URMC / Labs / Altman Lab / Publications Recent Publications Scales TQSmith BBlanchard LMWixom NTuttle ETAltman BJPeppone LJMunger JCampbell TMCampbell EKHarris IS A whole food, plant-based diet reduces amino acid levels in patients with metastatic breast cancer.; medRxiv : the preprint server for health sciences. 2024 Oct 09. Knudsen-Clark AMAltman BJ Colorectal cancer clocks in on TIME.; Nature immunology. 2024 Jun 12. Knudsen-Clark AMMwangi DCazarin JHablitz LMKim MAltman BJ Circadian rhythms of macrophages are altered by the acidic pH of the tumor microenvironment.; bioRxiv : the preprint server for biology. 2024 Feb 16. Cazarin JAltman BJ Chewing the fat for good health: ACSM3 deficiency exacerbates metabolic syndrome.; The EMBO journal. 2024 Jan 23. Cazarin JDeRollo REShahidan SNABABurchett JBMwangi DKrishnaiah SHsieh ALWalton ZEBrooks RMello SSWeljie AMDang CVAltman BJ MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis.; PLoS genetics; Vol 19(8), pp. e1010904. 2023 Aug 28. DeRollo RECazarin JAhmad Shahidan SNABBurchett JBMwangi DKrishnaiah SHsieh ALWalton ZEBrooks RMello SSWeljie AMDang CVAltman BJ MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis.; bioRxiv : the preprint server for biology. 2023 Jan 04. Pariollaud MIbrahim LHIrizarry EMello RMChan ABAltman BJShaw RJBollong MJWiseman RLLamia KA Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer.; Science advances; Vol 8(39), pp. eabo1123. 2022 Sep 28. Kleckner ASAltman BJReschke JEKleckner IRCulakova EDunne RFMustian KMPeppone LJ Time-restricted Eating to Address Cancer-related Fatigue among Cancer Survivors: A Single-arm Pilot Study.; Journal of integrative oncology; Vol 11(4). 2022 May 30. Yee MMcDavid ANCohen EDHuyck HLPoole CAltman BJManiscalco WMDeutsch GHPryhuber GSO'Reilly MA Neonatal Hyperoxia Activates ATF4 to Stimulate Folate Metabolism and AT2 Cell Proliferation.; American journal of respiratory cell and molecular biology. 2022 Jan 19. Burchett JBKnudsen-Clark AMAltman BJ MYC Ran Up the Clock: The Complex Interplay between MYC and the Molecular Circadian Clock in Cancer.; International journal of molecular sciences; Vol 22(14). 2021 Jul 20. Bu YYoshida AChitnis NAltman BJTameire FOran AGennaro VArmeson KEMcMahon SBWertheim GBDang CVRuggero DKoumenis CFuchs SYDiehl JA A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival.; Nature cell biology; Vol 20(1). 2018 Jan. Krishnaiah SYWu GAltman BJGrowe JRhoades SDColdren FVenkataraman AOlarerin-George AOFrancey LJMukherjee SGirish SSelby CPCal SEr USianati BSengupta AAnafi RCKavakli IHSancar ABaur JADang CVHogenesch JBWeljie AM Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.; Cell metabolism; Vol 25(4). 2017 Apr 04. Altman BJHsieh ALGouw AMDang CV Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERBĪ±.; Nature communications; Vol 8. 2017 Mar 23. Altman BJStine ZEDang CV From Krebs to clinic: glutamine metabolism to cancer therapy.; Nature reviews. Cancer; Vol 16(10). 2016 Jan. Altman BJ Cancer Clocks Out for Lunch: Disruption of Circadian Rhythm and Metabolic Oscillation in Cancer.; Frontiers in cell and developmental biology; Vol 4. 2016. Altman BJHsieh ALSengupta AKrishnanaiah SYStine ZEWalton ZEGouw AMVenkataraman ALi BGoraksha-Hicks PDiskin SJBellovin DISimon MCRathmell JCLazar MAMaris JMFelsher DWHogenesch JBWeljie AMDang CV MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.; Cell metabolism; Vol 22(6). 2015 Dec 01. Stine ZEWalton ZEAltman BJHsieh ALDang CV MYC, Metabolism, and Cancer.; Cancer discovery; Vol 5(10). 2015 Oct. Hsieh ALWalton ZEAltman BJStine ZEDang CV MYC and metabolism on the path to cancer.; Seminars in cell & developmental biology; Vol 43. 2015 Jul. Xiang YStine ZEXia JLu YO'Connor RSAltman BJHsieh ALGouw AMThomas AGGao PSun LSong LYan BSlusher BSZhuo JOoi LLLee CGMancuso AMcCallion ASLe AMilone MCRayport SFelsher DWDang CV Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.; The Journal of clinical investigation; Vol 125(6). 2015 Jun. Altman BJRathmell JC Metabolic stress in autophagy and cell death pathways.; Cold Spring Harbor perspectives in biology; Vol 4(9). 2012 Sep 01. Altman BJDang CV Normal and cancer cell metabolism: lymphocytes and lymphoma.; The FEBS journal; Vol 279(15). 2012 Aug. Wang XEno COAltman BJZhu YZhao GOlberding KERathmell JCLi C ER stress modulates cellular metabolism.; The Biochemical journal; Vol 435(1). 2011 Apr 01. Coloff JLMason EFAltman BJGerriets VALiu TNichols ANZhao YWofford JAJacobs SRIlkayeva OGarrison SPZambetti GPRathmell JC Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.; The Journal of biological chemistry; Vol 286(7). 2011 Feb 18. Altman BJRathmell JC Autophagy: not good OR bad, but good AND bad.; Autophagy; Vol 5(4). 2009 May. Wieman HLHorn SRJacobs SRAltman BJKornbluth SRathmell JC An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking.; The Biochemical journal; Vol 418(2). 2009 Mar 01. Altman BJWofford JAZhao YColoff JLFerguson ECWieman HLDay AEIlkayeva ORathmell JC Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis.; Molecular biology of the cell; Vol 20(4). 2009 Feb. Zhao YAltman BJColoff JLHerman CEJacobs SRWieman HLWofford JADimascio LNIlkayeva OKelekar AReya TRathmell JC Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.; Molecular and cellular biology; Vol 27(12). 2007 Jun. Lue NFBosoy DMoriarty TJAutexier CAltman BLeng S Telomerase can act as a template- and RNA-independent terminal transferase.; Proceedings of the National Academy of Sciences of the United States of America; Vol 102(28). 2005 Jul 12. Macfarlan TKutney SAltman BMontross RYu JChakravarti D Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor.; The Journal of biological chemistry; Vol 280(8). 2005 Feb 25.