Recent Publications

• 1. Tumenbayar BI
  2. Tutino VM
  3. Brazzo JA
  4. Yao P
  5. Bae Y
  FAK and p130Cas modulate stiffness-mediated early transcription and cellular metabolism.; bioRxiv : the preprint server for biology. 2024 Jan 16.
• 1. Wu J
  2. Hollinger J
  3. Bonanno E
  4. Jiang F
  5. Yao P
  Cardiomyocyte-Specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy.; Cells; Vol 13(1). 2023 Dec 22.
• 1. Wu J
  2. Hollinger J
  3. Bonanno E
  4. Jiang F
  5. Yao P
  Cardiomyocyte-specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy.; bioRxiv : the preprint server for biology. 2023 Sep 22.
• 1. Wu J
  2. Subbaiah KCV
  3. Hedaya O
  4. Chen S
  5. Munger J
  6. Tang WHW
  7. Yan C
  8. Yao P
  FAM210A regulates mitochondrial translation and maintains cardiac mitochondrial homeostasis.; Cardiovascular research. 2023 Jul 31.
• 1. Hollinger J
  2. Wu J
  3. Awayda KM
  4. O'Connell MR
  5. Yao P
  Expression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli.; Protein expression and purification; Vol 210, pp. 106322. 2023 Jun 15.
• 1. Hedaya OM
  2. Subbaiah KCV
  3. Jiang F
  4. Xie LH
  5. Wu J
  6. Khor E
  7. Zhu M
  8. Mathews DH
  9. Proschel C
  10. Yao P
  Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy.; bioRxiv : the preprint server for biology. 2023 Jun 15.
• 1. Wu J
  2. Subbaiah KCV
  3. Hedaya O
  4. Chen S
  5. Munger J
  6. Tang WHW
  7. Yan C
  8. Yao P
  FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.; bioRxiv : the preprint server for biology. 2023 May 22.
• 1. Jiang F
  2. Hedaya OM
  3. Khor E
  4. Wu J
  5. Auguste M
  6. Yao P
  RNA binding protein PRRC2B mediates translation of specific mRNAs and regulates cell cycle progression.; Nucleic acids research. 2023 May 01.
• 1. Subbaiah KCV
  2. Wu J
  3. Tang WHW
  4. Yao P
  Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis.; Journal of cardiovascular development and disease; Vol 10(2). 2023 Jan 29.
• 1. Subbaiah KCV
  2. Wu J
  3. Tang WHW
  4. Yao P
  FAM114A1 influences cardiac pathological remodeling by regulating angiotensin II signaling.; JCI insight. 2022 Jun 07.
• 1. Wu J
  2. Venkata Subbaiah KC
  3. Jiang F
  4. Hedaya O
  5. Mohan A
  6. Yang T
  7. Welle K
  8. Ghaemmaghami S
  9. Tang WHW
  10. Small E
  11. Yan C
  12. Yao P
  MicroRNA-574 regulates FAM210A expression and influences pathological cardiac remodeling.; EMBO molecular medicine. 2020 Dec 28.
• 1. Lyu QR
  2. Yao P
  3. Miano JM
  Generating a CRISPR knockout mouse through a strong premature termination codon: a cautionary tale.; Journal of biomedical research; Vol 35(2). 2020 Dec 25.
• 1. Wu J
  2. Subbaiah KCV
  3. Xie LH
  4. Jiang F
  5. Khor ES
  6. Mickelsen DM
  7. Myers JR
  8. Tang WW
  9. Yao P
  Glutamyl-Prolyl-tRNA Synthetase Regulates Proline-Rich Pro-fibrotic Protein Synthesis During Cardiac Fibrosis.; Circulation research. 2020 Jul 01.
• 1. Zhao S
  2. Dejanovic D
  3. Yao P
  4. Bhilocha S
  5. Sadler T
  6. Schirbel A
  7. West G
  8. Doyon G
  9. Lopez R
  10. Mao R
  11. Kurada S
  12. El Ouali S
  13. Grassl G
  14. Fox PL
  15. Cruise M
  16. Worthley DL
  17. de la Motte C
  18. Fiocchi C
  19. Rieder F
  Selective deletion of MyD88 signaling in α-SMA positive cells ameliorates experimental intestinal fibrosis via post-transcriptional regulation.; Mucosal immunology; Vol 13(4). 2020 Jul.
• 1. Yao P
  2. Fox PL
  Aminoacyl-tRNA synthetases in cell signaling.; The Enzymes; Vol 48. 2020.
• 1. Ji C
  2. Li Y
  3. Kittredge A
  4. Hopiavuori A
  5. Ward N
  6. Yao P
  7. Fukuda Y
  8. Zhang Y
  9. Tsang SH
  10. Yang T
  Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations.; Scientific reports; Vol 9(1). 2019 Dec 13.
• 1. Chen S
  2. Zhang Y
  3. Lighthouse JK
  4. Mickelsen DM
  5. Wu J
  6. Yao P
  7. Small EM
  8. Yan C
  A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction.; Circulation. 2019 Dec 05.
• 1. Venkata Subbaiah KC
  2. Wu J
  3. Potdar A
  4. Yao P
  hnRNP L-mediated RNA switches function as a hypoxia-induced translational regulon.; Biochemical and biophysical research communications; Vol 516(3). 2019 Aug 27.
• 1. Venkata Subbaiah KC
  2. Hedaya O
  3. Wu J
  4. Jiang F
  5. Yao P
  Mammalian RNA switches: Molecular rheostats in gene regulation, disease, and medicine.; Computational and structural biotechnology journal; Vol 17. 2019.
• 1. Halawani D
  2. Gogonea V
  3. DiDonato JA
  4. Pipich V
  5. Yao P
  6. China A
  7. Topbas C
  8. Vasu K
  9. Arif A
  10. Hazen SL
  11. Fox PL
  Structural control of caspase-generated glutamyl-tRNA synthetase by appended noncatalytic WHEP domains.; The Journal of biological chemistry; Vol 293(23). 2018 Jun 08.
• 1. Arif A
  2. Yao P
  3. Terenzi F
  4. Jia J
  5. Ray PS
  6. Fox PL
  The GAIT translational control system.; Wiley interdisciplinary reviews. RNA; Vol 9(2). 2018 Mar.
• 1. Techasintana P
  2. Ellis JS
  3. Glascock J
  4. Gubin MM
  5. Ridenhour SE
  6. Magee JD
  7. Hart ML
  8. Yao P
  9. Zhou H
  10. Whitney MS
  11. Franklin CL
  12. Martindale JL
  13. Gorospe M
  14. Davis WJ
  15. Fox PL
  16. Li X
  17. Atasoy U
  The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4+ Th2 Differentiation.; ImmunoHorizons; Vol 1(6). 2017 Aug 01.
• 1. Yao P
  2. Wu J
  3. Lindner D
  4. Fox PL
  Interplay between miR-574-3p and hnRNP L regulates VEGFA mRNA translation and tumorigenesis.; Nucleic acids research. 2017 May 17.
• 1. Yao P
  2. Eswarappa SM
  3. Fox PL
  "Translational control mechanisms in angiogenesis and vascular biology."; Current Atherosclerosis Reports. 2015 Jan 01.
• 1. Huang Q
  2. Zhou X
  3. Hu Q
  4. Lei H
  5. Fang Z
  6. Yao P
  7. Wang AE
  "A bridge between the aminoacylation and editing domains of leucyl-tRNA synthetase is crucial for its synthetic activity."; RNA; Vol 20, pp. 1440-1450. 2014 Jan 01.
• 1. Jia J
  2. Yao P
  3. Arif A
  4. Fox PL
  Regulation and dysregulation of 3'UTR-mediated translational control.; Current opinion in genetics & development; Vol 23(1). 2013 Feb.
• 1. Yao P
  2. Potdar AA
  3. Ray PS
  4. Eswarappa SM
  5. Flagg AC
  6. Willard B
  7. Fox PL
  The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA.; PLoS biology; Vol 11(8). 2013.
• 1. Zhou H
  2. Yu M
  3. Fukuda K
  4. Im J
  5. Yao P
  6. Cui W
  7. Bulek K
  8. Zepp J
  9. Wan Y
  10. Kim TW
  11. Yin W
  12. Ma V
  13. Thomas J
  14. Gu J
  15. Wang J
  16. DiCorleto PE
  17. Fox PL
  18. Qin J
  19. Li AX
  "IRAK-M mediates Toll-like receptor/IL-1R-induced NFkB activation and cytokine production."; EMBO Journal; Vol 32, pp. 583-596. 2013 Jan 01.
• 1. Herjan T
  2. Yao P
  3. Qian W
  4. Li X
  5. Liu C
  6. Bulek K
  7. Sun D
  8. Yang W
  9. Zhu J
  10. He A
  11. Carman JA
  12. Erzurum SC
  13. Lipshitz HD
  14. Fox PL
  15. Hamilton TA
  16. Li AX
  "HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization."; Journal of Immunology; Vol 191, pp. 640-649. 2013 Jan 01.
• 1. Yao P
  2. Fox PL
  "Aminoacyl-tRNA synthetases in medicine and disease."; EMBO Molecular Medicine; Vol 5, pp. 332-343. 2013 Jan 01.
• 1. Yao P
  2. Poruri K
  3. Martinis SA
  4. Fox PL
  "Non-catalytic regulation of gene expression by aminoacyl-tRNA synthetases."; Topics in Current Chemistry; Vol 344, pp. 167-187. 2013 Jan 01.
• 1. Yao P
  2. Potdar AA
  3. Arif A
  4. Ray PS
  5. Mukhopadhyay R
  6. Willard B
  7. Xu Y
  8. Yan J
  9. Saidel GM
  10. Fox PL
  Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression.; Cell; Vol 149(1). 2012 Mar 30.
• 1. Yao P
  2. Fox PL
  "A truncated tRNA synthetase directs a 'translational trickle' of gene expression."; Cell Cycle; Vol 11. 2012 Jan 01.
• 1. Huang Q
  2. Yao P
  3. Eriani G
  4. Wang E
  "In vivo identification of essential nucleotides in tRNALeu to its functions by using a constructed yeast tRNALeu knockout strain."; Nucleic Acids Research; Vol 40, pp. 10463-10477. 2012 Jan 01.
• 1. Jafarifar F
  2. Yao P
  3. Eswarappa SM
  4. Fox PL
  "Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L."; EMBO Journal; Vol 30:, pp. 1324-1334. 2011 Jan 01.
• 1. Chen X
  2. Ma J
  3. Tan M
  4. Yao P
  5. Hu Q
  6. Eriani G
  7. Wang E
  "Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase."; Nucleic Acids Research; Vol 39:, pp. 235-247. 2011 Jan 01.
• 1. Yao P
  2. Fox PL
  "Sex lethal and upstream ORFs: a bait-and-trap system for ribosomes."; Genome Biology; Vol 12:(12). 2011 Jan 01.
• 1. Yin W
  2. Wan Y
  3. Kim TW
  4. Yao P
  5. Xiao H
  6. Zhou H
  7. Xiao J
  8. Fox P
  9. Li X
  "The kinase activity of interleukin-1 receptor-associated kinase 2 is essential for lipopolysaccharide-mediated cytokine and chemokine mRNA stability and translation."; J Interferon Cytokine Research; Vol 31:, pp. 415-422. 2011 Jan 01.
• 1. Zhu B
  2. Yao P
  3. Tan M
  4. Eriani G
  5. Wang ED
  tRNA-independent pretransfer editing by class I leucyl-tRNA synthetase.; The Journal of biological chemistry; Vol 284(6). 2009 Feb 06.
• 1. Zhou X
  2. Yao P
  3. Zhu B
  4. Ruan L
  5. Wang E
  "A unique insertion in the CP1 domain of Giardia lamblia leucyl-tRNA synthetase."; Biochemistry; Vol 48:, pp. 1340-1347. 2009 Jan 01.
• 1. He R
  2. Zu L
  3. Yao P
  4. Chen X
  5. Wang E
  "Two non-redundant fragments in the N-terminal peptide of human cytosolic methionyl-tRNA synthetase were indispensable for the multi-synthetase complex incorporation and enzyme activity."; Biochimica et Biophysica Acta; Vol 1794:, pp. 347-354. 2009 Jan 01.
• 1. Ray PS
  2. Jia J
  3. Yao P
  4. Majumder M
  5. Hatzoglou M
  6. Fox PL
  "A stress-responsive RNA switch regulates VEGFA expression."; Nature; Vol 457:, pp. 915-919. 2008 Jan 01.
• 1. Yao P
  2. Zhou X
  3. He R
  4. Xue M
  5. Zheng Y
  6. Wang Y
  7. Wang E
  "Unique residues crucial for optimal editing in the yeast cytoplasmic leucyl-tRNA synthetase revealed by a novel knockout yeast strain."; Journal of Biological Chemistry; Vol 283:, pp. 22591-22600. 2008 Jan 01.
• 1. Yao P
  2. Zhu B
  3. Jaeger S
  4. Eriani G
  5. Wang E
  "Recognition of tRNALeu by Aquifex aeolicus leucyl-tRNA synthetase during aminoacylation and editing steps."; Nucleic Acids Research; Vol 36:, pp. 2728-2738. 2008 Jan 01.