Cornwell A
  5. Windrem MS
  6. Villanueva CB
  7. Chandler-Militello D
  8. Goldman SA
  Cell-intrinsic glial pathology is conserved across human and murine models of Huntington's disease.; Cell reports; Vol 36(1). 2021 Jul 06.
• 1. Li J
  2. Pan L
  3. Pembroke WG
  4. Rexach JE
  5. Godoy MI
  6. Condro MC
  7. Alvarado AG
  8. Harteni M
  9. Chen YW
  10. Stiles L
  11. Chen AY
  12. Wanner IB
  13. Yang X
  14. Goldman SA
  15. Geschwind DH
  16. Kornblum HI
  17. Zhang Y
  Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes.; Nature communications; Vol 12(1). 2021 Jun 25.
• 1. Park HJ
  2. Jeon J
  3. Choi J
  4. Kim JY
  5. Kim HS
  6. Huh JY
  7. Goldman SA
  8. Song J
  Human iPSC-derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model.; Cell proliferation. 2021 Jun 21.
• 1. Hyun I
  2. Clayton EW
  3. Cong Y
  4. Fujita M
  5. Goldman SA
  6. Hill LR
  7. Monserrat N
  8. Nakauchi H
  9. Pedersen RA
  10. Rooke HM
  11. Takahashi J
  12. Knoblich JA
  ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts.; Stem cell reports; Vol 16(6). 2021 Jun 08.
• 1. Lovell-Badge R
  2. Anthony E
  3. Barker RA
  4. Bubela T
  5. Brivanlou AH
  6. Carpenter M
  7. Charo RA
  8. Clark A
  9. Clayton E
  10. Cong Y
  11. Daley GQ
  12. Fu J
  13. Fujita M
  14. Greenfield A
  15. Goldman SA
  16. Hill L
  17. Hyun I
  18. Isasi R
  19. Kahn J
  20. Kato K
  21. Kim JS
  22. Kimmelman J
  23. Knoblich JA
  24. Mathews D
  25. Montserrat N
  26. Mosher J
  27. Munsie M
  28. Nakauchi H
  29. Naldini L
  30. Naughton G
  31. Niakan K
  32. Ogbogu U
  33. Pedersen R
  34. Rivron N
  35. Rooke H
  36. Rossant J
  37. Round J
  38. Saitou M
  39. Sipp D
  40. Steffann J
  41. Sugarman J
  42. Surani A
  43. Takahashi J
  44. Tang F
  45. Turner L
  46. Zettler PJ
  47. Zhai X
  ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.; Stem cell reports. 2021 May 25.
• 1. Kim KP
  2. Li C
  3. Bunina D
  4. Jeong HW
  5. Ghelman J
  6. Yoon J
  7. Shin B
  8. Park H
  9. Han DW
  10. Zaugg JB
  11. Kim J
  12. Kuhlmann T
  13. Adams RH
  14. Noh KM
  15. Goldman SA
  16. Schöler HR
  Donor cell memory confers a metastable state of directly converted cells.; Cell stem cell. 2021 Apr 07.
• 1. Escartin C
  2. Galea E
  3. Lakatos A
  4. O'Callaghan JP
  5. Petzold GC
  6. Serrano-Pozo A
  7. Steinhäuser C
  8. Volterra A
  9. Carmignoto G
  10. Agarwal A
  11. Allen NJ
  12. Araque A
  13. Barbeito L
  14. Barzilai A
  15. Bergles DE
  16. Bonvento G
  17. Butt AM
  18. Chen WT
  19. Cohen-Salmon M
  20. Cunningham C
  21. Deneen B
  22. De Strooper B
  23. Díaz-Castro B
  24. Farina C
  25. Freeman M
  26. Gallo V
  27. Goldman JE
  28. Goldman SA
  29. Götz M
  30. Gutiérrez A
  31. Haydon PG
  32. Heiland DH
  33. Hol EM
  34. Holt MG
  35. Iino M
  36. Kastanenka KV
  37. Kettenmann H
  38. Khakh BS
  39. Koizumi S
  40. Lee CJ
  41. Liddelow SA
  42. MacVicar BA
  43. Magistretti P
  44. Messing A
  45. Mishra A
  46. Molofsky AV
  47. Murai KK
  48. Norris CM
  49. Okada S
  50. Oliet SHR
  51. Oliveira JF
  52. Panatier A
  53. Parpura V
  54. Pekna M
  55. Pekny M
  56. Pellerin L
  57. Perea G
  58. Pérez-Nievas BG
  59. Pfrieger FW
  60. Poskanzer KE
  61. Quintana FJ
  62. Ransohoff RM
  63. Riquelme-Perez M
  64. Robel S
  65. Rose CR
  66. Rothstein JD
  67. Rouach N
  68. Rowitch DH
  69. Semyanov A
  70. Sirko S
  71. Sontheimer H
  72. Swanson RA
  73. Vitorica J
  74. Wanner IB
  75. Wood LB
  76. Wu J
  77. Zheng B
  78. Zimmer ER
  79. Zorec R
  80. Sofroniew MV
  81. Verkhratsky A
  Reactive astrocyte nomenclature, definitions, and future directions.; Nature neuroscience. 2021 Feb 15.
• 1. Goldman SA
  2. Mariani JN
  3. Madsen PM
  Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic.; Seminars in cell & developmental biology. 2021 Jan 04.
• 1. Feng L
  2. Chao J
  3. Tian E
  4. Li L
  5. Ye P
  6. Zhang M
  7. Chen X
  8. Cui Q
  9. Sun G
  10. Zhou T
  11. Felix G
  12. Qin Y
  13. Li W
  14. Meza ED
  15. Klein J
  16. Ghoda L
  17. Hu W
  18. Luo Y
  19. Dang W
  20. Hsu D
  21. Gold J
  22. Goldman SA
  23. Matalon R
  24. Shi Y
  Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs.; Advanced science (Weinheim, Baden-Wurttemberg, Germany); Vol 7(23). 2020 Dec.
• 1. Nedergaard M
  2. Goldman SA
  Glymphatic failure as a final common pathway to dementia.; Science (New York, N.Y.); Vol 370(6512). 2020 Oct 02.
• 1. Zeng J
  2. Dong S
  3. Luo Z
  4. Xie X
  5. Fu B
  6. Li P
  7. Liu C
  8. Yang X
  9. Chen Y
  10. Wang X
  11. Liu Z
  12. Wu J
  13. Yan Y
  14. Wang F
  15. Chen JF
  16. Zhang J
  17. Long G
  18. Goldman SA
  19. Li S
  20. Zhao Z
  21. Liang Q
  The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis.; Cell stem cell. 2020 Aug 04.
• 1. Goldman SA
  Glial evolution as a determinant of human behavior and its disorders.; Annals of the New York Academy of Sciences; Vol 1471(1). 2020 Jul.
• 1. Windrem MS
  2. Schanz SJ
  3. Zou L
  4. Chandler-Militello D
  5. Kuypers NJ
  6. Nedergaard M
  7. Lu Y
  8. Mariani JN
  9. Goldman SA
  Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain.; Cell reports; Vol 31(7). 2020 May 19.
• 1. Nolbrant S
  2. Giacomoni J
  3. Hoban DB
  4. Bruzelius A
  5. Birtele M
  6. Chandler-Militello D
  7. Pereira M
  8. Ottosson DR
  9. Goldman SA
  10. Parmar M
  Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons.; Stem cell reports; Vol 15(4). 2020 Jan 13.
• 1. Dietz AG
  2. Goldman SA
  3. Nedergaard M
  Glial cells in schizophrenia: a unified hypothesis.; The lancet. Psychiatry. 2019 Nov 05.
• 1. Nobuta H
  2. Yang N
  3. Ng YH
  4. Marro SG
  5. Sabeur K
  6. Chavali M
  7. Stockley JH
  8. Killilea DW
  9. Walter PB
  10. Zhao C
  11. Huie P
  12. Goldman SA
  13. Kriegstein AR
  14. Franklin RJM
  15. Rowitch DH
  16. Wernig M
  Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation.; Cell stem cell; Vol 25(4). 2019 Oct 03.
• 1. Liu Z
  2. Osipovitch M
  3. Benraiss A
  4. Huynh NPT
  5. Foti R
  6. Bates J
  7. Chandler-Militello D
  8. Findling RL
  9. Tesar PJ
  10. Nedergaard M
  11. Windrem MS
  12. Goldman SA
  Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling.; Cell reports; Vol 27(13). 2019 Jun 25.
• 1. Osipovitch M
  2. Asenjo Martinez A
  3. Mariani JN
  4. Cornwell A
  5. Dhaliwal S
  6. Zou L
  7. Chandler-Militello D
  8. Wang S
  9. Li X
  10. Benraiss SJ
  11. Agate R
  12. Lampp A
  13. Benraiss A
  14. Windrem MS
  15. Goldman SA
  Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation.; Cell stem cell; Vol 24(1). 2019 Jan 03.
• 1. Mariani JN
  2. Zou L
  3. Goldman SA
  Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease.; Methods in molecular biology (Clifton, N.J.); Vol 1936. 2019.
• 1. Wang M
  2. Qin C
  3. Luo X
  4. Wang J
  5. Wang X
  6. Xie M
  7. Hu J
  8. Cao J
  9. Hu T
  10. Goldman SA
  11. Nedergaard M
  12. Wang W
  Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease.; Theranostics; Vol 9(15). 2019.
• 1. Barker RA
  2. Carpenter MK
  3. Forbes S
  4. Goldman SA
  5. Jamieson C
  6. Murry CE
  7. Takahashi J
  8. Weir G
  The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?; Stem cell reports; Vol 10(5). 2018 May 08.
• 1. Goldman SA
  Transplanted neural progenitors bridge gaps to benefit cord-injured monkeys.; Nature medicine; Vol 24(4). 2018 Apr 10.
• 1. Osório MJ
  2. Goldman SA
  Neurogenetics of Pelizaeus-Merzbacher disease.; Handbook of clinical neurology; Vol 148. 2018.
• 1. Goldman SA
  Patience pays in spinal repair.; The Journal of clinical investigation; Vol 127(9). 2017 Sep 01.
• 1. Windrem MS
  2. Osipovitch M
  3. Liu Z
  4. Bates J
  5. Chandler-Militello D
  6. Zou L
  7. Munir J
  8. Schanz S
  9. McCoy K
  10. Miller RH
  11. Wang S
  12. Nedergaard M
  13. Findling RL
  14. Tesar PJ
  15. Goldman SA
  Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia.; Cell stem cell; Vol 21(2). 2017 Aug 03.
• 1. Khakh BS
  2. Beaumont V
  3. Cachope R
  4. Munoz-Sanjuan I
  5. Goldman SA
  6. Grantyn R
  Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease.; Trends in neurosciences; Vol 40(7). 2017 Jul.
• 1. Sun W
  2. Cornwell A
  3. Li J
  4. Peng S
  5. Osorio MJ
  6. Aalling N
  7. Wang S
  8. Benraiss A
  9. Lou N
  10. Goldman SA
  11. Nedergaard M
  SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 37(17). 2017 Apr 26.
• 1. Nevin ZS
  2. Factor DC
  3. Karl RT
  4. Douvaras P
  5. Laukka J
  6. Windrem MS
  7. Goldman SA
  8. Fossati V
  9. Hobson GM
  10. Tesar PJ
  Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes.; American journal of human genetics; Vol 100(4). 2017 Apr 06.
• 1. Osorio MJ
  2. Rowitch DH
  3. Tesar P
  4. Wernig M
  5. Windrem MS
  6. Goldman SA
  Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease.; Stem cells (Dayton, Ohio); Vol 35(2). 2017 Feb.
• 1. Goldman SA
  Progenitor cell-based treatment of glial disease.; Progress in brain research; Vol 231. 2017.