URMC / Labs / Buckley Lab / Publications Recent Publications Kotelsky ACarrier JSBuckley MR Quantification of Cartilage Poroelastic Material Properties Via Analysis of Loading-Induced Cell Death.; Journal of biomechanical engineering; Vol 146(8). 2024 Aug 01. Mora KEMlawer SJLoiselle AEBuckley MR The Micromechanical Environment of the Impinged Achilles Tendon.; Small (Weinheim an der Bergstrasse, Germany). 2024 Jul 05. Ackerman JEAdjei-Sowah EKorcari AMuscat SNNichols AECBuckley MRLoiselle AE Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing.; bioRxiv : the preprint server for biology. 2023 Jul 21. Li HKorcari ACiufo DMendias CLRodeo SABuckley MRLoiselle AEPitt GSCao C Increased Ca2+ signaling through CaV 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 37(7), pp. e23007. 2023 Jul. Korcari ANichols AECBuckley MRLoiselle AE Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype.; eLife; Vol 12. 2023 Jan 19. Ackerman JEMuscat SNAdjei-Sowah EKorcari ANichols AECBuckley MRLoiselle AE Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing.; Matrix biology : journal of the International Society for Matrix Biology. 2023 Jan 13. Wise BCMora KELee WBuckley MR Murine Hind Limb Explant Model for Studying the Mechanobiology of Achilles Tendon Impingement.; Journal of visualized experiments : JoVE. 2023 Jan 08. Korcari ABuckley MRLoiselle AE Characterization of scar tissue biomechanics during adult murine flexor tendon healing.; Journal of the mechanical behavior of biomedical materials; Vol 130. 2022 Mar 23. Kallenbach JGFreeberg MATAbplanalp DAlenchery RGAjalik REMuscat SMyers JAAshton JMLoiselle ABuckley MRvan Wijnen AJAwad HA Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse.; Scientific reports; Vol 12(1). 2022 Feb 22. Aggouras ANChimenti RLSamuel Flemister AKetz JSlane LCBuckley MRRichards MS Impingement in Insertional Achilles Tendinopathy Occurs Across a Larger Range of Ankle Angles and Is Associated With Increased Tendon Thickness.; Foot & ankle international. 2022 Jan 27. Korcari AMuscat SMcGinn EBuckley MRLoiselle AE Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing.; PloS one; Vol 17(10), pp. e0274227. 2022 Jan 14. Mora KEMlawer SJBae AJRichards MSLoiselle AEBuckley MR Ultrasound strain mapping of the mouse Achilles tendon during passive dorsiflexion.; Journal of biomechanics; Vol 132. 2021 Dec 20. Best KTKorcari AMora KENichols AEMuscat SNKnapp EBuckley MRLoiselle AE Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis.; eLife; Vol 10. 2021 Jan 22. Taguchi TKotelsky ATakasugi MChang MKe ZBetancourt MBuckley MRZuscik MSeluanov AGorbunova V Naked mole-rats are extremely resistant to post-traumatic osteoarthritis.; Aging cell. 2020 Oct 28. Bah IFernandes NRJChimenti RLKetz JFlemister ASBuckley MR Tensile mechanical changes in the Achilles tendon due to Insertional Achilles tendinopathy.; Journal of the mechanical behavior of biomedical materials; Vol 112. 2020 Aug 19. Xu MRamirez-Garcia MANarang HBuckley MRLerner ALYoon G Individualized Characterization of the Distribution of Collagen Fibril Dispersion Using Optical Aberrations of the Cornea for Biomechanical Models.; Investigative ophthalmology & visual science; Vol 61(10). 2020 Aug 03. Kotelsky ACarrier JSAggouras ARichards MSBuckley MR Evidence that reduction in volume protects in situ articular chondrocytes from mechanical impact.; Connective tissue research. 2020 Jan 14. Ackerman JEStudentsova VMyers MBuckley MRRichards MSLoiselle AE Non-Invasive Ultrasound Quantification of Scar Tissue Volume Identifies Early Functional Changes During Tendon Healing.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 37(11). 2019 Nov. Stein MJBuckley MRManuele DGutierrez ALoor JSNguyen PKKuo CK Design of a Bioreactor to Assess the Effect of Passive Joint Loading in a Live Chick Embryo In Ovo.; Tissue engineering. Part C, Methods. 2019 Oct 30. Zuskov AFreedman BRGordon JASarver JJBuckley MRSoslowsky LJ Tendon Biomechanics and Crimp Properties Following Fatigue Loading Are Influenced by Tendon Type and Age in Mice.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019 Jul 09. Kotelsky ACarrier JSBuckley MR Real-time Visualization and Analysis of Chondrocyte Injury Due to Mechanical Loading in Fully Intact Murine Cartilage Explants.; Journal of visualized experiments : JoVE. 2019 Jan 07. Ramirez-Garcia MAKhalifa YMBuckley MR Vulnerability of corneal endothelial cells to mechanical trauma from indentation forces assessed using contact mechanics and fluorescence microscopy.; Experimental eye research; Vol 175. 2018 Oct. Studentsova VMora KMGlasner MFBuckley MRLoiselle AE Obesity/Type II Diabetes Promotes Function-limiting Changes in Murine Tendons that are not reversed by Restoring Normal Metabolic Function.; Scientific reports; Vol 8(1). 2018 Jun 15. Freeberg MATFarhat YMEasa AKallenbach JGMalcolm DWBuckley MRBenoit DSWAwad HA Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy.; Scientific reports; Vol 8(1). 2018 Apr 11. Newman HRBowles RDBuckley MR Viscoelastic heating of insulated bovine intervertebral disc.; JOR spine; Vol 1(1). 2018 Mar. Kotelsky AWoo CWDelgadillo LFRichards MSBuckley MR An Alternative Method to Characterize the Quasi-Static, Nonlinear Material Properties of Murine Articular Cartilage.; Journal of biomechanical engineering; Vol 140(1). 2018 Jan 01. Ramirez-Garcia MASloan SRNidenberg BKhalifa YMBuckley MR Depth-Dependent Out-of-Plane Young's Modulus of the Human Cornea.; Current eye research. 2017 Dec 28. Ackerman JEBah IJonason JHBuckley MRLoiselle AE Aging does not alter tendon mechanical properties during homeostasis, but does impair flexor tendon healing.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 35(12). 2017 Dec. Chimenti RLBucklin MKelly MKetz JFlemister ASRichards MSBuckley MR Insertional achilles tendinopathy associated with altered transverse compressive and axial tensile strain during ankle dorsiflexion.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 35(4). 2017 Apr. Chimenti RLChimenti PCBuckley MRHouck JRFlemister AS Utility of Ultrasound for Imaging Osteophytes in Patients With Insertional Achilles Tendinopathy.; Archives of physical medicine and rehabilitation; Vol 97(7). 2016 Jul. Chimenti RLFlemister ASKetz JBucklin MBuckley MRRichards MS Ultrasound strain mapping of Achilles tendon compressive strain patterns during dorsiflexion.; Journal of biomechanics; Vol 49(1). 2016 Jan 4. Bah IKwak STChimenti RLRichards MSP Ketz JSamuel Flemister ABuckley MR Mechanical changes in the Achilles tendon due to insertional Achilles tendinopathy.; Journal of the mechanical behavior of biomedical materials; Vol 53. 2016 Jan. Mienaltowski MJDunkman AABuckley MRBeason DPAdams SMBirk DESoslowsky LJ The injury response of geriatric mouse patellar tendons.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2015 Dec 24. Freedman BRZuskov ASarver JJBuckley MRSoslowsky LJ Evaluating changes in tendon crimp with fatigue loading as an ex vivo structural assessment of tendon damage.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 33(6). 2015 Jun. Griffin DJVicari JBuckley MRSilverberg JLCohen IBonassar LJ Effects of enzymatic treatments on the depth-dependent viscoelastic shear properties of articular cartilage.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society; Vol 32(12). 2014 Dec. Sloan SRKhalifa YMBuckley MR The location- and depth-dependent mechanical response of the human cornea under shear loading.; Investigative ophthalmology & visual science; Vol 55(12). 2014 Dec. Freedman BRSarver JJBuckley MRVoleti PBSoslowsky LJ Biomechanical and structural response of healing Achilles tendon to fatigue loading following acute injury.; Journal of biomechanics; Vol 47(9). 2014 Jun 27. Dunkman AABuckley MRMienaltowski MJAdams SMThomas SJKumar ABeason DPIozzo RVBirk DESoslowsky LJ The injury response of aged tendons in the absence of biglycan and decorin.; Matrix biology : journal of the International Society for Matrix Biology; Vol 35. 2014 Apr. Dunkman AABuckley MRMienaltowski MJAdams SMThomas SJSatchell LKumar APathmanathan LBeason DPIozzo RVBirk DESoslowsky LJ The tendon injury response is influenced by decorin and biglycan.; Annals of biomedical engineering; Vol 42(3). 2014 Mar. Buckley MRSarver JJFreedman BRSoslowsky LJ The dynamics of collagen uncrimping and lateral contraction in tendon and the effect of ionic concentration.; Journal of biomechanics; Vol 46(13). 2013 Sep 3. Sevenler DBuckley MRKim Gvan der Meulen MCCohen IBonassar LJ Spatial periodicity in growth plate shear mechanical properties is disrupted by vitamin D deficiency.; Journal of biomechanics; Vol 46(10). 2013 Jun 21. Buckley MRDunkman AAReuther KEKumar APathmanathan LBeason DPBirk DESoslowsky LJ Validation of an empirical damage model for aging and in vivo injury of the murine patellar tendon.; Journal of biomechanical engineering; Vol 135(4). 2013 Apr. Buckley MRBonassar LJCohen I Localization of viscous behavior and shear energy dissipation in articular cartilage under dynamic shear loading.; Journal of biomechanical engineering; Vol 135(3). 2013 Mar 1. Dunkman AABuckley MRMienaltowski MJAdams SMThomas SJSatchell LKumar APathmanathan LBeason DPIozzo RVBirk DESoslowsky LJ Decorin expression is important for age-related changes in tendon structure and mechanical properties.; Matrix biology : journal of the International Society for Matrix Biology; Vol 32(1). 2013 Jan. Buckley MRHuffman GRIozzo RVBirk DESoslowsky LJ The location-specific role of proteoglycans in the flexor carpi ulnaris tendon.; Connective tissue research; Vol 54(6). 2013. Buckley MREvans EBMatuszewski PEChen YLSatchel LNElliott DMSoslowsky LJDodge GR Distributions of types I, II and III collagen by region in the human supraspinatus tendon.; Connective tissue research; Vol 54(6). 2013. Chandler EMSeo BRCalifano JPAndresen Eguiluz RCLee JSYoon CJTims DTWang JXCheng LMohanan SBuckley MRCohen INikitin AYWilliams RMGourdon DReinhart-King CAFischbach C Implanted adipose progenitor cells as physicochemical regulators of breast cancer.; Proceedings of the National Academy of Sciences of the United States of America; Vol 109(25). 2012 Jun 19. Chen TBuckley MCohen IBonassar LAwad HA Insights into interstitial flow, shear stress, and mass transport effects on ECM heterogeneity in bioreactor-cultivated engineered cartilage hydrogels.; Biomechanics and modeling in mechanobiology; Vol 11(5). 2012 May. Voleti PBBuckley MRSoslowsky LJ Tendon healing: repair and regeneration.; Annual review of biomedical engineering; Vol 14. 2012. Michalek AJBuckley MRBonassar LJCohen IIatridis JC The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus.; The spine journal : official journal of the North American Spine Society; Vol 10(12). 2010 Dec.