URMC / Labs / Georas Lab / Publications Recent Publications Khurana SGeoras SN Stepping down biologics in asthma: is it time to challenge the status quo?; The European respiratory journal; Vol 64(2). 2024 Aug 22. Rimmer CHetelekides SEliseeva SIGeoras SNVeazey JM Correction: Budesonide promotes airway epithelial barrier integrity following double-stranded RNA challenge.; PloS one; Vol 19(7), pp. e0306666. 2024 Jul 01. Canaday FTGeoras SNCroft DP Examining the impact of air pollution, climate change, and social determinants of health on asthma and environmental justice.; Current opinion in pulmonary medicine. 2024 Feb 27. Georas SNKhurana S Update on Asthma Biology.; The Journal of allergy and clinical immunology. 2024 Feb 08. Baugh AAdegunsoye AConnolly MCroft DPew KMcCormack MCGeoras SN Response.; Chest; Vol 165(2), pp. e62-e63. 2024 Feb. Baugh AAdegunsoye AConnolly MCroft DPew KMcCormack MCGeoras SN Towards a Race-Neutral System of Pulmonary Function Test Results Interpretation.; Chest. 2023 Jun 17. Connolly MJDonohue PAPalli RKhurana SCai XGeoras SN Diagnostic Impact of a Race-Composite Pulmonary Function Test Results Interpretation Strategy.; Chest. 2023 Jun 17. Beck LAPesonen MThakar JGeoras SNJärvinen KM IgE Sensitization Drives the Atopic March.; American journal of respiratory and critical care medicine. 2022 Jan 08. Donohue PLove NCConnolly MKhurana SGeoras SN The effects of a deep breathing maneuver on standard airwave oscillometry measurements.; Respiratory medicine and research; Vol 83, pp. 100985. 2022 Jan 06. Veazey JMWong GSEliseeva SISmyth TRChapman TJLim KKim MGeoras SN Protein kinase D3 promotes neutrophil migration during viral infection.; Immunology and cell biology. 2022 Jan 01. O'Dell CTBoule LARobert JGeoras SNEliseeva SLawrence BP Exposure to a mixture of 23 chemicals associated with unconventional oil and gas operations alters immune response to challenge in adult mice.; Journal of immunotoxicology; Vol 18(1). 2021 Dec. Georas SNWright RJIvanova AIsrael ELaVange LMAkuthota PCarr TFDenlinger LCFajt MLKumar RO'Neal WKPhipatanakul WSzefler SJAronica MABacharier LBBurbank AJCastro MAlexander LCBamdad JCardet JCComhair SAACovar RADiMango EAErwin KErzurum SCFahy JVGaffin JMGaston BGerald LBHoffman EAHolguin FJackson DJJames JJarjour NNKenyon NJKhatri SKirwan JPKraft MKrishnan JALiu AHLiu MCMarquis MAMartinez FMey JMoore WCMoy JNOrtega VEPeden DBPennington EPeters MCRoss KSanchez MSmith LJSorkness RLWechsler MEWenzel SEWhite SRZein JZeki AANoel P The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: an overview of Network organization, procedures and interventions.; The Journal of allergy and clinical immunology. 2021 Nov 27. Georas SNDonohue PConnolly MWechsler ME JAK inhibitors for asthma.; The Journal of allergy and clinical immunology; Vol 148(4). 2021 Oct. Georas SN Inhaled Adjuvants and Eosinophilic Airway Inflammation in Asthma: Is a Little Bit of Lipopolysaccharide the Key to Allergen Sensitization?; Journal of immunology (Baltimore, Md. : 1950); Vol 207(7). 2021 Oct 01. Croft DPBurton DSNagel DJBhattacharya SFalsey ARGeoras SNHopke PKJohnston CJKottmann RMLitonjua AAMariani TJRich DQThevenet-Morrison KThurston SWUtell MJMcCall MN The effect of air pollution on the transcriptomics of the immune response to respiratory infection.; Scientific reports; Vol 11(1). 2021 Sep 30. Abbas FGeoras SCai XKhurana S Asthma Biologics: Real-World Effectiveness, Impact of Switching Biologics and Predictors of Response.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 Sep 02. Smyth TGeoras SN Effects of ozone and particulate matter on airway epithelial barrier structure and function: a review of in vitro and in vivo studies.; Inhalation toxicology. 2021 Aug 04. Georas SN LPA and Autotaxin: Potential Drug Targets in Asthma?; Cell biochemistry and biophysics. 2021 Jul 31. Israel EDenlinger LCBacharier LBLaVange LMMoore WCPeters MCGeoras SNWright RJMauger DTNoel PAkuthota PBach JBleecker ERCardet JCCarr TFCastro MCinelli AComhair SAACovar RAAlexander LCDiMango EAErzurum SCFahy JVFajt MLGaston BMHoffman EAHolguin FJackson DJJain SJarjour NNJi YKenyon NJKosorok MRKraft MKrishnan JAKumar RLiu AHLiu MCLy NPMarquis MAMartinez FDMoy JNO'Neal WKOrtega VEPeden DBPhipatanakul WRoss KSmith LJSzefler SJTeague WGTulchinsky AFVijayanand PWechsler MEWenzel SEWhite SRZeki AAIvanova A PrecISE: Precision Medicine in Severe Asthma An Adaptive Platform Trial with Biomarker Ascertainment.; The Journal of allergy and clinical immunology. 2021 Mar 02. Eliseeva SIKnowlden ZALester GMDean DAGeoras SNChapman TJ Changes in lung immune cell infiltrates after electric field treatment in mice.; Scientific reports; Vol 11(1). 2021 Jan 14. Zhang PLopez RAttaway AHGeoras SNKhatri SBAbi-Saleh SZein JG Diabetes Mellitus is Associated with Worse Outcome in Patients Hospitalized for Asthma.; The journal of allergy and clinical immunology. In practice. 2020 Nov 09. Pariser DNHilt ZTTure SKBlick-Nitko SKLooney MRCleary SJRoman-Pagan ESaunders Ii JGeoras SNVeazey JMMadere FTesoro Santos LArne AMHuynh NPLivada ACGuerrero-Martin SMLyons CEMetcalf Pate KAMcGrath KEPalis JMorrell C Lung megakaryocytes are immune modulatory cells.; The Journal of clinical investigation. 2020 Oct 20. Smyth TVeazey JEliseeva SChalupa DElder AGeoras SN Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin.; Particle and fibre toxicology; Vol 17(1). 2020 Oct 15. Ivanova AIsrael ELaVange LMPeters MCDenlinger LCMoore WCBacharier LBMarquis MAGotman NMKosorok MRTomlinson CMauger DTGeoras SNWright RJNoel PRosner GLAkuthota PBillheimer DBleecker ERCardet JCCastro MDiMango EAErzurum SCFahy JVFajt MLGaston BMHolguin FJain SKenyon NJKrishnan JAKraft MKumar RLiu MCLy NPMoy JNPhipatanakul WRoss KSmith LJSzefler SJTeague WGWechsler MEWenzel SEWhite SR The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations.; Journal of biopharmaceutical statistics. 2020 Sep 17. Baah SGeoras SN Treatment for Pneumothorax.; The New England journal of medicine; Vol 382(18). 2020 Apr 30. Clark HLValencia HEFindeis-Hosey JJGeoras SN Invasive pulmonary aspergillosis in a patient with cirrhosis.; IDCases; Vol 19. 2020. Veazey JMEliseeva SIHillman SEStiles KSmyth TRMorrissey CETillotson EJTopham DJChapman TJGeoras SN Inhibiting Protein Kinase D Promotes Airway Epithelial Barrier Integrity in Mouse Models of Influenza A Virus Infection.; Frontiers in immunology; Vol 11. 2020. Georas SN Targeting histone deacetylases to restore epithelial barrier integrity: A new option for personalized medicine in patients with allergic airway disorders?; The Journal of allergy and clinical immunology. 2019 Sep 23. Wu EKEliseeva SRahimi HSchwarz EMGeoras SN Restrictive lung disease in TNF-transgenic mice: correlation of pulmonary function testing and micro-CT imaging.; Experimental lung research. 2019 Jul 18. Veazey JMChapman TJSmyth TRHillman SEEliseeva SIGeoras SN Distinct roles for MDA5 and TLR3 in the acute response to inhaled double-stranded RNA.; PloS one; Vol 14(5). 2019. Georas SRansom NHillman SEliseeva SVeazey JSmyth TLe KMeddings J The leaky lung test: A pilot study using inhaled mannitol to measure airway barrier function in asthma.; The Journal of asthma : official journal of the Association for the Care of Asthma. 2018 Nov 16. Boulé LAChapman TJHillman SEKassotis CDO'Dell CRobert JGeoras SNNagel SCLawrence BP Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice.; Toxicological sciences : an official journal of the Society of Toxicology. 2018 May 01. Georas SN All plugged up - noninvasive mucus score to assess airway dysfunction in asthma.; The Journal of clinical investigation; Vol 128(3). 2018 Mar 01. Roto DMalnoske MLWinters SGeoras SN A Fatal Case of Influenza B Myocarditis with Cardiac Tamponade.; Case reports in critical care; Vol 2018. 2018. Long XDaya MZhao JRafaels NLiang HPotee JCampbell MZhang BAraujo MIOliveira RRMathias RAGao LRuczinski IGeoras SNVercelli DBeaty THBarnes KCChen XChen Q The role of ST2 and ST2 genetic variants in schistosomiasis.; The Journal of allergy and clinical immunology; Vol 140(5). 2017 Nov. Li NGeoras SAlexis NFritz PXia TWilliams MAHorner ENel A A work group report on ultrafine particles (American Academy of Allergy, Asthma & Immunology): Why ambient ultrafine and engineered nanoparticles should receive special attention for possible adverse health outcomes in human subjects.; The Journal of allergy and clinical immunology; Vol 138(2). 2016 Aug. Georas SNChapman TJCrouser ED Sarcoidosis and T-Helper Cells. Th1, Th17, or Th17.1?; American journal of respiratory and critical care medicine; Vol 193(11). 2016 Jun 01. Knowlden SAHillman SEChapman TJPatil RMiller DDTigyi GGeoras SN Novel Inhibitory Effect of a Lysophosphatidic Acid 2 Agonist on Allergen-Driven Airway Inflammation.; American journal of respiratory cell and molecular biology; Vol 54(3). 2016 Mar. Becerra AZGeoras SBrenna JTHopke PKKane CChalupa DFrampton MWBlock RRich DQ Increases in ambient particulate matter air pollution, acute changes in platelet function, and effect modification by aspirin and omega-3 fatty acids: A panel study.; Journal of toxicology and environmental health. Part A; Vol 79(6). 2016. Levy BDNoel PJFreemer MMCloutier MMGeoras SNJarjour NNOber CWoodruff PGBarnes KCBender BGCamargo CAChupp GLDenlinger LCFahy JVFitzpatrick AMFuhlbrigge AGaston BMHartert TVKolls JKLynch SVMoore WCMorgan WJNadeau KCOwnby DRSolway JSzefler SJWenzel SEWright RJSmith RAErzurum SC Future Research Directions in Asthma. An NHLBI Working Group Report.; American journal of respiratory and critical care medicine; Vol 192(11). 2015 Dec 1. Georas SNvan Wijngaarden ERich DQ Air pollution and asthma incidence: doubt no more?; The Lancet. Respiratory medicine; Vol 3(12). 2015 Dec. Block RCAbdolahi ATu XGeoras SNBrenna JTPhipps RPLawrence PMousa SA The effects of aspirin on platelet function and lysophosphatidic acids depend on plasma concentrations of EPA and DHA.; Prostaglandins, leukotrienes, and essential fatty acids; Vol 96. 2015 May. Long XChen QZhao JRafaels NMathias PLiang HPotee JCampbell MZhang BGao LGeoras SNVercelli DBeaty THRuczinski IMathias RBarnes KCChen X An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum.; PloS one; Vol 10(8). 2015. Chapman TJGeoras SN Regulatory tone and mucosal immunity in asthma.; International immunopharmacology; Vol 23(1). 2014 Nov. Georas SNRezaee F Epithelial barrier function: at the front line of asthma immunology and allergic airway inflammation.; The Journal of allergy and clinical immunology; Vol 134(3). 2014 Sep. Rezaee FGeoras SN Breaking barriers. New insights into airway epithelial barrier function in health and disease.; American journal of respiratory cell and molecular biology; Vol 50(5). 2014 May. Carlsten CGeoras SN Update in environmental and occupational lung diseases 2013.; American journal of respiratory and critical care medicine; Vol 189(9). 2014 May 1. Abdolahi AGeoras SNBrenna JTCai XThevenet-Morrison KPhipps RPLawrence PMousa SABlock RC The effects of aspirin and fish oil consumption on lysophosphatidylcholines and lysophosphatidic acids and their correlates with platelet aggregation in adults with diabetes mellitus.; Prostaglandins, leukotrienes, and essential fatty acids; Vol 90(2-3). 2014 Feb. Knowlden SGeoras SN The autotaxin-LPA axis emerges as a novel regulator of lymphocyte homing and inflammation.; Journal of immunology (Baltimore, Md. : 1950); Vol 192(3). 2014 Feb 1. Georas SNUpham J Environmental exposures and innate immunity in the lung.; Journal of environmental immunology and toxicology; Vol 2(1). 2014 Jan.