Education / Graduate Education / PhD Programs / Biochemistry & Molecular Biology / Faculty & Students / Students / Publications Recent Publications Kiliushik DGoenner CLaw MSchroeder GMSrivastava YJenkins JLWedekind JE Knotty is nice: metabolite binding and RNA-mediated gene regulation by the preQ1 riboswitch family.; The Journal of biological chemistry. 2024 Oct 30. Srivastava YAkinyemi ORohe TCPritchett EMBaker CDSharma AJenkins JLMathews DHWedekind JE Two riboswitch classes that share a common ligand-binding fold show major differences in the ability to accommodate mutations.; Nucleic acids research. 2024 Oct 16. Das DKhor ESJiang FHe JKawakami YWainwright LHollinger JGeiger JLiu HMeng FPorter GAJin ZMurphy PYao P Loss-of-function of RNA-binding protein PRRC2B causes translational defects and congenital cardiovascular malformation.; medRxiv : the preprint server for health sciences. 2024 Sep 27. Lin MHJensen MKElrod NDChu HFHaseley MBeam ACHuang KLChiang WRussell WKWilliams KPröschel CWagner EJTong L Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function.; Molecular cell. 2024 Jul 08. Pan YAdachi HHe XChen JLYu YTBoutz PL Updated Pseudo-seq Protocol for Transcriptome-Wide Detection of Pseudouridines.; Bio-protocol; Vol 14(9), pp. e4985. 2024 May 05. Haugen RJBarnier CElrod NDLuo HJensen MKJi PSmibert CALipshitz HDWagner EJFreddolino PLGoldstrohm AC Regulation of the Drosophila transcriptome by Pumilio and the CCR4-NOT deadenylase complex.; RNA (New York, N.Y.). 2024 Apr 16. Tabata Fukushima CDancil ISClary HShah NNadtochiy SMBrookes PS Reactive oxygen species generation by reverse electron transfer at mitochondrial complex I under simulated early reperfusion conditions.; Redox biology; Vol 70, pp. 103047. 2024 Jan 27. Zhao YZheng ZZhang ZXu YHillpot ELin YSZakusilo FTLu JYAblaeva JBiashad SAMiller RANevo ESeluanov AGorbunova V Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle.; Nature communications; Vol 14(1), pp. 8054. 2023 Dec 05. Schroeder GMKiliushik DJenkins JLWedekind JE Structure and function analysis of a type III preQ1-I riboswitch from E. coli reveals direct metabolite-sensing by the Shine-Dalgarno sequence.; The Journal of biological chemistry. 2023 Sep 01. Haugen RJBarnier CElrod NDLuo HJensen MKJi PSmibert CALipshitz HDWagner EJFreddolino PLGoldstrohm AC Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase.; bioRxiv : the preprint server for biology. 2023 Aug 30. Haghani ALi CZRobeck TRZhang JLu ATAblaeva JAcosta-Rodríguez VAAdams DMAlagaili ANAlmunia JAloysius AAmor NMSArdehali RArneson ABaker CSBanks GBelov KBennett NCBlack PBlumstein DTBors EKBreeze CEBrooke RTBrown JLCarter GCaulton ACavin JMChakrabarti LChatzistamou IChavez ASChen HCheng KChiavellini PChoi OWClarke SCook JACooper LNCossette MLDay JDeYoung JDirocco SDold CDunnum JLEhmke EEEmmons CKEmmrich SErbay EErlacher-Reid CFaulkes CGFei ZFerguson SHFinno CJFlower JEGaillard JMGarde EGerber LGladyshev VNGoya RGGrant MJGreen CBHanson MBHart DWHaulena MHerrick KHogan ANHogg CJHore TAHuang TIzpisua Belmonte JCJasinska AJJones GJourdain EKashpur OKatcher HKatsumata EKaza VKiaris HKobor MSKordowitzki PKoski WRKrützen MKwon SBLarison BLee SGLehmann MLemaître JFLevine AJLi XLi CLim ARLin DTSLindemann DMLiphardt SWLittle TJMacoretta NMaddox DMatkin COMattison JAMcClure MMergl JMeudt JJMontano GAMozhui KMunshi-South JMurphy WJNaderi ANagy MNarayan PNathanielsz PWNguyen NBNiehrs CNyamsuren BO'Brien JKGinn POOdom DTOphir AGOsborn SOstrander EAParsons KMPaul KCPedersen ABPellegrini MPeters KJPetersen JLPietersen DWPinho GMPlassais JPoganik JRPrado NAReddy PRey BRitz BRRobbins JRodriguez MRussell JRydkina ESailer LLSalmon ABSanghavi ASchachtschneider KMSchmitt DSchmitt TSchomacher LSchook LBSears KESeifert AWShafer ABAShindyapina AVSimmons MSingh KSinha ISlone JSnell RGSoltanmohammadi ESpangler MLSpriggs MStaggs LStedman NSteinman KJStewart DTSugrue VJSzladovits BTakahashi JSTakasugi MTeeling ECThompson MJVan Bonn BVernes SCVillar DVinters HVVu HWallingford MCWang NWilkinson GSWilliams RWYan QYao MYoung BGZhang BZhang ZZhao YZhao PZhou WZoller JAErnst JSeluanov AGorbunova VYang XWRaj KHorvath S DNA methylation networks underlying mammalian traits.; Science (New York, N.Y.); Vol 381(6658), pp. eabq5693. 2023 Aug 11. Liu XBurke RMLighthouse JKBaker CDDirkx RAKang BChakraborty YMickelsen DMTwardowski JMello SSAshton JMSmall EM P53 Regulates the Extent of Fibroblast Proliferation and Fibrosis in Left Ventricle Pressure Overload.; Circulation research. 2023 Jul 06. Lazaro-Pena MICornwell ABDiaz-Balzac CADas RWard ZCMacoretta NThakar JSamuelson AV Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans aging and systemically regulates longevity from serotonergic and GABAergic neurons.; eLife; Vol 12. 2023 Jun 20. Lindström SWang LFeng HMajumdar AHuo SMacdonald JHarrison TTurman CChen HMancuso NBammler TGallinger SGruber SBGunter MJLe Marchand LMoreno VOffit KDe Vivo IO'Mara TASpurdle ABTomlinson IFitzgerald RGharahkhani PGockel IJankowski JMacgregor SSchumacher JBarnholtz-Sloan JBondy MLHoulston RSJenkins RBMelin BWrensch MBrennan PChristiani DCJohansson MMckay JAldrich MCAmos CILandi MTTardon ABishop DTDemenais FGoldstein AMIles MMKanetsky PALaw MHAmundadottir LTStolzenberg-Solomon RWolpin BMKlein APetersen GRisch HChanock SJPurdue MPScelo GPharoah PKar SHung RJPasaniuc BKraft P Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions.; Journal of the National Cancer Institute; Vol 115(6), pp. 712-732. 2023 Jun 08. Rizig MBandres-Ciga SMakarious MBOjo OCrea PWAbiodun OLevine KSAbubakar SAchoru CVitale DAdeniji OAgabi OKoretsky MJAgulanna UHall DAAkinyemi RXie TAli MShamim EAAni-Osheku IPadmanaban MArigbodi OStandaert DGBello ADean MErameh CElsayed IFarombi TOkunoye OFawale MBillingsley KJImarhiagbe FJerez PAIwuozo EBaker BKomolafe MMalik LNwani PDaida KNwazor EMiano-Burkhardt ANyandaiti YFang ZHObiabo YKluss JHOdeniyi OHernandez DOdiase FTayebi NOjini FSidranksy EOnwuegbuzie GD'Souza AMOsaigbovo GBerhe BOsemwegie NReed XOshinaike OLeonard HOtubogun FAlvarado CXOyakhire SOzomma SSamuel STaiwo FWahab KZubair YIwaki HKim JJMorris HRHardy JNalls MHeilbron KNorcliffe-Kaufmann LBlauwendraat CHoulden HSingleton AOkubadejo N Genome-wide Association Identifies Novel Etiological Insights Associated with Parkinson's Disease in African and African Admixed Populations.; medRxiv : the preprint server for health sciences. 2023 May 07. VanderWal ARPark JUPolevoda BNicosia JKMolina Vargas AMKellogg EHO'Connell MR Csx28 is a membrane pore that enhances CRISPR-Cas13b-dependent antiphage defense.; Science (New York, N.Y.); Vol 380(6643), pp. 410-415. 2023 Apr 27. Haycock PCBorges MCBurrows KLemaitre RNBurgess SKhankari NKTsilidis KKGaunt TRHemani GZheng JTruong TBirmann BMOMara TSpurdle ABIles MMLaw MHSlager SLSaberi Hosnijeh FMariosa DCotterchio MCerhan JRPeters UEnroth SGharahkhani PLe Marchand LWilliams ACBlock RCAmos CIHung RJZheng WGunter MJSmith GDRelton CMartin RM The association between genetically elevated polyunsaturated fatty acids and risk of cancer.; EBioMedicine; Vol 91, pp. 104510. 2023 Apr 20. Haycock PCBorges MCBurrows KLemaitre RNHarrison SBurgess SChang XWestra JKhankari NKTsilidis KKGaunt THemani GZheng JTruong TO'Mara TASpurdle ABLaw MHSlager SLBirmann BMSaberi Hosnijeh FMariosa DAmos CIHung RJZheng WGunter MJDavey Smith GRelton CMartin RM Design and quality control of large-scale two-sample Mendelian randomization studies.; International journal of epidemiology; Vol 52(5), pp. 1498-1521. 2023 Apr 12. Adachi HPan YHe XChen JLKlein BPlatenburg GMorais PBoutz PYu YT Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes.; Molecular cell. 2023 Feb 03. Fukushima CTDancil ISClary HShah NNadtochiy SMBrookes PS Reactive Oxygen Species Generation by Reverse Electron Transfer at Mitochondrial Complex I Under Simulated Early Reperfusion Conditions.; bioRxiv : the preprint server for biology. 2023 Jan 21. Batchelor WBAnwaruddin SWang DDPerpetua EMKrishnaswami AVelagapudi PWyman JFFullerton DKeegan PPhillips ARoss LMaini BBernacki GPanjrath GSLee JGeske JBWelt FThakker PDDeswal APark KMack MJLeon MLewis SHolmes D The Multidisciplinary Heart Team in Cardiovascular Medicine: Current Role and Future Challenges.; JACC. Advances; Vol 2(1), pp. 100160. 2023 Jan 11. Galindo RJUppal TSMcCoy RGUmpierrez GEAli MK Use and continuity of weight-modifying medications among adults with diabetes and overweight/obesity: US population study.; Obesity (Silver Spring, Md.). 2023 Jan 02. Lin MHJensen MKElrod NDHuang KLWelle KAWagner EJTong L Inositol hexakisphosphate is required for Integrator function.; Nature communications; Vol 13(1), pp. 5742. 2022 Sep 30. Anjum HYasmin FAli SHSunesara SKhawaja AMHaji Datoo AAli MSurani S Think Outside the Box: A Rare Presentation of Schistosomiasis in the United States.; Cureus; Vol 14(8), pp. e27970. 2022 Aug 13. Barker MSathananthan JPerdoncin EDevireddy CKeegan PGrubb KPop AMDepta JPRai DAbtahian FSpence MSMailey JMuir DFRusso MJPineda-Salazar JOkoh ASmith MDahle TGRana MAlfadhel MMeier DChatfield AAkodad MChuang ASamuel RNestelberger TMcAlister CLauck SWebb JGWood DA Same-Day Discharge Post-Transcatheter Aortic Valve Replacement During the COVID-19 Pandemic: The Multicenter PROTECT TAVR Study.; JACC. Cardiovascular interventions; Vol 15(6), pp. 590-598. 2022 Mar 28. Chandrasekar EKAli MKWei JNarayan KVOwens-Gary MDBullard KM Trends in depression by glycemic status: Serial cross-sectional analyses of the National Health and Nutrition Examination Surveys, 2005-2016.; Primary care diabetes. 2022 Mar 07. Horvath SHaghani AMacoretta NAblaeva JZoller JALi CZZhang JTakasugi MZhao YRydkina EZhang ZEmmrich SRaj KSeluanov AFaulkes CGGorbunova V DNA methylation clocks tick in naked mole rats but queens age more slowly than nonbreeders.; Nature aging; Vol 2(1). 2022 Jan. Lei XMudiyanselage TBZhang YBian CLan WYu NPan Y A comprehensive survey on computational methods of non-coding RNA and disease association prediction.; Briefings in bioinformatics; Vol 22(4). 2021 Jul 20. Chen HMajumdar AWang LKar SBrown KMFeng HTurman CDennis JEaston DMichailidou KSimard JBishop TCheng ICHuyghe JRSchmit SLO'Mara TASpurdle ABGharahkhani PSchumacher JJankowski JGockel IBondy MLHoulston RSJenkins RBMelin BLesseur CNess ARDiergaarde BOlshan AFAmos CIChristiani DCLandi MTMcKay JDBrossard MIles MMLaw MHMacGregor SBeesley JJones MRTyrer JWinham SJKlein APPetersen GLi DWolpin BMEeles RAHaiman CAKote-Jarai ZSchumacher FRBrennan PChanock SJGaborieau VPurdue MPPharoah PHung RJAmundadottir LTKraft PPasaniuc BLindström S Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals.; HGG advances; Vol 2(3), pp. 100041. 2021 Jun 12. Zhang YDHurson ANZhang HChoudhury PPEaston DFMilne RLSimard JHall PMichailidou KDennis JSchmidt MKChang-Claude JGharahkhani PWhiteman DCampbell PTHoffmeister MJenkins MPeters UHsu LGruber SBCasey GSchmit SLO'Mara TASpurdle ABThompson DJTomlinson IDe Vivo ILandi MTLaw MHIles MMDemenais FKumar RMacGregor SBishop DTWard SVBondy MLHoulston RWiencke JKMelin BBarnholtz-Sloan JKinnersley BWrensch MRAmos CIHung RJBrennan PMcKay JCaporaso NEBerndt SIBirmann BMCamp NJKraft PRothman NSlager SLBerchuck APharoah PDPSellers TAGayther SAPearce CLGoode ELSchildkraut JMMoysich KBAmundadottir LTJacobs EJKlein APPetersen GMRisch HAStolzenberg-Solomon RZWolpin BMLi DEeles RAHaiman CAKote-Jarai ZSchumacher FRAl Olama AAPurdue MPScelo GDalgaard MDGreene MHGrotmol TKanetsky PAMcGlynn KANathanson KLTurnbull CWiklund FChanock SJChatterjee NGarcia-Closas M Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.; Nature communications; Vol 11(1), pp. 3353. 2020 Jul 03. Hulver MJTrautman JPGoodwin APRoszczenko SKFogarty KHMiller HB Human Tat-specific factor 1 binds the HIV-1 genome and selectively transports HIV-1 RNAs.; Molecular biology reports; Vol 47(3). 2020 Mar. Tombline GGigas JMacoretta NZacher MEmmrich SZhao YSeluanov AGorbunova V Proteomics of Long-Lived Mammals.; Proteomics. 2019 Nov 18. Tan LKe ZTombline GMacoretta NHayes KTian XLv RAblaeva JGilbert MBhanu NVYuan ZFGarcia BAShi YGShi YSeluanov AGorbunova V Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming.; Stem cell reports; Vol 9(5). 2017 Nov 14. Haycock PCBurgess SNounu AZheng JOkoli GNBowden JWade KHTimpson NJEvans DMWilleit PAviv AGaunt TRHemani GMangino MEllis HPKurian KMPooley KAEeles RALee JEFang SChen WVLaw MHBowdler LMIles MMYang QWorrall BBMarkus HSHung RJAmos CISpurdle ABThompson DJO'Mara TAWolpin BAmundadottir LStolzenberg-Solomon RTrichopoulou AOnland-Moret NCLund EDuell EJCanzian FSeveri GOvervad KGunter MJTumino RSvenson Uvan Rij ABaas AFBown MJSamani NJvan t'Hof FNGTromp GJones GTKuivaniemi HElmore JRJohansson MMckay JScelo GCarreras-Torres RGaborieau VBrennan PBracci PMNeale REOlson SHGallinger SLi DPetersen GMRisch HAKlein APHan JAbnet CCFreedman NDTaylor PRMaris JMAben KKKiemeney LAVermeulen SHWiencke JKWalsh KMWrensch MRice TTurnbull CLitchfield KPaternoster LStandl MAbecasis GRSanGiovanni JPLi YMijatovic VSapkota YLow SKZondervan KTMontgomery GWNyholt DRvan Heel DAHunt KArking DEAshar FNSotoodehnia NWoo DRosand JComeau MEBrown WMSilverman EKHokanson JECho MHHui JFerreira MAThompson PJMorrison ACFelix JFSmith NLChristiano AMPetukhova LBetz RCFan XZhang XZhu CLangefeld CDThompson SDWang FLin XSchwartz DAFingerlin TRotter JICotch MFJensen RAMunz MDommisch HSchaefer ASHan FOllila HMHillary RPAlbagha ORalston SHZeng CZheng WShu XOReis AUebe SHüffmeier UKawamura YOtowa TSasaki THibberd MLDavila SXie GSiminovitch KBei JXZeng YXFörsti AChen BLandi SFranke AFischer AEllinghaus DFlores CNoth IMa SFFoo JNLiu JKim JWCox DGDelattre OMirabeau OSkibola CFTang CSGarcia-Barcelo MChang KPSu WHChang YSMartin NGGordon SWade TDLee CKubo MCha PCNakamura YLevy DKimura MHwang SJHunt SSpector TSoranzo NManichaikul AWBarr RGKahali BSpeliotes EYerges-Armstrong LMCheng CYJonas JBWong TYFogh ILin KPowell JFRice KRelton CLMartin RMDavey Smith G Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.; JAMA oncology; Vol 3(5), pp. 636-651. 2017 May 01.